Electron-beam modification of DLC coatings for biomedical applications

2017 ◽  
Vol 311 ◽  
pp. 248-256 ◽  
Author(s):  
G. Gotzmann ◽  
J. Beckmann ◽  
C. Wetzel ◽  
B. Scholz ◽  
U. Herrmann ◽  
...  
Keyword(s):  
Electron Beam ◽  
Biomedical Applications ◽  
Dlc Coatings

scholarly journals Long-term stable surface modification of DLC coatings

2017 ◽  
Vol 3 (2) ◽  
pp. 351-354 ◽  
Author(s):  
Gaby Gotzmann
Keyword(s):  
Surface Modification ◽  
Electron Beam ◽  
Biomedical Applications ◽  
Low Energy ◽  
Energy Electron ◽  
Electron Beam Treatment ◽  
Dlc Coatings ◽  
Low Energy Electron ◽  
The Stability

AbstractThe use of coatings based on diamond like carbon (DLC) for medical applications was established during the last years. Main advantages of these coatings are its high hardness, good wear and friction behavior and its biocompatibility. Using low-energy electron-beam treatment, we addressed the surface modification of DLC coatings. The aim was to generate new biofunctional surface characteristics that are long-term stable.Electron-beam modification resulted in significantly increased surface hydrophilicity, giving rise to the conclusion, that biological reaction on these surfaces will also be influenced by the modification. Furthermore, the stability of the surface modification was investigated. Therefore, the modified samples were stored for 8 weeks under ambient conditions. Additionally, the samples were stored in physiological saline solution at 37°C for 8 weeks. The stability of the modification was analyzed by contact angle measurement confirming no changes over the whole period of storage. In addition, the stability against standard cleaning and sterilization procedures was investigated. The durability of the modification to withstand these cleaning procedures was also proven.With these findings, the low-energy electron-beam modification seems to be a suitable tool for surface modification of DLC coatings. Thereby, the very good long-term stability is a great improvement in comparison to conventional surface modification methods like plasma treatment. In order to investigate the suitability of the modified coatings for biomedical applications, the cellular response was investigated using human fibroblasts, revealing a significantly reduced cell count on modified surfaces while maintaining their biocompatibility. By modification of the DLC surfaces, it is possible to adapt the cell adhesion on the treated surface areas. These findings demonstrate electron-beam treatment to be applicable for partial surface modification and functionalization within biomedical applications.

Additive Manufacturing for Medical and Biomedical Applications: Advances and Challenges

2014 ◽  
Vol 783-786 ◽  
pp. 1286-1291 ◽  
Author(s):  
Andrey Koptioug ◽  
Lars Erik Rännar ◽  
Mikael Bäckström ◽  
Marie Cronskär
Keyword(s):  
Electron Beam ◽  
Additive Manufacturing ◽  
Electron Beam Melting ◽  
Biomedical Applications ◽  
Rapid Development ◽  
Industrial Applications ◽  
Post Processing ◽  
New Materials ◽  
Industrial Manufacturing ◽  
Complex Shapes

Additive Manufacturing (AM) has solidly established itself not only in rapid prototyping but also in industrial manufacturing. Its success is mainly determined by a possibility of manufacturing components with extremely complex shapes with minimal material waste. Rapid development of AM technologies includes processes using unique new materials, which in some cases is very hard or impossible to process any other way. Along with traditional industrial applications AM methods are becoming quite successful in biomedical applications, in particular in implant and special tools manufacturing. Here the capacity of AM technologies in producing components with complex geometric shapes is often brought to extreme. Certain issues today are preventing the AM methods taking its deserved place in medical and biomedical applications. Present work reports on the advances in further developing of AM technology, as well as in related post-processing, necessary to address the challenges presented by biomedical applications. Particular examples used are from Electron Beam Melting (EBM), one of the methods from the AM family.

Characterization of electron beam deposited Nb2O5 coatings for biomedical applications

2020 ◽  
Vol 103 ◽  
pp. 103582 ◽  
Author(s):  
Mihaela Dinu ◽  
Laurentiu Braic ◽  
Sibu C. Padmanabhan ◽  
Michael A. Morris ◽  
Irina Titorencu ◽  
...  
Keyword(s):  
Electron Beam ◽  
Biomedical Applications

Enhancing and controlling the critical attributes of poly ( N ‐vinylcaprolactam) through electron beam irradiation for biomedical applications

2019 ◽  
Vol 137 (18) ◽  
pp. 48639
Author(s):  
Shane Halligan ◽  
Kieran Murray ◽  
Michael Hopkins ◽  
Ian Rogers ◽  
John Lyons ◽  
...  
Keyword(s):  
Electron Beam ◽  
Biomedical Applications ◽  
Electron Beam Irradiation ◽  
Beam Irradiation

scholarly journals Electron-Beam-Induced Grafting of Chitosan onto HDPE/ATZ Composites for Biomedical Applications

Polymers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 4016
Author(s):  
Maria Giulia Faga ◽  
Donatella Duraccio ◽  
Mattia Di Maro ◽  
Christelle Kowandy ◽  
Giulio Malucelli ◽  
...  
Keyword(s):  
Electron Beam ◽  
Biomedical Applications ◽  
Electrostatic Interactions ◽  
Detrimental Effect ◽  
Ftir Analysis ◽  
Biological Assays ◽  
Grafting Reaction ◽  
Surface Functionalisation ◽  
Irradiation Process ◽  
Surface Changes

The surface functionalisation of high-density polyethylene (HDPE) and HDPE/alumina-toughened zirconia (ATZ) surfaces with chitosan via electron-beam (EB) irradiation technique was exploited for preparing materials suitable for biomedical purposes. ATR–FTIR analysis and wettability measurements were employed for monitoring the surface changes after both irradiation and chitosan grafting reaction. Interestingly, the presence of ATZ loadings beyond 2 wt% influenced both the EB irradiation process and the chitosan functionalisation reaction, decreasing the oxidation of the surface and the chitosan grafting. The EB irradiation induced an increase in Young’s modulus and a decrease in the elongation at the break of all analysed systems, whereas the tensile strength was not affected in a relevant way. Biological assays indicated that electrostatic interactions between the negative charges of the surface of cell membranes and the –NH3+ sites on chitosan chains promoted cell adhesion, while some oxidised species produced during the irradiation process are thought to cause a detrimental effect on the cell viability.

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