Oncolytic viruses as a promising therapeutic strategy against the detrimental health impacts of air pollution: The case of glioblastoma multiforme

2021 ◽  
Author(s):  
Hamed Kazemi Shariat Panahi ◽  
Mona Dehhaghi ◽  
Su Shiung Lam ◽  
Wanxi Peng ◽  
Mortaza Aghbashlo ◽  
...  
Keyword(s):  
Air Pollution ◽  
Glioblastoma Multiforme ◽  
Therapeutic Strategy ◽  
Oncolytic Viruses ◽  
Health Impacts

Glioblastoma: Prognostic Factors and Predictive Response to Radio and Chemotherapy

2020 ◽  
Vol 27 (17) ◽  
pp. 2814-2825
Author(s):  
Francesco Fiorica ◽  
Maria Colella ◽  
Rosaria Taibi ◽  
Andrea Bonetti ◽  
Jacopo Giuliani ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Glioblastoma Multiforme ◽  
Poor Prognosis ◽  
Therapeutic Strategy ◽  
Biological Factors ◽  
Near Future ◽  
Predictive Response

: Glioblastoma multiforme (GBM) is characterized by poor prognosis despite an aggressive therapeutic strategy. In recent years, many advances have been achieved in the field of glioblastoma biology. : Here we try to summarize the main clinical and biological factors impacting clinical prognostication and therapy of GBM patients. From that standpoint, hopefully, in the near future, personalized therapies will be available.

scholarly journals Oncolytic viruses as a promising therapeutic strategy for hematological malignancies

2021 ◽  
Vol 139 ◽  
pp. 111573
Author(s):  
Chen Yang ◽  
Nanni Hua ◽  
Shufang Xie ◽  
Yi Wu ◽  
Lifeng Zhu ◽  
...  
Keyword(s):  
Therapeutic Strategy ◽  
Hematological Malignancies ◽  
Oncolytic Viruses

Health impacts of air pollution in China

2020 ◽  
Vol 15 (4) ◽  
Author(s):  
Fengping Hu ◽  
Yongming Guo
Keyword(s):  
Air Pollution ◽  
Health Impacts

Urban Municipal Solid Waste management: Modeling air pollution scenarios and health impacts in the case of Accra, Ghana

2021 ◽  
Vol 123 ◽  
pp. 15-22
Author(s):  
Gina Kanhai ◽  
Julius N. Fobil ◽  
Betty A. Nartey ◽  
Joseph V. Spadaro ◽  
Pierpaolo Mudu
Keyword(s):  
Air Pollution ◽  
Waste Management ◽  
Municipal Solid Waste ◽  
Solid Waste ◽  
Solid Waste Management ◽  
Health Impacts ◽  
Municipal Solid Waste Management

scholarly journals Health Impacts of Urban Bicycling in Mexico

2021 ◽  
Vol 18 (5) ◽  
pp. 2300
Author(s):  
David Rojas-Rueda
Keyword(s):  
Public Health ◽  
Physical Activity ◽  
Air Pollution ◽  
Health Risks ◽  
Health Benefits ◽  
Health Impacts ◽  
Traffic Fatalities ◽  
Premature Deaths ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Background: Bicycling has been associated with health benefits. Local and national authorities have been promoting bicycling as a tool to improve public health and the environment. Mexico is one of the largest Latin American countries, with high levels of sedentarism and non-communicable diseases. No previous studies have estimated the health impacts of Mexico’s national bicycling scenarios. Aim: Quantify the health impacts of Mexico urban bicycling scenarios. Methodology: Quantitative Health Impact Assessment, estimating health risks and benefits of bicycling scenarios in 51,718,756 adult urban inhabitants in Mexico (between 20 and 64 years old). Five bike scenarios were created based on current bike trends in Mexico. The number of premature deaths (increased or reduced) was estimated in relation to physical activity, road traffic fatalities, and air pollution. Input data were collected from national publicly available data sources from transport, environment, health and population reports, and surveys, in addition to scientific literature. Results: We estimated that nine premature deaths are prevented each year among urban populations in Mexico on the current car-bike substitution and trip levels (1% of bike trips), with an annual health economic benefit of US $1,897,920. If Mexico achieves similar trip levels to those reported in The Netherlands (27% of bike trips), 217 premature deaths could be saved annually, with an economic impact of US $45,760,960. In all bicycling scenarios assessed in Mexico, physical activity’s health benefits outweighed the health risks related to traffic fatalities and air pollution exposure. Conclusion: The study found that bicycling promotion in Mexico would provide important health benefits. The benefits of physical activity outweigh the risk from traffic fatalities and air pollution exposure in bicyclists. At the national level, Mexico could consider using sustainable transport policies as a tool to promote public health. Specifically, the support of active transportation through bicycling and urban design improvements could encourage physical activity and its health co-benefits.

High-Resolution Modelling of Health Impacts and Related External Cost from Air Pollution Using the Integrated Model System EVA

2016 ◽  
pp. 125-128
Author(s):  
Jørgen Brandt ◽  
Mikael Skou Andersen ◽  
Jakob Bønløkke ◽  
Jesper Heile Christensen ◽  
Kaj Mantzius Hansen ◽  
...  
Keyword(s):  
Air Pollution ◽  
High Resolution ◽  
Integrated Model ◽  
Model System ◽  
Health Impacts ◽  
External Cost

scholarly journals Assessing the health impacts of electric vehicles through air pollution in the United States

2020 ◽  
Vol 144 ◽  
pp. 106015
Author(s):  
Ernani F. Choma ◽  
John S. Evans ◽  
James K. Hammitt ◽  
José A. Gómez-Ibáñez ◽  
John D. Spengler
Keyword(s):  
United States ◽  
Air Pollution ◽  
Electric Vehicles ◽  
The United States ◽  
Health Impacts

scholarly journals Health and Economic Impacts Assessment of O3 Exposure in Mexico

2021 ◽  
Vol 18 (21) ◽  
pp. 11646
Author(s):  
José Texcalac-Sangrador ◽  
Magali Hurtado-Díaz ◽  
Eunice Félix-Arellano ◽  
Carlos Guerrero-López ◽  
Horacio Riojas-Rodríguez
Keyword(s):  
Air Pollution ◽  
Economic Valuation ◽  
Ambient Air ◽  
Health Impact ◽  
Ambient Air Pollution ◽  
World Health ◽  
Health Impacts ◽  
Uncertainty Interval ◽  
Avoidable Deaths

Health effects related to exposure to air pollution such as ozone (O3) have been documented. The World Health Organization has recommended the use of the Sum of O3 Means Over 35 ppb (SOMO35) to perform Health Impact Assessments (HIA) for long-term exposure to O3. We estimated the avoidable mortality associated with long-term exposure to tropospheric O3 in 14 cities in Mexico using information for 2015. The economic valuation of avoidable deaths related to SOMO35 exposure was performed using the willingness to pay (WTP) and human capital (HC) approaches. We estimated that 627 deaths (95% uncertainty interval (UI): 227–1051) from respiratory diseases associated with the exposure to O3 would have been avoided in people over 30 years in the study area, which confirms the public health impacts of ambient air pollution. The avoidable deaths account for almost 1400 million USD under the WTP approach, whilst the HC method yielded a lost productivity estimate of 29.7 million USD due to premature deaths. Our findings represent the first evidence of the health impacts of O3 exposure in Mexico, using SOMO35 metrics.

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