Deciphering the role of stress elicitors on the differential modulation of chalcone synthase gene and subsequent production of secondary metabolites in micropropagated Coelogyne ovalis Lindl., a therapeutically important medicinal orchid

2020 ◽  
Author(s):  
Nutan Singh ◽  
Suman Kumaria
Keyword(s):  
Secondary Metabolites ◽  
Chalcone Synthase ◽  
Differential Modulation ◽  
Chalcone Synthase Gene ◽  
Medicinal Orchid

scholarly journals Silencing of the chalcone synthase gene inCasuarina glaucahighlights the important role of flavonoids during nodulation

2013 ◽  
Vol 199 (4) ◽  
pp. 1012-1021 ◽  
Author(s):  
Khalid Abdel-Lateif ◽  
Virginie Vaissayre ◽  
Hassen Gherbi ◽  
Clotilde Verries ◽  
Emmanuelle Meudec ◽  
...  
Keyword(s):  
Chalcone Synthase ◽  
Chalcone Synthase Gene

Molecular Evolution of Chalcone Synthase Gene Superfamily in Plants

2015 ◽  
Vol 50 (1) ◽  
pp. 55
Author(s):  
Bao Ying ◽  
Guo Changfeng ◽  
Chen Shaohua ◽  
Liu Mei
Keyword(s):  
Molecular Evolution ◽  
Chalcone Synthase ◽  
Chalcone Synthase Gene

scholarly journals Exploring Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS

Toxins ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 133 ◽  
Author(s):  
Annika Jagels ◽  
Viktoria Lindemann ◽  
Sebastian Ulrich ◽  
Christoph Gottschalk ◽  
Benedikt Cramer ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Future Research ◽  
Structural Modifications ◽  
Metabolite Profiles ◽  
The Individual ◽  
First Time ◽  
Analytical Standards ◽  
Respective Species

The genus Stachybotrys produces a broad diversity of secondary metabolites, including macrocyclic trichothecenes, atranones, and phenylspirodrimanes. Although the class of the phenylspirodrimanes is the major one and consists of a multitude of metabolites bearing various structural modifications, few investigations have been carried out. Thus, the presented study deals with the quantitative determination of several secondary metabolites produced by distinct Stachybotrys species for comparison of their metabolite profiles. For that purpose, 15 of the primarily produced secondary metabolites were isolated from fungal cultures and structurally characterized in order to be used as analytical standards for the development of an LC-MS/MS multimethod. The developed method was applied to the analysis of micro-scale extracts from 5 different Stachybotrys strains, which were cultured on different media. In that process, spontaneous dialdehyde/lactone isomerization was observed for some of the isolated secondary metabolites, and novel stachybotrychromenes were quantitatively investigated for the first time. The metabolite profiles of Stachybotrys species are considerably influenced by time of growth and substrate availability, as well as the individual biosynthetic potential of the respective species. Regarding the reported adverse effects associated with Stachybotrys growth in building environments, combinatory effects of the investigated secondary metabolites should be addressed and the role of the phenylspirodrimanes re-evaluated in future research.

scholarly journals Biological Control and Mitigation of Aflatoxin Contamination in Commodities

Toxins ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 104
Author(s):  
Ferenc Peles ◽  
Péter Sipos ◽  
Szilvia Kovács ◽  
Zoltán Győri ◽  
István Pócsi ◽  
...  
Keyword(s):  
Biological Control ◽  
Secondary Metabolites ◽  
Competitive Exclusion ◽  
Aflatoxin Contamination ◽  
Post Harvest ◽  
Physical Chemical ◽  
Synthetic Chemicals ◽  
Ruminal Degradation

Aflatoxins (AFs) are toxic secondary metabolites produced mostly by Aspergillus species. AF contamination entering the feed and food chain has been a crucial long-term issue for veterinarians, medicals, agroindustry experts, and researchers working in this field. Although different (physical, chemical, and biological) technologies have been developed, tested, and employed to mitigate the detrimental effects of mycotoxins, including AFs, universal methods are still not available to reduce AF levels in feed and food in the last decades. Possible biological control by bacteria, yeasts, and fungi, their excretes, the role of the ruminal degradation, pre-harvest biocontrol by competitive exclusion or biofungicides, and post-harvest technologies and practices based on biological agents currently used to alleviate the toxic effects of AFs are collected in this review. Pre-harvest biocontrol technologies can give us the greatest opportunity to reduce AF production on the spot. Together with post-harvest applications of bacteria or fungal cultures, these technologies can help us strictly reduce AF contamination without synthetic chemicals.

Differential Modulation of MAP Kinases by Zinc Deficiency in IMR-32 Cells: Role of H2O2

2005 ◽  
Vol 7 (11-12) ◽  
pp. 1773-1782 ◽  
Author(s):  
M. Paola Zago ◽  
Gerardo G. Mackenzie ◽  
Ana M. Adamo ◽  
Carl L. Keen ◽  
Patricia I. Oteiza
Keyword(s):  
Zinc Deficiency ◽  
Map Kinases ◽  
Differential Modulation

scholarly journals Genome-wide miRNA analysis and integrated network for flavonoid biosynthesis in Osmanthus fragrans

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Yong Shi ◽  
Heng Xia ◽  
Xiaoting Cheng ◽  
Libin Zhang
Keyword(s):  
Secondary Metabolites ◽  
High Throughput Sequencing ◽  
Target Genes ◽  
Expression Profiles ◽  
Flavonoid Biosynthesis ◽  
Integrated Network ◽  
Osmanthus Fragrans ◽  
Flavonoid Synthesis ◽  
Genome Wide

AbstractBackgroundOsmanthus fragransis an important economical plant containing multiple secondary metabolites including flavonoids and anthocyanins. During the past years, the roles of miRNAs in regulating the biosynthesis of secondary metabolites in plants have been widely investigated. However, few studies on miRNA expression profiles and the potential roles in regulating flavonoid biosynthesis have been reported inO. fragrans.ResultsIn this study, we used high-throughput sequencing technology to analyze the expression profiles of miRNAs in leaf and flower tissues ofO. fragrans. As a result, 106 conserved miRNAs distributed in 47 families and 88 novel miRNAs were identified. Further analysis showed there were 133 miRNAs differentially expressed in leaves and flowers. Additionally, the potential target genes of miRNAs as well as the related metabolic pathways were predicted. In the end, flavonoid content was measured in flower and leaf tissues and potential role of miR858 in regulating flavonoid synthesis was illustrated inO. fragrans.ConclusionsThis study not only provided the genome-wide miRNA profiles in the flower and leaf tissue ofO. fragrans, but also investigated the potential regulatory role of miR858a in flavonoid synthesis inO. fragrans. The results specifically indicated the connection of miRNAs to the regulation of secondary metabolite biosynthesis in non-model economical plant.

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