We fabricated a simple, cheap, and functional surface enhanced Raman scattering substrate for biomedical application. Hot spots between two close silver nanoparticles distributed in the skeleton of a three-dimensional porous membrane, especially in the pores, were formed. The dual poles of micropores in the membrane were discussed. The pores could protect the silver nanoparticles in the pores from being oxidized, which makes the membrane effective for a longer period of time. In addition,Staphylococcus aureuscells could be trapped by the micropores and then the Raman signal became stronger, indicating that the functional surface enhanced Raman scattering substrate is reliable.
AbstractWe study the role of a strong electron confinement on the surface-enhanced Raman scattering from molecules adsorbed on small noble-metal nanoparticles. We describe a novel enhancement mechanism which originates from the different effect that confining potential has on s-band and d-band electrons. We demonstrate that the interplay between finite-size and screening efects in the nanoparticle surface layer leads to an enhancement of the surface plasmon local field acting on a molecule located in a close proximity to the metal surface. Our calculations show that the additional enhancement of the Raman signal is especially strong for small nanometer-sized nanoparticles.
Herein, a universal surface-enhanced Raman scattering (SERS) detection platform based on enzyme-guided crystal growth has been fabricated for the first time.
A facile and convenient strategy to detect polycyclic aromatic hydrocarbons is presented, using graphene–Ag nanoparticle hybrids as a surface-enhanced Raman scattering substrate.
A Biomedical Surface Enhanced Raman Scattering Substrate: Functionalized Three-Dimensional Porous Membrane Decorated with Silver Nanoparticles
