scholarly journals THE IMPACT OF MEDICATION ADHERENCE ON HEALTH-RELATED QUALITY OF LIFE OF DIABETIC PATIENTS IN THE KINGDOM OF SAUDI ARABIA: FINDINGS FROM A CROSS-SECTIONAL STUDY

2020 ◽  
Vol 17 (34) ◽  
pp. 867-873
Author(s):  
Dhfer ALSHAYBAN ◽  
Royes JOSEPH

Diabetes is a common chronic disease that is considered as one of the fastest-growing health problems in the world. Adherence to medications could be an important factor in reducing these complications and improving the quality of life. The purpose of this research was to assess the impact of treatment adherence on health-related quality of life in patients with type 2 diabetes. A multicenter cross-sectional study was carried out among 368 diabetes patients. General Medication Adherence Scale was used to assess the adherence level and EuroQol-5D to assess the quality of life. The results show that 19%, 21%, and 23% of patients had maintained low medication adherence due to patient’s intentional or unintentional behavior due to additional diseases or pills burden and due to financial constraints, respectively. Overall, 43% (n=162) participants had maintained high medication adherence, and 37% (n=138) had maintained low medication adherence to antidiabetic drugs. Nearly one-third (31%) of patients with high overall adherence had perfect health state in comparison with 4% among patients with low adherence. Further, the lower proportion (21%) of patients with high overall adherence had perfect health state in comparison with that among patients with low adherence (34%). In addition to the overall adherence, the association was statistically significant for the domains related to non-adherence due to the patient’s intentional or unintentional behavior (p-value 0.001) and non-adherence due to additional diseases or pills burden (p-value 0.001) after taking into account of socio-demographic and clinical characteristics. In conclusion, the findings suggest that the policymakers should establish an intervention to improve adherence to diabetic treatment, and thus improve the quality of life for the type 2 diabetic patients.

2018 ◽  
Vol 14 (1) ◽  
pp. 264-269 ◽  
Author(s):  
Patricia Ciminelli ◽  
Sergio Machado ◽  
Manoela Palmeira ◽  
Mauro Giovanni Carta ◽  
Sarah Cristina Beirith ◽  
...  

Background: Emotional stress is frequently associated with otologic symptoms as tinnitus and dizziness. Stress can contribute to the beginning or worsening of tinnitus. Objective: The objective of the study is to evaluate the presence of stress symptoms in patients with chronic, subjective tinnitus, and correlate its presence to annoyance associated with tinnitus. Methods: This is a cross-sectional study. One hundred and eighty patients with chronic, subjective tinnitus were included. Patients answered the Tinnitus Handicap Inventory (THI) to evaluate the impact of tinnitus in the quality of life and answered the Lipp's inventory symptoms of stress for adults (ISSL). The data obtained was organized using Excel® 2010, mean values, linear regression and p-value were calculated. Results: Of the 180 patients included in the study, 117 (65%) had stress symptoms, 52 of the 117 (44%) were in the resistance phase and 23 of the 117 (20%) in the exhaustion phase, the remaining was in the alert phase. There was a clear progressive increase in stress as THI raised, with more impact of tinnitus in quality of life. Conclusion: The presence of stress symptoms, measured by ISSL was observed in most of our patients with chronic subjective tinnitus, specially in the resistance and exhaustion phases and it is directly associated with tinnitus annoyance.


2021 ◽  
Vol 71 (2) ◽  
pp. 629-33
Author(s):  
Nadia Ramzan ◽  
Samreen Misbah ◽  
Shehla Baqai ◽  
Syed Fawad Mashhadi ◽  
Imtenan Sharif ◽  
...  

Objective: The study was conducted to assess the maternal health related quality of life and its affecting factors in postpartum period. Study Design: Analytical cross-sectional study. Place and Duration of Study: The study was done in a tertiary care hospital, Rawalpindi, from Mar to Jun 2019.Methodology: By using non-probability purposive sampling technique, sample of 268 women in post-partum period were interviewed. A validated short form-36 (SF-36) Questionnaire was administered to women aged 15-49 years, who had spontaneous vaginal delivery or cesarean section, and were within six weeks up to six months of postpartum period. Data was analyzed by using SPSS-22. A p-value of ≤0.05 was taken as significant. Results: Highest median scores were reported in physical functioning 75 (55, 90) and social functioning 75 (75, 62). Lowest median scores were reported in energy fatigue 37 (31, 50) body pain 45 (22, 62) and general health 45 (30, 60). Health-related quality of life scores showed significant difference (p-value <0.05) among subgroups of time since delivery, mode of delivery, education of women, husband’s education and antenatal visits. Conclusion: The study showed that health related quality of life score of postpartum women was moderately affected; where in physical and social functioning domains strongly contributes in better quality of life. Energy/fatigue, body pain and general health are the weakest domains adversely affecting quality of life. Women in subacute postpartum phase, with cesarean section, lower educational status and less than 04 antenatal visits are associated with poorer HRQOL.


