Women's values and preferences and health state valuations for thromboprophylaxis during pregnancy: A cross-sectional interview study

Abstract Purpose Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that affects up to 1% of the population in Europe. The EQ-5D is the most commonly used generic instrument for measuring health-related quality of life among HS patients. This study aims to compare the measurement properties of the two adult versions of EQ-5D (EQ-5D-3L and EQ-5D-5L) in patients with HS. Methods We recruited 200 consecutive patients with HS (mean age 37 years, 38% severe or very severe HS) to participate in a multicentre cross-sectional survey. Patients completed the EQ-5D-3L, EQ-5D-5L, Dermatology Life Quality Index (DLQI) and Skindex-16 questionnaires. Results More than twice as many different health state profiles occurred in the EQ-5D-5L compared to the EQ-5D-3L (101 vs. 43). A significant reduction in ceiling effect was found for the mobility, self-care and usual activities dimensions. A good agreement was established between the EQ-5D-3L and EQ-5D-5L with an intraclass correlation coefficient of 0.872 (95% CI 0.830–0.903; p < 0.001) that was confirmed by a Bland-Altman plot. EQ-5D-5L improved both the absolute and relative informativity in all dimensions except for anxiety/depression. EQ-5D-3L and EQ-5D-5L demonstrated similar convergent validity with DLQI and Skindex-16. EQ-5D-5L was able to better discriminate between known groups of patients based on the number of comorbidities and disease severity (HS-Physician's Global Assessment). Conclusion In patients with HS, the EQ-5D-5L outperformed the EQ-5D-3L in feasibility, ceiling effects, informativity and known-groups validity for many important clinical characteristics. We recommend using the EQ-5D-5L in HS patients across various settings, including clinical care, research and economic evaluations.

Download Full-text

Establishing health state valuations for disease specific states: an example from heart disease

Health Economics ◽

10.1002/(sici)1099-1050(200003)9:2<149::aid-hec501>3.0.co;2-n ◽

2000 ◽

Vol 9 (2) ◽

pp. 149-158 ◽

Cited By ~ 30

Author(s):

J. Kirsch ◽

A. McGuire

Keyword(s):

Heart Disease ◽

Health State ◽

Health State Valuations ◽

Disease Specific

Download Full-text

Time preference, duration and health state valuations

Health Economics ◽

10.1002/hec.4730040405 ◽

1995 ◽

Vol 4 (4) ◽

pp. 289-299 ◽

Cited By ~ 79

Author(s):

Paul Dolan ◽

Claire Gudex

Keyword(s):

Time Preference ◽

Health State ◽

Health State Valuations

Download Full-text

Painful diabetic neuropathy: a cross-sectional survey of health state impairment and treatment patterns

Journal of Diabetes and its Complications ◽

10.1016/j.jdiacomp.2005.09.007 ◽

2006 ◽

Vol 20 (1) ◽

pp. 26-33 ◽

Cited By ~ 119

Author(s):

Thomas Tölle ◽

Xiao Xu ◽

Alesia B. Sadosky

Keyword(s):

Diabetic Neuropathy ◽

Treatment Patterns ◽

Health State ◽

Painful Diabetic Neuropathy ◽

Cross Sectional Survey ◽

Cross Sectional

Download Full-text

Health state of the citizens of Nothern Kosovska Mitrovica

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh1012746m ◽

2010 ◽

Vol 138 (11-12) ◽

pp. 746-751

Author(s):

Momcilo Mirkovic ◽

Snezana Simic ◽

Jelena Marinkovic ◽

Sladjana Djuric

Keyword(s):

Health Survey ◽

Health Assessment ◽

Population Level ◽

Cross Sectional Study ◽

Health Condition ◽

Health State ◽

Cross Sectional ◽

Significance Level ◽

Self Rated Health ◽

Significant Difference

Introduction. For health assessment, beside the data of routine health statistics, it is necessary to include and data obtained by a health survey of the citizens. Objective. The aim of this study was to establish how northern Kosovska Mitrovica adults assess their health and which diseases are most common among the population, as well as to investigate differences in relation to demographic and socioeconomic characteristics, the characteristics of social interaction and health behavior and habits. Methods. The research was conducted as a cross-sectional study conducted on the representative sample of adult citizens in northern Kosovska Mitrovica in 2006. Two hundred-eighteen respondents were included in the survey. In the research we used a questionnaire identical to the Health Survey conducted in Serbia in 2006. The significance of differences in responses about self-rated health and chronic diseases in relation to the characteristics of respondents? responses were determined by X2-test with the significance level of 0.05. Results. Over half of the respondents (54.7%) assessed their health condition as good or very good. There was a significant difference in self-rated health in relation to the respondents? age (?2=202.036; p=0.000), education (?2=72.412; p=0.000), social support (?2=12.416; p=0.015), smoking (?2=11.675; p=0.020) and physical activity (?2=61.842; p=0.000). The leading health problems among the respondents were high blood pressure, rheumatologic diseases of joints, ulcer of the duodenal or gastric ulcer, gall bladder disease and high blood fat. Conclusion. Adult residents of northern Kosovska Mitrovica assessed their health as better than the residents of Serbia without Kosovo and Metohia. The diseases in which stress plays the major role among etiological factors are in the leading position. The obtained data on the population level of specific areas represent the basis in the planning of health education and health promotion activities.

