scholarly journals The relationship between obstructive sleep apnea and insomnia: a population-based cross-sectional polysomnographic study

2019 ◽  
Vol 54 ◽  
pp. 126-133 ◽  
Author(s):  
B.L. Uhlig ◽  
K. Hagen ◽  
M. Engstrøm ◽  
M. Stjern ◽  
G.B. Gravdahl ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Population Based ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Relationship

Depressive Symptoms in Comorbid Obstructive Sleep Apnea and Insomnia: An Integrative Review

2021 ◽  
pp. 019394592198965
Author(s):  
Bomin Jeon ◽  
Faith S. Luyster ◽  
Judith A. Callan ◽  
Eileen R. Chasens
Keyword(s):  
Obstructive Sleep Apnea ◽  
Depressive Symptoms ◽  
Sleep Apnea ◽  
Control Design ◽  
Case Control ◽  
Integrative Review ◽  
Study Quality ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Relationship

The purpose of this integrative review was to synthesize evidence concerning the relationship between comorbid obstructive sleep apnea and insomnia (OSA+I), and depressive symptoms. OSA and insomnia are common sleep disorders, recently comorbid OSA+I has been recognized as prevalent in adults. Although each sleep disorder increases the risk and severity of depressive symptoms, the effect of comorbid OSA+I on depressive symptoms remains unclear. A systematic search of PubMed, CINAHL, and PsycINFO identified 15 data-based studies. All the studies were observational with either a cross-sectional (n = 14) or a case-control design (n = 1). Study quality was assessed. Most of the studies (n = 14) indicated that comorbid OSA+I had an additive role on depressive symptoms. Insomnia appeared to have a more important role than OSA in increasing the severity of depressive symptoms in persons with comorbid OSA+I.

scholarly journals Obstructive Sleep Apnea among the Lebanese general population: Prevalence, associated factors and knowledge

2020 ◽  
Author(s):  
Aurélie Choucair ◽  
Diana Malaeb ◽  
Souheil Hallit ◽  
Elissar Dagher
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Daytime Sleepiness ◽  
Associated Factors ◽  
Public Awareness ◽  
Large Population ◽  
Population Based ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Study Results

Abstract Background : To date, there has been no large population-based study associated with public awareness in Lebanon about sleep apnea. Our study investigated the prevalence of, associated factors and knowledge of Obstructive Sleep Apnea (OSA) among a representative sample of Lebanese adults. Methods: A cross-sectional study, conducted between June and August 2019, enrolled 472 people aged above 18 years. A proportionate random sample from all Lebanese Mohafazat was applied. Results: The study results showed that a higher number of cigarettes per day, having diabetes mellitus, myocardial infarction, hypertension and arrhythmia were associated with higher daytime sleepiness. Participants living in the North had less daytime sleepiness, whereas those living in Beqaa had higher daytime sleepiness compared to those living in Beirut. Concerning knowledge, having heard about sleep apnea and having a university level of education were associated with a higher score, whereas having cerebrovascular accidents was associated with lower knowledge scores. Conclusion Complications of OSA are still poorly known, as are certain suggestive symptoms. Given the local relevance of OSA, ongoing health campaigns and innovative educational programs should be assigned to target the general community.

scholarly journals The Relationship between Obstructive Sleep Apnea (OSA) and Adherence of Antihypertensive Consumption in Regular Hemodialysis Patient

2019 ◽  
Vol 2 (2) ◽  
pp. 96-103
Author(s):  
Afrilia Rosada Lubis ◽  
Riri Andri Muzasti
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Antihypertensive Drugs ◽  
Cross Sectional Study ◽  
Secondary Hypertension ◽  
Drug Consumption ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Relationship

Background. Based on the Indonesian Renal Registry (IRR) data in 2015, the highest incidence of comorbidities in hemodialysis patients in Indonesia was hypertension (50%). Obstructive Sleep Apnea (OSA) is one of the causes of secondary hypertension, the characteristics of hypertension in OSA are more resistant to treatment. One of the causes of resistant hypertension is patient non-compliance with the consumption of antihypertensive drugs. Aim. To determine the relationship of adherence of consumption of antihypertensive drugs with obstructive sleep apnea in regular HD patients. Method. This cross-sectional study involved 89 outpatients in HD units at the Rasyida Kidney Hospital in 2018. Data was obtained through interview using the STOP-BANG questionnaire to assess the of risk of OSA and using Morisky Medication Adherence Scale (MMAS) questionnaire to measure the compliance of  drug consumption. Results.The prevalence of OSA  in HD patients was (39.3%). There was no significant relationship between adherence with drug consumption and OSA risk, but in bivariate analysis, age (p = 0.0001), body mass index (BMI) (p = 0.001), and gender (p = 0.03) were significantly related to OSA. In multivariate, age and BMI were significantly associated with OSA (OR: 6.449, 95% CI 2.246 ± 18.520, p = 0.001; OR: 6.130, 95% CI 2.105 ± 17.849, p = 0.001). Conclusion. OSA was not statistically related to adherence to antihypertensive drug consumption in HD patients but was significantly associated with age and BMI.     Keyword. Adherence to antihypertensive consumption, hemodialysis, obstructive sleep apnea.