2011 ◽  
Vol 11 (3) ◽  
pp. 297-303 ◽  
Author(s):  
Dimitrios Tziallas ◽  
Catherine Kastanioti ◽  
Michael S Kostapanos ◽  
Petros Skapinakis ◽  
Moses S Elisaf ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Maher R. Khdour ◽  
Heba B. Awadallah ◽  
Dua’a H. Al-Hamed

Objectives. This study had the goal of evaluating the role of treatment satisfaction among diabetic patients in the context of health-related quality of life (QoL) and medication adherence. Methods. This study, which utilized a cross-sectional design, was conducted at the Primary Healthcare Unit in the Ministry of Health in Ramallah between Feb. and May 2019. Medication adherence was evaluated with the 4-item Morisky Green-Levine (MGL) questionnaire, treatment satisfaction using the Treatment Satisfaction Questionnaire for Medication version 1.4 (TSQM 1.4), and health-related quality of life with the European Quality of Life scale (EQ-5D-3L). Results. Study participants consisted of 380 diabetic patients, of which 220 (57.9%) had high adherence to their medications and 160 (42.1%) had low adherence. Based on the classification of patient responses among the EQ-5D domains, pain/discomfort was the most influenced dimension, with 173 patients (36.1%) reporting problems, (36.1%). Also prominent were anxiety and depression (128 patients, 33.7%) and Mobility (115 patients, 30.3%). A significant relation was observed between QoL and treatment satisfaction (73.8 vs. 69.8; P=0.016). Treatment satisfaction also had a significant association with the anxiety domain (39.4 vs. 28.7; P=0.031). Conclusion. Participants expressed moderate satisfaction with their treatments; more satisfied patients showed greater medication adherence and had better QoL. Anxiety has been shown to be associated with reduced medication adherence and lower QoL.


2021 ◽  
Vol 26 (suppl 3) ◽  
pp. 5233-5240
Author(s):  
Juliana Andrade de Lacerda ◽  
Técia Mendes Daltro Borges ◽  
Marcelo de Castro Meneguim ◽  
Mario Vedovello Filho ◽  
Milton Santamaria Júnior ◽  
...  

Abstract The aim of this study was to evaluate the impact of malocclusion severity on the oral health-related quality of life (OHRQoL) of non-white adolescents. A cross-sectional study was conducted with 585 non-white Brazilian adolescents (12-15 years). The Dental Aesthetic Index (DAI) was used for the clinical assessment of malocclusion and Oral Health Impact Profile (OHIP-14) on OHRQoL. Deep bite and transverse occlusal relationships were assessed in association with the DAI. The adolescents with DAI 3 and 4 were distributed into 4 groups: G1 - individuals without transverse occlusal relationships or deep bite; G2 - individuals with only posterior crossbite; G3 - individuals with only deep bite; and G4 - individuals with Brodie bite. The backward stepwise procedure was used to select variables on each level, eliminating variables with a p≤0.20. From the logistic regression analyses, the adjusted odds ratios were estimated with the respective 95% confidence intervals. The adolescents with severe malocclusion divided into the G2, G3 and G4 showed p-value of 0.0501, 0.1475, and 0.5407, respectively, but did not remain in the final model. Malocclusion severity had no impact on the OHRQoL of non-white adolescents.


2019 ◽  
Author(s):  
Bikila Regassa Feyisa ◽  
Mekdes Tigistu Yilma ◽  
Belachew Etana Tolessa

AbstractObjectiveTo assess health related quality of life (HRQoL) and its predictors among diabetic patients on follow up at Nekemte Specialized Hospital (NSH) in Western Ethiopia.Design, setting and participantsThis facility based cross sectional study was conducted among 224 diabetic patients on follow up at one of the public hospitals in western Ethiopia.Main outcome measuredHRQoL was measured by using the Medical Outcome Study 36-item Short Form Health Survey from 15th April to 5th June. Structured questionnaire was used for data the collection from participants selected by systematic random sampling. Multiple linear regression was used for final model.ResultA total of 215 diabetic patients were involved in the study with the response rate of 96%. The mean score of the overall HRQoL of the study participants was found to be 50.30 ± 18.08 with highest mean score in physical functioning and lowest mean score in general health domain. Age, education status, history of smoking, feeling of stigmatized and Body mass index (BMI) were inversely associated while being male, being married, absence of co morbidity and absence of chronic complications related to diabetes mellitus were found to be positively associated with overall HRQoL.ConclusionThe overall HRQoL of diabetic patients on follow up at the study area was found to be moderate. General health, mental health, bodily pain and vitality were the most affected domains. Both the mental and physical components need to be considered when caring the diabetic patients on follow up beyond provision of treatment.Strength and limitations of this studyThe study was the first of its kind in assessing the predictors of health-related quality of life (HRQoL) among both diabetes mellitus type I and type II in Ethiopia.The tools used was validated across different culturesEight domains of HRQoL and two component summary scores were used to make the measurement more specific.The cross sectional nature of the study design made the result of the study difficult to identify either the cause or the effect comes first.


Author(s):  
Habib Jalilian ◽  
Ali Imani ◽  
Habibeh Mir ◽  
Elnaz Javanshir ◽  
Mehdi Mamene ◽  
...  

