scholarly journals Obstructive Sleep Apnea among the Lebanese general population: Prevalence, associated factors and knowledge

2020 ◽  
Author(s):  
Aurélie Choucair ◽  
Diana Malaeb ◽  
Souheil Hallit ◽  
Elissar Dagher
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Daytime Sleepiness ◽  
Associated Factors ◽  
Public Awareness ◽  
Large Population ◽  
Population Based ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Study Results

Abstract Background : To date, there has been no large population-based study associated with public awareness in Lebanon about sleep apnea. Our study investigated the prevalence of, associated factors and knowledge of Obstructive Sleep Apnea (OSA) among a representative sample of Lebanese adults. Methods: A cross-sectional study, conducted between June and August 2019, enrolled 472 people aged above 18 years. A proportionate random sample from all Lebanese Mohafazat was applied. Results: The study results showed that a higher number of cigarettes per day, having diabetes mellitus, myocardial infarction, hypertension and arrhythmia were associated with higher daytime sleepiness. Participants living in the North had less daytime sleepiness, whereas those living in Beqaa had higher daytime sleepiness compared to those living in Beirut. Concerning knowledge, having heard about sleep apnea and having a university level of education were associated with a higher score, whereas having cerebrovascular accidents was associated with lower knowledge scores. Conclusion Complications of OSA are still poorly known, as are certain suggestive symptoms. Given the local relevance of OSA, ongoing health campaigns and innovative educational programs should be assigned to target the general community.

scholarly journals Obstructive Sleep Apnea: Evaluation of high risk individuals, knowledge and associated factors among a representative sample of Lebanese adults

2020 ◽  
Author(s):  
Aurélie Choucair ◽  
Diana Malaeb ◽  
Souheil Hallit ◽  
Elissar Dagher
Keyword(s):  
Myocardial Infarction ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
High Risk ◽  
Daytime Sleepiness ◽  
Representative Sample ◽  
Associated Factors ◽  
Diabetic Patients ◽  
Obstructive Sleep ◽  
Study Results

Abstract Background: To date, there has been no large population-based study about Obstructive Sleep Apnea (OSA) in Lebanon. Our study evaluated high risk individuals, knowledge and associated factors of OSA among a representative sample of Lebanese adults. Methods: A cross-sectional study, conducted between June and August 2019, enrolled 472 people aged above 18. A proportionate random sample from all Lebanese Governorate was applied. Each governorate is divided into Caza (stratum), which in turn is divided into multiple villages. Two villages were selected randomly from the list of villages provided by the Central Agency of Statistics in Lebanon. Households were randomly selected from each village using an online software.Results: The percentage of physician-diagnosed sleep apnea in our sample was 11%; 159 (33.7%) had poor knowledge (scores ≤11), whereas 165 (35.0%) and 148 (31.4%) had moderate (scores between 12 and 15) and good (scores ≥16) knowledge respectively. The study results showed that -according to the Epworth Scale- having diabetes mellitus, myocardial infarction, arrhythmia, and hypertension were associated with higher daytime sleepiness. Furthermore, mild, moderate and severe excessive daytime sleepiness (EDS) percentages were 14.4%, 16.3% and 13.8% respectively. According to the STOP-BANG questionnaire, 31.6% of participants had an intermediate risk of OSA and 7.6% had a high risk. Diabetic patients and those with myocardial infarction were significantly associated with higher STOP BANG scores.Concerning knowledge, having heard about sleep apnea was associated with a higher knowledge score. Overall, 31.4% of the participants had a good score. Conclusion The actual study proves that EDS which has adverse health effects, is associated with multiple morbidities. Besides, the general population isn’t aware enough of this disease. Comparing the rate of high-risk individuals to the physician-diagnosed ones, we conclude that in Lebanon, OSA is likely prevalent but underdiagnosed. Ongoing health campaigns and screenings should be assigned to target the general community.

scholarly journals The association between obstructive sleep apnea and sleep spindles in middle-aged and older men: A community-based cohort study

