Supercritical fluid extraction of Eucalyptus globulus leaves. Experimental and modelling studies of the influence of operating conditions and biomass pretreatment upon yields and kinetics

Supercritical fluid extraction (SFE) is one of the relatively new efficient separation method for the extraction of essential oils from different plant materials. The new products, extracts, can be used as a good base for the production of pharmaceutical drugs and additives in the perfume, cosmetic, and food industries. The aim of this work was to analyze the supercritical carbon dioxide extraction (SC-CO2) of oils from the selected spice plant materials. In this paper the process parameters such as pressure, temperature, solvent flow rate, size of grinding materials, and ratio of the co-solvent were presented for the selected spice plant materials: black pepper, caraway, celery, cinnamon, clove, coriander, daphne, fennel, ginger, hyssop, juniper, lavender, oregano, pennyroyal, red pepper, safflower, sage, turmeric, and vanilla. The values of operating conditions were: pressure from 7.5 to 68 MPa, temperature from 293 to 363 K, solvent flow rate from 0.003 to 30.0 kg/h, and diameter of grinding material from 0.17 to 3.90 mm. The global yield and quality of the extracts all of the plant material investigated, as well as the possibility of their application in the food, cosmetics and pharmaceutical industries were analyzed. The composition of the extracts was wery complex, and in every case the extract was composed of more than 200 components. All the compounds from the CO2 extracts were classified in the following groups: monoterpene, sesquiterpene, oxygenated monoterpene, and oxygenated sesquiterpene and other hydrocarbon groups. In some of the systems investigated the different mathematical models (Sovová, Hong), which have taken from the literature, were used to correlate the experimental data.

Download Full-text

Effect of Static Extraction Time on Supercritical Fluid Extraction of Bioactive Compounds from Phyllanthus niruri

Journal of Computational and Theoretical Nanoscience ◽

10.1166/jctn.2020.8742 ◽

2020 ◽

Vol 17 (2) ◽

pp. 918-924 ◽

Cited By ~ 1

Author(s):

Norsyamimi Hassim ◽

Masturah Markom ◽

Masli Irwan Rosli ◽

Shuhaida Harun

Keyword(s):

Supercritical Fluid Extraction ◽

Supercritical Fluid ◽

Bioactive Compounds ◽

Total Content ◽

Operating Conditions ◽

Extraction Time ◽

Fluid Extraction ◽

Active Components ◽

Phyllanthus Niruri ◽

Static Extraction

Supercritical fluid extraction (SFE) is an effective method to extract active components from plants. SFE process can be conducted by using a static or/and dynamic extraction. Static extraction is important for the diffusion of solvated analyte to the matrix surface. Therefore, the main objective of this study is to evaluate the static extraction time influence on SFE extraction of Phyllanthus niruri and the main bioactive compounds. The extraction was conducted by using supercritical carbon dioxide (SC-CO2) with 50% ethanol-water as a co-solvent at selected operating conditions (200 bar, 60 °C, 10% co-solvent content and 3 ml/min solvent total flow rate). The static extraction time was investigated in the range of 15 min–75 min by allowing the plant matrix to immerse in a mixture of SC-CO2 and 50% ethanol-water at the operating condition. The quantification of targeted compounds, which were gallic acid (GA), corilagin (CO) and ellagic acid (EA) were analysed by using high performance liquid chromatography (HPLC). The observation on the physical characteristics of the plant matrix was performed by using the scanning electron microscopy (SEM). The best result for total extraction yield was obtained at 60 min of static extraction time, which was 20.7% g/g sample. It also gave a better result for all three targeted compounds in terms of total content percentage (0.35% g GA/g extract, 3.05% g CO/g extract, and 5.17% g EA/g extract). In conclusion, static extraction time was crucial in extracting bioactive compounds in P. niruri by using SFE method and should be considered as the main parameter other than pressure and temperature.

Download Full-text