Download Full-text

THE IMPACT OF MEDICATION ADHERENCE ON HEALTH-RELATED QUALITY OF LIFE OF DIABETIC PATIENTS IN THE KINGDOM OF SAUDI ARABIA: FINDINGS FROM A CROSS-SECTIONAL STUDY

Periódico Tchê Química ◽

10.52571/ptq.v17.n34.2020.891_p34_pgs_867_873.pdf ◽

2020 ◽

Vol 17 (34) ◽

pp. 867-873

Author(s):

Dhfer ALSHAYBAN ◽

Royes JOSEPH

Keyword(s):

Quality Of Life ◽

Medication Adherence ◽

Cross Sectional Study ◽

P Value ◽

Diabetic Patients ◽

Health State ◽

Cross Sectional ◽

Related Quality ◽

The Impact

Diabetes is a common chronic disease that is considered as one of the fastest-growing health problems in the world. Adherence to medications could be an important factor in reducing these complications and improving the quality of life. The purpose of this research was to assess the impact of treatment adherence on health-related quality of life in patients with type 2 diabetes. A multicenter cross-sectional study was carried out among 368 diabetes patients. General Medication Adherence Scale was used to assess the adherence level and EuroQol-5D to assess the quality of life. The results show that 19%, 21%, and 23% of patients had maintained low medication adherence due to patient’s intentional or unintentional behavior due to additional diseases or pills burden and due to financial constraints, respectively. Overall, 43% (n=162) participants had maintained high medication adherence, and 37% (n=138) had maintained low medication adherence to antidiabetic drugs. Nearly one-third (31%) of patients with high overall adherence had perfect health state in comparison with 4% among patients with low adherence. Further, the lower proportion (21%) of patients with high overall adherence had perfect health state in comparison with that among patients with low adherence (34%). In addition to the overall adherence, the association was statistically significant for the domains related to non-adherence due to the patient’s intentional or unintentional behavior (p-value 0.001) and non-adherence due to additional diseases or pills burden (p-value 0.001) after taking into account of socio-demographic and clinical characteristics. In conclusion, the findings suggest that the policymakers should establish an intervention to improve adherence to diabetic treatment, and thus improve the quality of life for the type 2 diabetic patients.

Download Full-text

The Characteristics and Motivations of Online Health Information Seekers: Cross-Sectional Survey and Qualitative Interview Study

Journal of Medical Internet Research ◽

10.2196/jmir.1600 ◽

2011 ◽

Vol 13 (1) ◽

pp. e20 ◽

Cited By ~ 243

Author(s):

John Powell ◽

Nadia Inglis ◽

Jennifer Ronnie ◽

Shirley Large

Keyword(s):

Health Information ◽

Qualitative Interview ◽

Interview Study ◽

Online Health Information ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Qualitative Interview Study

Download Full-text

Cross-sectional associations between inflammation, sickness behaviour, health anxiety and self-rated health in a Swedish primary care population

European Journal of Inflammation ◽

10.1177/2058739219844357 ◽

2019 ◽

Vol 17 ◽

pp. 205873921984435 ◽

Cited By ~ 2

Author(s):

Karin Lodin ◽

Mats Lekander ◽

Predrag Petrovic ◽

Gustav Nilsonne ◽

Erik Hedman-Lagerlöf ◽

...

Keyword(s):

Primary Care ◽

Interleukin 6 ◽

Health Anxiety ◽

Health State ◽

Sickness Behaviour ◽

Cross Sectional ◽

Primary Care Population ◽

Self Rated Health ◽

Primary Care Patients ◽

Low Levels

This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour ( ρ = 0.28, P < 0.001; ρ = 0.42, P = 0.003) and high health anxiety ( ρ = 0.31, P < 0.001; ρ = –0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men ( ρ = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women ( ρ = –0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety ( ρ = –0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.

Download Full-text

Treatment of venous thromboembolism with vitamin K antagonists: patients’ health state valuations and treatment preferences

Thrombosis and Haemostasis ◽

10.1160/th04-02-0075 ◽

2004 ◽

Vol 92 (12) ◽

pp. 1336-1341 ◽

Cited By ~ 40

Author(s):

Patrick Bossuyt ◽

Peep Stalmeier ◽

Mirjam Sprangers ◽

Carlo van Dongen ◽

Saskia Middeldorp ◽

...

Keyword(s):

Venous Thromboembolism ◽

Vitamin K ◽

Vitamin K Antagonists ◽

Patient Characteristics ◽

Haemorrhagic Stroke ◽

Treatment Preferences ◽

Health State ◽

Health States ◽

Health State Valuations ◽

Cessation Of Treatment

SummaryDetermining the optimal duration of vitamin K antagonist (VKA) therapy for patients with venous thromboembolism (VTE) requires a weighting of the benefits and risks of treatment. The objectives of our study were to investigate patient variability in health state valuations associated with VKA therapy and treatment preferences, and to investigate the extent to which valuations and treatment preferences are associated with prior experience with these health states and other patient characteristics. Valuations of outcomes after VTE scaled from 0 (tantamount to death) to 1 (tantamount to perfect health) were elicited from 53 patients who had experienced VTE, 23 patients who had experienced major bleeding during treatment, and 48 patients with the post-thrombotic syndrome. In addition, patients’ treatment preferences were evaluated using treatment trade-off questions. Median health state valuations ranged from 0.33 for ‘non-fatal haemorrhagic stroke’ to 0.96 for ‘no VKA treatment’. Variability between patients was substantial. Patients’ treatment preferences also varied: 25% of patients chose cessation of treatment, regardless of the probability of recurrent VTE presented, whereas 23% of patients were never willing to choose cessation of treatment. Differences in valuations and treatment preferences were not associated with type of event experienced. Due to the substantial and unpredictable variability in valuations and treatment preferences, recommendations regarding treatment duration should be tailored to patients’ specific values and concerns.

Download Full-text