SLEEP ◽  
2021 ◽  
Author(s):  
Jesse L Parker ◽  
Yohannes Adama Melaku ◽  
Angela L D’Rozario ◽  
Gary A Wittert ◽  
Sean A Martin ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Morphological Changes ◽  
Large Population ◽  
Population Based ◽  
Community Dwelling ◽  
Apnea Hypopnea Index ◽  
Sleep Spindles ◽  
Cross Sectional ◽  
Obstructive Sleep

Abstract Study objectives Sleep spindles show morphological changes in obstructive sleep apnea (OSA). However, previous small studies have limited generalisability, leaving associations between OSA severity measures and spindle metrics uncertain. This study examined cross-sectional associations between OSA severity measures and spindle metrics among a large population-based sample of men. Methods Community-dwelling men with no previous OSA diagnosis underwent home-based polysomnography. All-night EEG (F4-M1) recordings were processed for artefacts and spindle events identified using previously validated algorithms. Spindle metrics of interest included frequency (Hz), amplitude (µV 2), overall density (11–16 Hz), slow density (11–13 Hz), and fast density (13–16 Hz) (number/minute). Multivariable linear regression models controlling for demographic, biomedical, and behavioural confounders were used to examine cross-sectional associations between OSA severity measures and spindle metrics. Results In adjusted analyses, higher apnea-hypopnea index (AHI/h, as a continuous variable) and percentage total sleep time with oxygen saturation <90% (TST90) were associated with decreased slow spindle density (AHI, B= -0.003, p=0.032; TST90, B= -0.004, p=0.047) but increased frequency (AHI, B=0.002, p=0.009; TST90, B=0.002, p=0.043). Higher TST90 was also associated with greater spindle amplitude (N2 sleep, B=0.04, p=0.011; N3 sleep, B=0.11, p<0.001). Furthermore, higher arousal index was associated with greater spindle amplitude during N2 sleep (B=0.31, p<0.001) but decreased overall density (B= -1.27, p=0.030) and fast density (B= -4.36, p=0.028) during N3 sleep. Conclusions Among this large population-based sample of men, OSA severity measures were independently associated with spindle abnormalities. Further population studies are needed to determine associations between spindle metrics and functional outcomes.

scholarly journals GCH1 (rs841) polymorphism in the nitric oxide-forming pathway has protective effects on obstructive sleep apnea

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Samaneh Sheikhi Kouhsar ◽  
Mohammadreza Bigdeli ◽  
Yadollah Shakiba ◽  
Khosro Sadeghniiat
Keyword(s):  
Nitric Oxide ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Daytime Sleepiness ◽  
Genetic Factors ◽  
Protective Effects ◽  
No Formation ◽  
Obstructive Sleep ◽  
Study Results ◽  
Reverse Relationship

AbstractSeveral studies have recently investigated the contribution of genetic factors in obstructive sleep apnea (OSA). Patients with OSA suffer from a reduction in nitric oxide (NO) serum level. This study investigated rs841, A930G p22phox, and rs1799983 polymorphisms in three critical genes involved in NO formation. A total of 94 patients with OSA and 100 healthy controls were enrolled into the study. Results showed there was no association between rs841, A930G p22phox and rs1799983 polymorphism and the risk of OSA (P = 0.51, P = 0.4 and P = 0.33, respectively). Moreover, rs841 GA genotype had a reverse relationship with the severity of OSA (P = 0.005). On the other hand, rs841 GA and A930G p22phox AA genotypes had a protective effect on daytime sleepiness in OSA patients (P = 0.01and P = 0.02, respectively). Additionally, the combination of rs841 and A930G p22phox (AG/AG and AG/AA) genotypes was significantly associated with a reduction in daytime sleepiness in OSA patients (P = 0.03 and P = 0.03, respectively). According to the results of our study, GA genotype of rs841 and GA/AA genotypes of A930G p22phox polymorphisms significantly reduced the severity of the problem and daytime sleepiness in OSA patients.

scholarly journals Excessive daytime sleepiness and obstructive sleep apnea among aircrew: A questionnaire survey

