HepaRG cell line as an in vitro model for screening drug–drug interactions mediated by metabolic induction: Amiodarone used as a model substance

2014 ◽  
Vol 28 (8) ◽  
pp. 1531-1535 ◽  
Author(s):  
Ana Ferreira ◽  
Márcio Rodrigues ◽  
Samuel Silvestre ◽  
Amílcar Falcão ◽  
Gilberto Alves
Keyword(s):  
Drug Interactions ◽  
Cell Line ◽  
In Vitro Model ◽  
Heparg Cell ◽  
Heparg Cell Line ◽  
Model Substance ◽  
Vitro Model ◽  
Metabolic Induction

The HepaRG cell line, a superior in vitro model to L-02, HepG2 and hiHeps cell lines for assessing drug-induced liver injury

2016 ◽  
Vol 32 (1) ◽  
pp. 37-59 ◽  
Author(s):  
Yu Wu ◽  
Xing-chao Geng ◽  
Ju-feng Wang ◽  
Yu-fa Miao ◽  
Yan-li Lu ◽  
...  
Keyword(s):  
Liver Injury ◽  
Cell Line ◽  
Cell Lines ◽  
In Vitro Model ◽  
Drug Induced ◽  
Heparg Cell ◽  
Drug Induced Liver Injury ◽  
Heparg Cell Line ◽  
Vitro Model

The Human Leukemic HL-60 Cell Line: An in Vitro Model for Cell Death Endpoint Identification

1996 ◽  
Vol 24 (4) ◽  
pp. 581-587
Author(s):  
Cristiana Zanetti ◽  
Arrnalaura Stammati ◽  
Orazio Sapora ◽  
Flavia Zucco
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
In Vitro Model ◽  
Leukemia Cell ◽  
Promyelocytic Leukemia ◽  
Leukemia Cell Line ◽  
Cell Type ◽  
Vitro Model ◽  
Promyelocytic Leukemia Cell Line

The aim of this study was to investigate the endpoints related to cell death, either necrosis or apoptosis, induced by four chemicals in the promyelocytic leukemia cell line, HL-60. Cell morphology, DNA fragmentation, cytofluorimetric analysis and oxygen consumption were used to classify the type of cell death observed. In our analysis, we found that not all the selected parameters reproduced the differences observed in the cell death caused by the four chemicals tested. As cell death is a very complex phenomenon, several factors should be taken into account (cell type, exposure time and chemical concentration), if chemicals are to be classified according to differences in the mechanisms more directly involved in cell death.

scholarly journals Approximation of immune response abilities in salmonid gills using the RTgill-W1 cell line as an in vitro model

2016 ◽  
Vol 53 ◽  
pp. 74
Author(s):  
Claudio Alvarez ◽  
Paula Santana ◽  
Francisco Donoso ◽  
Felipe Ramírez ◽  
Jimena Cortés ◽  
...  
Keyword(s):  
Immune Response ◽  
Cell Line ◽  
In Vitro Model ◽  
Vitro Model

The murine enterocyte cell line Mode-K is a novel and reliable in vitro model for studies on gluten toxicity

2020 ◽  
Vol 140 ◽  
pp. 111331 ◽  
Author(s):  
Diomira Luongo ◽  
Lucia Treppiccione ◽  
Francesco Maurano ◽  
Mauro Rossi ◽  
Paolo Bergamo
Keyword(s):  
Cell Line ◽  
In Vitro Model ◽  
Vitro Model

scholarly journals Optimization of an oral mucosa in vitro model based on cell line TR146

2020 ◽  
Vol 8 (2) ◽  
pp. 1748459 ◽  
Author(s):  
Grace C. Lin ◽  
Tamara Leitgeb ◽  
Alexandra Vladetic ◽  
Heinz-Peter Friedl ◽  
Nadine Rhodes ◽  
...  
Keyword(s):  
Cell Line ◽  
Oral Mucosa ◽  
In Vitro Model ◽  
Model Based ◽  
Vitro Model

In vitro model of angiogenesis using a human endothelium-derived permanent cell line: Contributions of induced gene expression, G-proteins, and integrins

1992 ◽  
Vol 153 (3) ◽  
pp. 437-449 ◽  
Author(s):  
Jeffrey Bauer ◽  
Michael Margolis ◽  
Clara Schreiner ◽  
Cora-Jean Edgell ◽  
Jane Azizkhan ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Line ◽  
G Proteins ◽  
In Vitro Model ◽  
Permanent Cell Line ◽  
Permanent Cell ◽  
Vitro Model ◽  
Human Endothelium
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