Interaction of cross-sectional area, driving pressure, and airflow of passive velopharynx

1997 ◽  
Vol 83 (3) ◽  
pp. 851-859 ◽  
Author(s):  
Shiroh Isono ◽  
Thom R. Feroah ◽  
Eric A. Hajduk ◽  
Rollin Brant ◽  
William A. Whitelaw ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Positive Airway Pressure ◽  
Cross Sectional Area ◽  
Driving Pressure ◽  
Sectional Area ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Pharyngeal Muscles ◽  
The Relationship

Isono, Shiroh, Thom R. Feroah, Eric A. Hajduk, Rollin Brant, William A. Whitelaw, and John E. Remmers. Interaction of cross-sectional area, driving pressure, and airflow of passive velopharynx. J. Appl. Physiol. 83(3): 851–859, 1997.—Previous studies have shown that, when the pharyngeal muscles are relaxed, the velopharynx is a highly compliant segment of the pharynx. Thus, under these circumstances, cross-sectional area of the velopharynx ( A VP), driving pressure across the velopharynx (ΔP), and inspiratory airflow (V˙i) will be mutually interdependent variables. The purpose of the present investigation was to describe the interrelation among these three variables during inspiration. We studied 15 sleeping patients with obstructive sleep apnea/hypopnea when the pharyngeal muscles were rendered hypotonic by applying continuous positive airway pressure to the nasal airway. A VP, determined by endoscopic imaging, was significantly greater at onset ofV˙i limitation than at minimum oropharyngeal pressure ( P < 0.01). Snoring was never observed duringV˙ilimitation. In a subgroup of six patients, values for ΔP,V˙i, and A VP were obtained at 0.1-s intervals at various levels of mask pressure. For these six patients, the mathematical expressionV˙i = 0.657( A VP/ A max) ⋅ ΔP0.332, where A max is maximal A VP, described the relationship among the three variables ( R 2 = 0.962) for flow-limited and non-flow-limited inspirations. The impedance of the passive velopharynx, defined as ΔP0.33/V˙, was inversely related to A VP and increased dramatically when A VP was <0.3 cm2. In summary, we observed a progressive decrease in A VP during flow-limited inspiration in patients with obstructive sleep apnea. This constriction of the velopharynx contributes to an increase in velopharyngeal impedance that, in turn, counterbalances the increase in ΔP during flow limitation.

scholarly journals Obstructive Sleep Apnea and the Subsequent Risk of Chronic Rhinosinusitis: A Population-Based Study

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Li-Ting Kao ◽  
Shih-Han Hung ◽  
Herng-Ching Lin ◽  
Chih-Kuang Liu ◽  
Hung-Meng Huang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Chronic Rhinosinusitis ◽  
Population Based ◽  
Study Cohort ◽  
Population Based Study ◽  
Cox Proportional Hazard ◽  
Obstructive Sleep ◽  
Cox Proportional Hazard Regression ◽  
The Relationship

Abstract The relationship between obstructive sleep apnea (OSA) and chronic rhinosinusitis (CRS) still remains unclear. This retrospective cohort study aimed to investigate the relationship between OSA and subsequent CRS using a population-based dataset. The study used data from the Taiwan Longitudinal Health Insurance Database 2005. We selected 971 patients with OSA for the study cohort and 4855 patients without OSA for the comparison cohort. Each patient was tracked for 5 years to determine those who were subsequently diagnosed with CRS. Stratified Cox proportional hazard regression analyses were performed to examine the association of OSA with subsequent CRS. The results revealed that 161 (2.76%) of the total sampled patients were subsequently diagnosed with CRS. Subsequent incidences of CRS were found in 64 (6.59%) patients with OSA and 97 (2.00%) patients without OSA. The adjusted hazard ratio (HR) of subsequent CRS for patients with OSA was 3.18 (95% confidence interval: 2.27~4.45) compared to those without OSA. Furthermore, the HR for CRS was similar for subjects with OSA for both genders (with an adjusted HR of 3.44 for males and 2.63 for females). We concluded that patients with OSA had a higher risk of subsequent CRS compared to patients without OSA regardless of sex.

scholarly journals The relationship between metabolic syndrome and obstructive sleep apnea syndrome: a nationwide population-based study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Do Hyun Kim ◽  
Bongseong Kim ◽  
Kyungdo Han ◽  
Soo Whan Kim
Keyword(s):  
Metabolic Syndrome ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Population Based ◽  
Confounding Factors ◽  
Obstructive Sleep ◽  
Apnea Syndrome ◽  
The Relationship

AbstractThere has been a need for research on the association between metabolic syndrome (MetS) and obstructive sleep apnea syndrome (OSAS) using large data such as nationwide population-based data that adjusts important confounding factors. Therefore, we investigated the relationship between MetS and OSAS. The data source we used was the National Health Insurance Service claims database managed by the Republic of Korea government, in which 10,113,560 individuals were enrolled in 2009 and followed up until 2018. The independent association of MetS with the risk of OSAS was determined using a Cox proportional hazards model with adjustment for age, sex, smoking status, alcohol consumption, regular physical exercise, and body mass index. Our results showed that MetS were strongly associated to OSAS which was adjusted for several confounding factors. Also, we found men, increased waist circumference and increased triglyceride are important risk factors for OSAS.