2019 ◽  
Vol 63 ◽  
pp. 16-20
Author(s):  
HMK Murthy ◽  
SS Mohapatra
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
General Population ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
Prevalence Rate ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstructive Sleep

Background: Obstructive sleep apnea (OSA) is a condition resulting in disrupted sleep and excessive daytime sleepiness/somnolence (EDS) with demonstrable deficits in cognitive and psychomotor performance. Indian studies have shown the prevalence of 4.9–19.7% in males and 2.1–7.4% in females. Prevalence among military aviators is unknown. Materials and Methods: EDS was determined by employing Epworth Sleepiness Scale (ESS) among the 54 male aircrews in an airbase. The risk for OSA was also determined among these individuals using STOP-BANG questionnaire. Results and Discussion: It was found that none of the aircrews in the study group is found to have dangerously sleepy (DS). About 11.11% of the studied population were found to have EDS which is less than the prevalence rate in India as per a study conducted by the National Institute of Mental Health and Neuro Sciences on general population and the Western world (prevalence rate of 16.7%) as found by Gislason et al. OSA risk among the study population was (n = 9/54) 16.16%. The prevalence of OSA in India male is reported as 4.9–17.9%. Thus, percentage of aircrew showing the risk for OSA in this cross-sectional study is comparable with the general population in India. However, no correlation was found between the risk factors of OSA with ESS. The reasons for EDS could be attributed to factors such as personal lifestyle, sleeping habits, and poor work-rest schedules. It is interesting to note that none of the aircrew, who is positive for OSA risk, is showing EDS/DS. This further confirms that OSA risk individuals may not have EDS/DS and this could be a reason why, OSA largely remains underdiagnosed and untreated in clinical practice. Conclusion: This cross-sectional study has brought the conclusion that both EDS and risk for OSA coexists even in a fit and healthy population of aircrew.

scholarly journals The relationship between obstructive sleep apnea and insomnia: a population-based cross-sectional polysomnographic study

2019 ◽  
Vol 54 ◽  
pp. 126-133 ◽  
Author(s):  
B.L. Uhlig ◽  
K. Hagen ◽  
M. Engstrøm ◽  
M. Stjern ◽  
G.B. Gravdahl ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Population Based ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Relationship

scholarly journals Obstructive sleep apnea in Norwegian adults with achondroplasia: a population-based study

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Svein O. Fredwall ◽  
Britt Øverland ◽  
Hanne Berdal ◽  
Søren Berg ◽  
Harald Weedon-Fekjær ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Clinical Symptoms ◽  
Population Based ◽  
Cross Sectional Study ◽  
Apnea Hypopnea Index ◽  
Berlin Questionnaire ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Sleep Registration

Abstract Background Previous studies have found a high prevalence of obstructive sleep apnea (OSA) in children with achondroplasia, but clinical studies on this complication in adults with achondroplasia are lacking. Objectives This population-based, cross-sectional study investigated the prevalence, severity, and predictive factors of OSA in Norwegian adults with achondroplasia. Methods We collected clinical data on 49 participants. Participants without a preexisting diagnosis of OSA had an overnight sleep registration. OSA was defined as an apnea–hypopnea index (AHI) ≥ 5 plus characteristic clinical symptoms, or AHI ≥ 15. We used the Berlin Questionnaire to assess clinical symptoms of OSA. Results OSA was found in 59% (29/49) of the participants (95% confidence interval 44 to 73%), of whom 59% (17/29) had moderate to severe OSA (AHI ≥ 15), and 48% (14/29) were previously undiagnosed. Variables predictive of OSA were: excessive daytime sleepiness; unrested sleep; loud snoring; observed nocturnal breathing stops; hypertension; age > 40 years; and BMI > 30 kg/m2. Conclusion OSA was highly prevalent in Norwegian adults with achondroplasia, which we believe is representative of this population worldwide. Follow-up of adults with achondroplasia should include assessment of symptoms and signs of OSA, with a low threshold for conducting an overnight sleep registration if findings suggestive of OSA are present.

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