Fast separation and analysis of reduced monoclonal antibodies with capillary zone electrophoresis coupled to mass spectrometry

Talanta ◽  
2016 ◽  
Vol 148 ◽  
pp. 529-533 ◽  
Author(s):  
Yimeng Zhao ◽  
Liangliang Sun ◽  
Michael D. Knierman ◽  
Norman J. Dovichi
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibodies ◽  
Capillary Zone Electrophoresis ◽  
Fast Separation ◽  
Zone Electrophoresis ◽  
Capillary Zone

Comprehensive analysis of host cell impurities in monoclonal antibodies with improved sensitivity by capillary zone electrophoresis mass spectrometry

2016 ◽  
Vol 38 (3-4) ◽  
pp. 401-407 ◽  
Author(s):  
Zhenbin Zhang ◽  
Thomas Albanetti ◽  
Travis Linkous ◽  
Christopher J. Larkin ◽  
Ronald Schoner ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibodies ◽  
Host Cell ◽  
Capillary Zone Electrophoresis ◽  
Comprehensive Analysis ◽  
Zone Electrophoresis ◽  
Capillary Zone

scholarly journals Monoclonal antibodies biosimilarity assessment using transient isotachophoresis capillary zone electrophoresis-tandem mass spectrometry

mAbs ◽  
2014 ◽  
Vol 6 (6) ◽  
pp. 1464-1473 ◽  
Author(s):  
Rabah Gahoual ◽  
Michaël Biacchi ◽  
Johana Chicher ◽  
Lauriane Kuhn ◽  
Philippe Hammann ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibodies ◽  
Tandem Mass Spectrometry ◽  
Capillary Zone Electrophoresis ◽  
Tandem Mass ◽  
Zone Electrophoresis ◽  
Capillary Zone

scholarly journals Capillary zone electrophoresis tandem mass spectrometry detects low concentration host cell impurities in monoclonal antibodies

2016 ◽  
Vol 37 (4) ◽  
pp. 616-622 ◽  
Author(s):  
Guijie Zhu ◽  
Liangliang Sun ◽  
Jennifer Heidbrink-Thompson ◽  
Srilatha Kuntumalla ◽  
Hung-yu Lin ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibodies ◽  
Tandem Mass Spectrometry ◽  
Host Cell ◽  
Capillary Zone Electrophoresis ◽  
Tandem Mass ◽  
Low Concentration ◽  
Zone Electrophoresis ◽  
Capillary Zone

Identification of human chorionic gonadotropin hormone in illegally distributed products by MALDI-TOF mass spectrometry and double-injection capillary zone electrophoresis

2016 ◽  
Vol 8 (21) ◽  
pp. 4188-4196 ◽  
Author(s):  
Andranik Durgaryan ◽  
Torgny Rundlöf ◽  
Martin Lavén ◽  
Ahmad Amini
Keyword(s):  
Mass Spectrometry ◽  
Capillary Zone Electrophoresis ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Double Injection ◽  
Maldi Tof ◽  
Zone Electrophoresis ◽  
Capillary Zone ◽  
Human Chorionic Gonadotropin Hormone ◽  
Tof Ms

MALDI-TOF-MS and double injection capillary zone electrophoresis (DICZE) were used for the identification of human chorionic gonadotropin (hCG) in illegally distributed products.

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