Dynamic simulation of multicomponent gas separation by hollow-fiber membrane module: Nonideal mixing flows in permeate and residue sides using the tanks-in-series model

2011 ◽  
Vol 76 (3) ◽  
pp. 362-372 ◽  
Author(s):  
Takashi Katoh ◽  
Masahiro Tokumura ◽  
Hidemi Yoshikawa ◽  
Yoshinori Kawase
AIChE Journal ◽  
1998 ◽  
Vol 44 (6) ◽  
pp. 1289-1302 ◽  
Author(s):  
D. T. Coker ◽  
B. D. Freeman ◽  
G. K. Fleming

2014 ◽  
Vol 625 ◽  
pp. 726-729 ◽  
Author(s):  
Serene Sow Mun Lock ◽  
Kok Keong Lau ◽  
Mohd Shariff Azmi

A “Multi-component Progressive Cell Balance” approach has been applied to characterize the gas separation of the radial crossflow hollow fiber membrane module. The mathematical model is an indispensable tool to evaluate the separation performance of membrane material towards different components. The approach is required to be implemented since there is scarcely available mathematical model to characterize the two dimensional radial crossflow. In addition, the currently available mathematical model is confined to the ideal binary system, which constraints its applicability in real membrane separation process with many components. The significance of the developed multi-component mathematical model as compared to the model adapting the ideal binary simulation condition is demonstrated in this study.


2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Shinji Hayashi ◽  
Rieko Yagi ◽  
Shuhei Taniguchi ◽  
Masami Uji ◽  
Hidaka Urano ◽  
...  

AbstractCell-assisted lipotransfer (CAL) is an advanced lipoinjection method that uses autologous lipotransfer with addition of a stromal vascular fraction (SVF) containing adipose-derived stromal stem cells (ASCs). The CAL procedure of manual isolation of cells from fat requires cell processing to be performed in clean environment. To isolate cells from fat without the need for a cell processing center, such as in a procedure in an operation theater, we developed a novel method for processing SVF using a closed cell washing concentration device (CCD) with a hollow fiber membrane module. The CCD consists of a sterilized closed circuit, bags and hollow fiber, semi-automatic device and the device allows removal of >99.97% of collagenase from SVF while maintaining sterility. The number of nucleated cells, ASCs and viability in SVF processed by this method were equivalent to those in SVF processed using conventional manual isolation. Our results suggest that the CCD system is as reliable as manual isolation and may also be useful for CAL. This approach will help in the development of regenerative medicine at clinics without a cell processing center.


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