Lead (Pb) induced Oxidative Stress as a Mechanism to Cause Neurotoxicity in Drosophila melanogaster

Toxicology ◽  
2021 ◽  
pp. 152959
Author(s):  
Olakkaran Shilpa ◽  
Kizhakke Purayil Anupama ◽  
Anet Antony ◽  
Hunasanahally Puttaswamygowda Gurushankara
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster

Melatonin improves cognitive behavior, oxidative stress, and metabolism in tumor‐prone lethal giant larvae mutant of Drosophila melanogaster

2021 ◽  
Author(s):  
Kar‐Cheng Wong ◽  
Srivani Sankaran ◽  
Jaime J. Jayapalan ◽  
Perumal Subramanian ◽  
Puteri S. Abdul‐Rahman
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Cognitive Behavior ◽  
Lethal Giant Larvae

scholarly journals Effects of sodium fluoride and Ocimum sanctum extract on the lifespan and climbing ability of Drosophila melanogaster

2021 ◽  
Vol 82 (1) ◽  
Author(s):  
Sidra Perveen ◽  
Shalu Kumari ◽  
Himali Raj ◽  
Shahla Yasmin
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Drosophila Melanogaster ◽  
Sodium Fluoride ◽  
Ocimum Sanctum ◽  
Activity Assay ◽  
Lipid Peroxidation Assay ◽  
Climbing Ability ◽  
The Impact ◽  
Sublethal Concentrations

Abstract Background Fluoride may induce oxidative stress and apoptosis. It may also lead to neurobehavioural defects including neuromuscular damage. The present study aimed to explore the effects of sub lethal concentrations of sodium fluoride (NaF) on the lifespan and climbing ability of Drosophila melanogaster. In total, 0.6 mg/L and 0.8 mg/L of NaF were selected as sublethal concentrations of NaF for the study. Lifespan was measured and climbing activity assay was performed. Results The study showed significant decrease in lifespan of flies treated with fluoride. With increasing age, significant reduction in climbing activity was observed in flies treated with sodium fluoride as compared to normal (control) flies. Flies treated with tulsi (Ocimum sanctum) and NaF showed increase in lifespan and climbing activity as compared to those treated with NaF only. Lipid peroxidation assay showed significant increase in malondialdehyde (MDA) values in the flies treated with NaF as compared to control. The MDA values decreased significantly in flies treated with tulsi mixed with NaF. Conclusions The results indicate that exposure to sub lethal concentration of NaF may cause oxidative stress and affect the lifespan and climbing activity of D. melanogaster. Tulsi extract may help in reducing the impact of oxidative stress and toxicity caused by NaF.

Oxidative stress and decreased dopamine levels induced by imidacloprid exposure cause behavioral changes in a neurodevelopmental disorder model in Drosophila melanogaster

2021 ◽  
Author(s):  
Dieniffer Espinosa Janner ◽  
Nathalie Savedra Gomes ◽  
Márcia Rósula Poetini ◽  
Kétnne Hanna Poleto ◽  
Elize Aparecida Santos Musachio ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Neurodevelopmental Disorder ◽  
Behavioral Changes

Oxidative stress caused by lead (Pb) induces iron deficiency in Drosophila melanogaster

Chemosphere ◽  
2020 ◽  
Vol 243 ◽  
pp. 125428 ◽  
Author(s):  
Zhi-Hua Liu ◽  
Jin Shang ◽  
Lailai Yan ◽  
Tian Wei ◽  
Ling Xiang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Iron Deficiency

The Effects of Age on Radiation Resistance and Oxidative Stress in Adult Drosophila melanogaster

2008 ◽  
Vol 169 (6) ◽  
pp. 707-711 ◽  
Author(s):  
Vijay Parashar ◽  
Stewart Frankel ◽  
Alan G. Lurie ◽  
Blanka Rogina
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Radiation Resistance ◽  
And Oxidative Stress ◽  
Adult Drosophila

Metabolomic analysis of oxidative stress: Superoxide dismutase mutation and paraquat induced stress in Drosophila melanogaster

2017 ◽  
Vol 113 ◽  
pp. 323-334 ◽  
Author(s):  
Marney L. Doran ◽  
Jose M. Knee ◽  
Nan Wang ◽  
Teresa Z. Rzezniczak ◽  
Tony L. Parkes ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Drosophila Melanogaster ◽  
Metabolomic Analysis ◽  
Induced Stress
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