Nasal Patency and the Effectiveness of Nasal Continuous Positive Air Pressure in Obstructive Sleep Apnea

1998 ◽  
Vol 118 (5) ◽  
pp. 643-647 ◽  
Author(s):  
Gary L. Schechter ◽  
J. Catesby Ware ◽  
James Perlstrom ◽  
Reuben H. Mcbrayer
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Acoustic Rhinometry ◽  
Air Pressure ◽  
Apnea Hypopnea Index ◽  
Nasal Patency ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Relationship ◽  
Head Neck

Nasal airway obstruction may exacerbate sleep apnea and is difficult to quantify on clinical examination. In this study, we examined the relationship among nasal patency, the frequency of sleep apnea events, and effective nasal continuous positive air pressures. Acoustic rhinometry was used as an objective measurement of nasal cross-sectional areas in 76 patients without nasal symptoms who underwent study with diagnostic polysomnography because of obstructive sleep apnea. Patients with persistent obstructive sleep apnea were titrated to nasal continuous positive air pressure in a split night study. All subjects had a mean apnea/hypopnea index of 28, and those with obstructive sleep apnea had a mean apnea/hypopnea index of 43. Mean cross-sectional areas 1 to 4 cm into the nose were 1.7, 1.1, 2.1, and 2.8 cm 2 , respectively (F = 39, p < 0.001). However, there was no correlation between the apnea/hypopnea index and the cross-sectional area at the four distances (r = 0.03, 0.06, 0.02, and 0.02, respectively, p = not significant). Correlations between nasal continuous positive air pressures and cross-sectional areas did not reveal a significant relationship at any of the four sites (r = 0.09, 0.07, −0.03, 0.00, respectively). Findings in patients with apnea were also compared with those in patients without apnea and significant differences were not found (F = 0.019, p = not significant). Although it would seem intuitive that increased nasal obstruction is associated with the severity of obstructive sleep apnea and difficulty with the use of nasal continuous positive air pressure, this study shows that nasal patency, as measured by acoustic rhinometry, does not correlate with the severity of obstructive sleep apnea, as determined by the apnea/hypopnea index or the effective nasal continuous positive air pressure. (Otolaryngol Head Neck Surg 1998;118:643–7.)

scholarly journals Assessment of the relationship between metabolic syndrome and obstructive sleep apnea in male drivers of Shahroud city in 2018: a cross sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Mina Shayestefar ◽  
Khosro Sadeghniiat Haghighi ◽  
Shayesteh Jahanfar ◽  
Mehri Delvarianzadeh ◽  
Farzaneh Nematzadeh ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Relationship

scholarly journals The association between obstructive sleep apnea and sleep spindles in middle-aged and older men: A community-based cohort study

SLEEP ◽  
2021 ◽  
Author(s):  
Jesse L Parker ◽  
Yohannes Adama Melaku ◽  
Angela L D’Rozario ◽  
Gary A Wittert ◽  
Sean A Martin ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Morphological Changes ◽  
Large Population ◽  
Population Based ◽  
Community Dwelling ◽  
Apnea Hypopnea Index ◽  
Sleep Spindles ◽  
Cross Sectional ◽  
Obstructive Sleep

Abstract Study objectives Sleep spindles show morphological changes in obstructive sleep apnea (OSA). However, previous small studies have limited generalisability, leaving associations between OSA severity measures and spindle metrics uncertain. This study examined cross-sectional associations between OSA severity measures and spindle metrics among a large population-based sample of men. Methods Community-dwelling men with no previous OSA diagnosis underwent home-based polysomnography. All-night EEG (F4-M1) recordings were processed for artefacts and spindle events identified using previously validated algorithms. Spindle metrics of interest included frequency (Hz), amplitude (µV 2), overall density (11–16 Hz), slow density (11–13 Hz), and fast density (13–16 Hz) (number/minute). Multivariable linear regression models controlling for demographic, biomedical, and behavioural confounders were used to examine cross-sectional associations between OSA severity measures and spindle metrics. Results In adjusted analyses, higher apnea-hypopnea index (AHI/h, as a continuous variable) and percentage total sleep time with oxygen saturation &lt;90% (TST90) were associated with decreased slow spindle density (AHI, B= -0.003, p=0.032; TST90, B= -0.004, p=0.047) but increased frequency (AHI, B=0.002, p=0.009; TST90, B=0.002, p=0.043). Higher TST90 was also associated with greater spindle amplitude (N2 sleep, B=0.04, p=0.011; N3 sleep, B=0.11, p&lt;0.001). Furthermore, higher arousal index was associated with greater spindle amplitude during N2 sleep (B=0.31, p&lt;0.001) but decreased overall density (B= -1.27, p=0.030) and fast density (B= -4.36, p=0.028) during N3 sleep. Conclusions Among this large population-based sample of men, OSA severity measures were independently associated with spindle abnormalities. Further population studies are needed to determine associations between spindle metrics and functional outcomes.

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