Impact of severe mental illness on cancer stage at diagnosis and subsequent mortality: A population-based register study

2018 ◽  
Vol 201 ◽  
pp. 62-69 ◽  
Author(s):  
A. Toender ◽  
T. Munk-Olsen ◽  
M. Vestergaard ◽  
J.T. Larsen ◽  
N.P. Suppli ◽  
...  
2015 ◽  
Vol 25 (6) ◽  
pp. 966-972 ◽  
Author(s):  
Pegdwende O. Dialla ◽  
Patrick Arveux ◽  
Samiratou Ouedraogo ◽  
Carole Pornet ◽  
Aurélie Bertaut ◽  
...  

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Trang Nguyen ◽  
Thach Tran ◽  
Sally Green ◽  
Arthur Hsueh ◽  
Tuan Tran ◽  
...  

Abstract Background People with severe mental illness (SMI) living in low and middle-income countries can experience extended delays to diagnosis, which hinder access to medical treatment. The aims of this study were to describe the interval to diagnosis among these people in rural Vietnam and its associated factors. Methods A population-based cross-sectional study was conducted among people with SMI in two provinces in Vietnam. The delay to diagnosis was defined as the time between the first abnormal behaviour being observed by family members and the formal diagnosis of psychosis. A multilevel linear regression was used to examine the factors associated with the delay to diagnosis. Results Among 404 people with SMI from 370 households, the median delay to diagnosis was 11.5 months (IQR 0–168.0). Overall, 53.7% had a delay to diagnosis of less than one year (95% CI: 48.81–58.54). The financial burden of these people on their families was nearly USD 470/year. After adjusting for other factors at individual and household levels, living in a Northern province; older age, and having psychotic diagnosis before the implementation of the National Community Mental Health program (2003) were associated with a delay of more than twelve months to diagnosis. Conclusions These data indicate that the implementation of a national policy for community-based care has been effective in reducing the delay to diagnosis in rural Vietnam. Therefore, there is a need for strengthening the program and mental health policies, focusing on public communication to improve mental health literacy and reduce stigma against SMI.


2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 67s-67s
Author(s):  
R. Long ◽  
A. Woods ◽  
C. Biondi ◽  
J. Luzuriaga ◽  
C. Anderiesz ◽  
...  

Background: Stage at diagnosis is an important prognostic factor for cancer, providing contextual information for interpreting population health indicators such as mortality from cancer and cancer survival. Australian population-based cancer registries (PBCRs) routinely collect information on cancer incidence and mortality. The need for high quality, comprehensive national data on stage at diagnosis to supplement these data are widely recognized in Australia. The collection and dissemination of quality national stage data will enhance the: • ability to better monitor cancer outcomes, inform cancer control policy; • understand variations across different populations; and • identify where further research and targeted strategies may be required to improve cancer outcomes. Linking data on cancer stage at diagnosis with other administrative cancer data will also allow for a better understanding of the relationship between stage at diagnosis, treatments received, patterns of cancer recurrence, and survival outcomes. Aim: To strengthen national data capacity by collecting and reporting cancer stage at diagnosis for Cancer Australia's Stage, Treatment and Recurrence (STaR) project. Methods: Working with state and territory population-based cancer registries (PBCRs) and the Australian Pediatric Cancer Registry, Cancer Australia supported the development and testing of Business Rules for the collection of national cancer stage at diagnosis for: • The top 5 incident cancers based on the Tumor, Node, and Metastasis (TNM) staging system. These rules were endorsed by the Australasian Association of Cancer Registries (AACR) as a national standard in May 2016; and • Childhood cancers, with a separate set of Business Rules for 16 childhood cancer types based on the Toronto Pediatric Cancer Stage Guidelines. These rules were supported by the AACR as a national standard. Results: Using the AACR-endorsed Business Rules, comprehensive national cancer stage at diagnosis data for the top 5 incident cancers (for 2011) have been collected in Australia for the first time. Over 90% of incidence cases were able to be assigned a value for registry-derived (RD) stage at diagnosis for melanoma (97%), prostate (97%), and female breast (94%) cancers. Lower staging completeness was found for colorectal cancers (88%), and for lung cancers (72%). Business Rules for the collection of stage at diagnosis data for pediatric cancers have also been developed; 93% of sample cases diagnosed in the period 2006-2010 were able to be staged, ranging from 84% for nonrhabdomyosarcoma to 100% for hepatoblastoma. Conclusion: The Business Rules enabled the uniform collection of cancer stage at diagnosis data for the first time in Australia. The collection of these data will allow for the linkage of stage at diagnosis to other sources of information, including patterns of treatments applied, and enable reporting of survival and recurrence outcomes by stage.


2015 ◽  
Vol 172 (8) ◽  
pp. 776-783 ◽  
Author(s):  
Anette Riisgaard Ribe ◽  
Mogens Vestergaard ◽  
Wayne Katon ◽  
Morten Charles ◽  
Michael Eriksen Benros ◽  
...  

2018 ◽  
Vol 197 ◽  
pp. 298-304 ◽  
Author(s):  
Anne A.E. Thorup ◽  
Thomas Munk Laursen ◽  
Trine Munk-Olsen ◽  
Anne Ranning ◽  
Preben Bo Mortensen ◽  
...  

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S16-S17
Author(s):  
Anne Amalie Thorup ◽  
Kirstine Davidsen ◽  
Anne Ranning ◽  
Pia Jennes-Foli ◽  
Susanne Harder ◽  
...  

Abstract Background Children born to parents with severe mental illness like schizophrenia, bipolar disorder or recurrent major depression have been shown to have a higher risk, not only for developing a mental illness themselves in adulthood (Rasic) but also in childhood and adolescence. Less is known about the offspring’s somatic health and very early development processes. Increasing knowledge demonstrate the importance of the very early years of life from birth to age 6 for a healthy and natural brain development and for good life outcomes in general. Thus, more knowledge is needed about this vulnerable period in life, especially for children, who are born with a familial high risk for severe mental illness in order to develop relevant interventions for these children. Methods We used Danish registries to evaluate the incidence and the frequencies of early (i.e. age 0–6 years) psychiatric diagnoses of a nationwide cohort of children born to parents with severe mental illness. Further we calculated the frequencies of somatic health problems and compared them to population-based controls. Results We found increased ORs for children in all three FHR-groups for having received any diagnosis of a mental disorder before age 7 (e.g.: mother depressed, N=1223): OR:2.82 (CI:2.65–2.99), mother bipolar (N=98): OR: 3.06 (CI 2.50–3.76), mother schizophrenia (N=574): OR 5.23 (CI: 4.80–5.69), and similar although a bit smaller ORs if it was the father, who had a diagnosis. Especially ORs for attachment disorder and anxiety were increased but also ORs for eating disorders and sleep disorders were found to be significantly higher than for controls. Odd ratios for somatic disorders were marginally increased for all disorders and also for intoxications and injuries. Discussion Our results document that children born to parents with severe mental illnesses are vulnerable from the beginning of life, mainly in terms of their mental health but to some extent also in terms of somatic health. Parents who have a severe mental disorder may need extra support in the parenting role to ensure good health for the child.


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