Background: A heart attack is one of the most common cardiovascular diseases, affecting different dimensions of the patients’ quality of life due to the disease’s disabling and limiting nature. Therefore, this study aimed to examine the impact of myocardial infarction on patients’ quality of life referring to the Shahid Madani Medical & Training Hospital, in East Azerbaijan Province in 2017, in Iran. Methods: This was a cross-sectional study. A total of 220 patients with a heart attack were selected in this study. Sampling was conducted using the systematic random method. Data were collected using the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Descriptive statistics (frequency, mean) and statistical analyses (Mann-Whitney test, Spearman correlation, and Generalized Linear Models Regression) were performed at a significance level of P-value < 0.05 using SPSS22. Results: In this study, the mean score of the total effect of a heart attack on the patients’ quality of life was 30.09 ± 17.73. The mean score of the effect of a heart attack on the patient’s quality of life in the physical, emotional, and general subscales was 34.85 ± 24.24, 26.63 ± 27.73, and 27.51 ± 17.83, respectively. There was a statistically significant association between education status (P-value = 0.006), income status (P- value = 0.000), and the mean score of the effect of a heart attack on the patient’s quality of life; also a positive and significant correlation was found between age (CC = 0.135, P-value = 0.046), the number of hospitalization (CC = 0.187, P-value = 0.006) and the mean score of the effect of a heart attack on the patient’s quality of life. Conclusion: A heart attack has a considerable impact on the patients’ quality of life, particularly on the physical dimension. Hence, health professionals should pay more attention to these vulnerable groups and offer rehabilitation services suitable to these groups to reduce the impact of the disease.


2021 ◽  
Author(s):  
Ruwaydah Ahmed Meelad ◽  
Intan Juliana Abd Hamid ◽  
Zarina Thasneem Zainudeen ◽  
Ilie Fadzilah Hashim ◽  
Muhd Nur Akmal Azizuddin ◽  
...  

Abstract Purpose: Primary immunodeficiency disease (PID) affects various aspects of a patient’s life. However, the health-related quality of life (HRQOL) of PID patients in Malaysia patients is poorly described. This study aimed to determine the quality of life of Malaysian PID patients and parents. Method: This cross-sectional study was performed from August 2020 to November 2020. Patients with PID and their families were invited to answer the PedsQL Malay version (4.0) questionnaire, the tool used to assess the HRQOL. A total of 41 families and 33 patients with PID answered the questionnaire. A comparison was performed with the previously published value of healthy Malaysian children. Result: Parent of respondents recorded a lower mean of total score than the parents of normal healthy children (67.26±16.73 vs. 79.51±11.90, p-value = 0.001, respectively). PID patients reported lower mean total score to normal healthy children (73.68 ± 16.38 vs. 79.51 ± 11.90, p-value = 0.04), including psychosocial domain (71.67±16.82 vs. 77.58±12.63, p-value = 0.05), and school functioning, (63.94±20.87 vs. 80.00 ± 14.40, p-value = 0.007). No significant difference of reported HRQOL when comparing between subgroup of PID on immunoglobulin replacement therapy and those without immunoglobulin replacement (56.96±23.58 vs. 65.83±23.82, p-value 0.28). Socioeconomic status was found to be predictive of the lower total score of PedsQL in both parent and children reports. Conclusion: Parents and children with PID, especially those from middle socioeconomic status, have lower HRQOL and school function impairment than healthy children.


2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Norhayati A. H ◽  
Nur Diyana K.A ◽  
M. S. Muhaimin ◽  
Ezmas Mahno ◽  
A W Ahmad ◽  
...  

Introduction: Peripheral Occlusive Arterial Disease (POAD) is an important cardiovascular morbidity especially among diabetics. The goal of the treatment is to improve patients’ quality of life (QoL) starting by quantifying the disease burden in our population especially among high risk group such as diabetics. Materials and Methods: This cross-sectional study aims to provide a data on the prevalence of POAD among diabetic population in a primary health care in Kuantan and its’ effects on the patient’s QoL. Additionally, we examined for any other stipulated associated factors that may have contributed towards the development of POAD. We applied a universal sampling for the purpose of patient selection. POAD is universally defined as ankle-brachial index (ABI) of lower than 0.9. Individuals were assessed on validated Malay version of WHOQOL BREF to assess their QoL parameters. P value of <0.05 considered as statistically significant. This study was registered with the National Medical Research Register (NMRR registration no. 17-1375-35710). Results: The prevalence of PAD among diabetic patients in Klinik Kesihatan (Local General Practitioner) Jaya Gading, Kuantan was found to be 20%. We found a significant relationship between lower levels of education (p = 0.016), older age group (p = 0.02) and lower economic class (p = 0.03) with the presence of POAD among diabetics. The presence of POAD has a significant adverse effect on QoL evidenced by lower Physical Domain (p=0.001), Psychological Domain (p=0.066), Social Domain (p=0.005), and Environmental Domain (p=0.027) scores using validated WHOQOL BREF questionnaires. Conclusion: The significant prevalence of POAD among diabetics prompts a greater urgency for early detection to prevent the development of its’ associated morbidity and deterioration of their QoL.


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