scholarly journals Corrigendum to “Fully supercritical CO2 preparation of a nanostructured MOF composite with application in cutaneous drug delivery” [J. Supercrit. Fluids 178 (2021) 105379]

2022 ◽  
Vol 179 ◽  
pp. 105416
Author(s):  
Márta Kubovics ◽  
Sara Rojas ◽  
Ana M. López-Periago ◽  
Julio Fraile ◽  
Patricia Horcajada ◽  
...  
Polymers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1347
Author(s):  
Arbanah Muhammad ◽  
Dabin Lee ◽  
Yonghun Shin ◽  
Juhyun Park

Porous polysaccharides have recently attracted attention due to their porosity, abundance, and excellent properties such as sustainability and biocompatibility, thereby resulting in their numerous applications. Recent years have seen a rise in the number of studies on the utilization of polysaccharides such as cellulose, chitosan, chitin, and starch as aerogels due to their unique performance for the fabrication of porous structures. The present review explores recent progress in porous polysaccharides, particularly cellulose and chitosan, including their synthesis, application, and future outlook. Since the synthetic process is an important aspect of aerogel formation, particularly during the drying step, the process is reviewed in some detail, and a comparison is drawn between the supercritical CO2 and freeze drying processes in order to understand the aerogel formation of porous polysaccharides. Finally, the current applications of polysaccharide aerogels in drug delivery, wastewater, wound dressing, and air filtration are explored, and the limitations and outlook of the porous aerogels are discussed with respect to their future commercialization.


2004 ◽  
Vol 99 (2) ◽  
pp. 231-240 ◽  
Author(s):  
Carlos Elvira ◽  
Alejandra Fanovich ◽  
Mar Fernández ◽  
Julio Fraile ◽  
Julio San Román ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4772
Author(s):  
Liane Meneses ◽  
Rita Craveiro ◽  
Ana Rita Jesus ◽  
Maria A. M. Reis ◽  
Filomena Freitas ◽  
...  

In this work, we propose the utilization of scCO2 to impregnate ibuprofen into the mcl-PHA matrix produced by Pseudomonas chlororaphis subs. aurantiaca (DSM 19603). The biopolymer has adhesive properties, is biocompatible and has a melting temperature of 45 °C. Several conditions, namely, pressure (15 and 20 MPa) and impregnation time (30 min, 1 h and 3 h) were tested. The highest ibuprofen content (90.8 ± 6.5 mg of ibuprofen/gPHA) was obtained at 20 MPa and 40 °C, for 1 h, with an impregnation rate of 89 mg/(g·h). The processed mcl-PHA samples suffered a plasticization, as shown by the decrease of 6.5 °C in the Tg, at 20 MPa. The polymer’s crystallinity was also affected concomitantly with the matrices’ ibuprofen content. For all the impregnation conditions tested the release of ibuprofen from the biopolymer followed a type II release profile. This study has demonstrated that the mcl-PHA produced by P. chlororaphis has a great potential for the development of novel topical drug delivery systems.


2008 ◽  
Vol 43 (6) ◽  
pp. 1939-1947 ◽  
Author(s):  
Ana M. López-Periago ◽  
Arlette Vega ◽  
Pascale Subra ◽  
Anna Argemí ◽  
Javier Saurina ◽  
...  

2008 ◽  
Vol 60 (3) ◽  
pp. 373-387 ◽  
Author(s):  
Owen R. Davies ◽  
Andrew L. Lewis ◽  
Martin J. Whitaker ◽  
Hongyun Tai ◽  
Kevin M. Shakesheff ◽  
...  

2015 ◽  
Vol 101 ◽  
pp. 117-123 ◽  
Author(s):  
Ai-Zheng Chen ◽  
Na Tang ◽  
Shi-Bin Wang ◽  
Yong-Qiang Kang ◽  
Hu-Fan Song

Author(s):  
Márta Kubovics ◽  
Sara Rojas ◽  
Ana M. López ◽  
Julio Fraile ◽  
Patricia Horcajada ◽  
...  

2004 ◽  
Vol 845 ◽  
Author(s):  
Alexandru D. Asandei ◽  
Can Erkey ◽  
Diane J. Burgess ◽  
Carl Saquing ◽  
Gobinda Saha ◽  
...  

ABSTRACTThe synthesis of poly(lactic-co-glycolic acid) (PLGA) by the ring opening copolymerization of D, L-lactide and glycolide was performed at 110 °C to 130 °C using Sn(Oct)2 as catalyst, 1, 10-decanediol as initiator in a supercritical sc-CO2 expanded medium at pressures of up to 3, 500 psi. Due to the limited monomer solubility in sc-CO2 at low temperatures (70 °C), only Mn = 2, 500 is typically obtained. However, molecular weight increases with both temperature and sc-CO2 pressure. Thus, Mn = 13, 000 (PDI = 1.28) was obtained at 110 °C - 130 °C even in the absence of fluorinated surfactants. Biodegradable drug delivery nanocomposites based on dexamethasone and poly(lactic acid) (PLA) and poly(lactide-co-glycolide) (PLGA) were prepared by the rapid expansion of the corresponding supercritical CHClF2 solutions (110 °C, 200-300 bar) in air (RESS) and in toluene (RESOLV). The RESS process leads to a broad particle size distribution (100-500 nm) while the RESOLV generates a narrower distribution centered around 100 nm and is accompanied by the formation of a few large particles, most likely due to aggregation.


Sign in / Sign up

Export Citation Format

Share Document