scholarly journals Phenolic profile and biological activity of Hypericum perforatum L.: Can roots be considered as a new source of natural compounds?

2018 ◽  
Vol 117 ◽  
pp. 301-310 ◽  
Author(s):  
O. Tusevski ◽  
M. Krstikj ◽  
J.P. Stanoeva ◽  
M. Stefova ◽  
S. Gadzovska Simic
Keyword(s):  
Biological Activity ◽  
Hypericum Perforatum ◽  
Natural Compounds ◽  
Phenolic Profile ◽  
Hypericum Perforatum L

scholarly journals BIOLOGICAL ACTIVITY OF HYPERICUM PERFORATUM L. (HYPERICACEAE): A REVIEW

2021 ◽  
Vol 9 (1) ◽  
pp. 17-31
Author(s):  
A. L. Budantsev ◽  
V. A. Prikhodko ◽  
I. V. Varganova ◽  
S. V. Okovityi
Keyword(s):  
Biological Activity ◽  
Hypericum Perforatum ◽  
Hypericum Perforatum L

Comparative chemical composition and variability of biological activity of methanolic extracts from Hypericum perforatum L.

2005 ◽  
Vol 19 (3) ◽  
pp. 295-303 ◽  
Author(s):  
F. Conforti ◽  
G.A. Statti ◽  
R. Tundis ◽  
A. Bianchi ◽  
C. Agrimonti ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chemical Composition ◽  
Hypericum Perforatum ◽  
Methanolic Extracts ◽  
Hypericum Perforatum L

scholarly journals Environmental Factors do not Affect the Phenolic Profile of Hypericum perforatum Growing Wild in Bosnia and Herzegovina

2017 ◽  
Vol 12 (9) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Sanja Ćavar Zeljković ◽  
Erna Karalija ◽  
Adisa Parić ◽  
Edina Muratović ◽  
Petr Tarkowski
Keyword(s):  
Environmental Factors ◽  
Bosnia And Herzegovina ◽  
Hypericum Perforatum ◽  
Analytical Tool ◽  
Phenolic Profile ◽  
Glycosidic Bonds ◽  
Fractionation Procedure ◽  
Powerful Analytical Tool ◽  
Hypericum Perforatum L ◽  
First Time

Using appropriate isolation and fractionation procedure, and UHPLC-MS/MS as powerful analytical tool, comprehensive phenolic acid profile of leaves and flowers of Hypericum perforatum L., growing wild in Bosnia and Herzegovina, has been analyzed for the first time. The phenolic acids were isolated from plant tissue, liberated from esters and glycosidic bonds, and then analyzed as free acids. Results show that free forms of caffeic and chlorogenic acid were the most abundant. Generally, the content of acids is higher in flowers than in leaves, but environmental factors do not significantly influence chemical composition of this medicinal plant.

Determination of Hypericin in St. John's Wort (Hypericum perforatum L.) extracts using HPLC-ED

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
E Sofic ◽  
A Copra Janicijevic ◽  
M Maksimovic ◽  
I Tahirovic ◽  
L Klepo ◽  
...  
Keyword(s):  
Hypericum Perforatum ◽  
St John’S Wort ◽  
St John's Wort ◽  
Hypericum Perforatum L

Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland

2017 ◽  
Vol 68 (9) ◽  
pp. 2014-2017
Author(s):  
Jelena Savici ◽  
Oana Maria Boldura ◽  
Cornel Balta ◽  
Diana Brezovan ◽  
Florin Muselin ◽  
...  
Keyword(s):  
Drinking Water ◽  
Adrenal Gland ◽  
Hexavalent Chromium ◽  
Structural Damage ◽  
Hypericum Perforatum ◽  
Adrenal Glands ◽  
Expression Level ◽  
Apoptotic Pathway ◽  
Hypericum Perforatum L ◽  
Induction Of Apoptosis

This study was carried out to test the possibility of hexavalent chromium administration through drinking water to induce the structural damage in rat�s adrenal glands and the possibility of Hypericum perforatum extract to faith against chromium aggression. Chromium induced cellular stress was determined by the expression level assessment of the Bcl2 genes family, known to modulate the apoptotic pathway. Obtained results showed that exposure to chromium altered adrenal glands morphology, by induction of apoptosis. When Hypericum perforatum extract was administered expression level of Bcl2 genes and histological lesions in adrenal glands were significantly reduced.

Evaluating the Content of Active Principles from Wild Hypericum perforatum L. in Various Harvesting Seasons

2018 ◽  
Vol 69 (7) ◽  
pp. 1892-1897
Author(s):  
Elena Ionescu ◽  
Tanta Verona Iordache ◽  
Carmen Elena Tebrencu ◽  
Ruxandra Mihaela Cretu ◽  
Ana Mihaela Florea ◽  
...  
Keyword(s):  
Plant Material ◽  
Hypericum Perforatum ◽  
Hypericum Perforatum L

Hypericum perforatum L., traditionally called St. John�s Wort has been used for decades as a phyto-therapeutic herb due to antidepressant, antimicrobial and antiseptic properties. As a result, the presented study evaluates the influence of the harvesting season for the Hypericum perforatum L. plant material, which is crucial for obtaining significant amounts of active principles.

Development of Single-step Protocols for the Separation of Naphtodianthrones from St. John�s Wort Extracts

2018 ◽  
Vol 69 (8) ◽  
pp. 2295-2299
Author(s):  
Elena Ionescu ◽  
Tanta Verona Iordache ◽  
Carmen Elena Tebrencu ◽  
Ruxandra Mihaela Cretu ◽  
Ana Mihaela Florea ◽  
...  
Keyword(s):  
Hypericum Perforatum ◽  
Single Step ◽  
Anti Cancer ◽  
Hypericum Perforatum L

St. John s Wort (SJW) or Hypericum perforatum L. is a therapeutic plant highly used in pharmacology. Recent in vivo anti-cancer action of naphtodianthrones (NTs) has extended the research related to enrichment methodologies of SJW phyto-extracts. Therefore, the presented study pursuits the optimization of single-step extraction methodologies to obtain NTs-rich extracts from SJW.

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