The L-amino acid oxidase from Calloselasma rhodostoma snake venom modulates apoptomiRs expression in Bcr-Abl-positive cell lines

Toxicon ◽  
2016 ◽  
Vol 120 ◽  
pp. 9-14 ◽  
Author(s):  
Sandra Mara Burin ◽  
Maria Gabriela Berzoti-Coelho ◽  
Juçara Gastaldi Cominal ◽  
Luciana Ambrosio ◽  
Maria Regina Torqueti ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cell Lines ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Calloselasma Rhodostoma

scholarly journals l-Amino acid oxidase isolated from Calloselasma rhodostoma snake venom induces cytotoxicity and apoptosis in JAK2V617F-positive cell lines

2016 ◽  
Vol 38 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Cristiane Tavares ◽  
Thaís Maciel ◽  
Sandra Burin ◽  
Luciana Ambrósio ◽  
Sandro Ghisla ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cell Lines ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Calloselasma Rhodostoma

l-Amino acid oxidase from Cerastes vipera snake venom: Isolation, characterization and biological effects on bacteria and tumor cell lines

Toxicon ◽  
2018 ◽  
Vol 150 ◽  
pp. 270-279 ◽  
Author(s):  
Walaa H. Salama ◽  
Nihal M. Ibrahim ◽  
Amr E. El Hakim ◽  
Roqaya I. Bassuiny ◽  
Manal M. Mohamed ◽  
...  
Keyword(s):  
Amino Acid ◽  
Tumor Cell ◽  
Cell Lines ◽  
Snake Venom ◽  
Biological Effects ◽  
Acid Oxidase ◽  
Tumor Cell Lines ◽  
Amino Acid Oxidase

Impairment of Platelet Aggregation by Echis colorata Venom Mediated by L-Amino Acid Oxidase or H2O2

1982 ◽  
Vol 48 (03) ◽  
pp. 277-282 ◽  
Author(s):  
I Nathan ◽  
A Dvilansky ◽  
T Yirmiyahu ◽  
M Aharon ◽  
A Livne
Keyword(s):  
Hydrogen Peroxide ◽  
Amino Acid ◽  
Platelet Aggregation ◽  
Snake Venom ◽  
Oxidase Activity ◽  
Enzyme Preparation ◽  
Acid Oxidase ◽  
Crude Venom ◽  
Amino Acid Oxidase ◽  
Hemostatic Disorders

SummaryEchis colorata bites cause impairment of platelet aggregation and hemostatic disorders. The mechanism by which the snake venom inhibits platelet aggregation was studied. Upon fractionation, aggregation impairment activity and L-amino acid oxidase activity were similarly separated from the crude venom, unlike other venom enzymes. Preparations of L-amino acid oxidase from E.colorata and from Crotalus adamanteus replaced effectively the crude E.colorata venom in impairment of platelet aggregation. Furthermore, different treatments known to inhibit L-amino acid oxidase reduced in parallel the oxidase activity and the impairment potency of both the venom and the enzyme preparation. H2O2 mimicked characteristically the impairment effects of L-amino acid oxidase and the venom. Catalase completely abolished the impairment effects of the enzyme and the venom. It is concluded that hydrogen peroxide formed by the venom L-amino acid oxidase plays a role in affecting platelet aggregation and thus could contribute to the extended bleeding typical to persons bitten by E.colorata.

scholarly journals Role of l-amino acid oxidase isolated from Calloselasma rhodostoma venom on neutrophil NADPH oxidase complex activation

Toxicon ◽  
2018 ◽  
Vol 145 ◽  
pp. 48-55 ◽  
Author(s):  
Mauro Valentino Paloschi ◽  
Charles Nunes Boeno ◽  
Jéssica Amaral Lopes ◽  
André Eduardo dos Santos da Rosa ◽  
Weverson Luciano Pires ◽  
...  
Keyword(s):  
Amino Acid ◽  
Nadph Oxidase ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Nadph Oxidase Complex ◽  
Calloselasma Rhodostoma

Insights into the structure, function and stability of bordonein-L, the first L-amino acid oxidase from Crotalus durissus terrificus snake venom

Biochimie ◽  
2019 ◽  
Vol 163 ◽  
pp. 33-49 ◽  
Author(s):  
Gisele A. Wiezel ◽  
Joane K. Rustiguel ◽  
David Morgenstern ◽  
Karina F. Zoccal ◽  
Lucia H. Faccioli ◽  
...  
Keyword(s):  
Amino Acid ◽  
Structure Function ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Crotalus Durissus Terrificus ◽  
Crotalus Durissus
Sign in / Sign up

Export Citation Format

Share Document