Potential involvement of Fgf10/Fgfr2 and androgen receptor (AR) in renal fibrosis in adult male rat offspring subjected to prenatal exposure to di- n -butyl phthalate (DBP)

2018 ◽  
Vol 282 ◽  
pp. 37-42 ◽  
Author(s):  
Wen-Lan Sun ◽  
Yi-Ping Zhu ◽  
Xiu-Shi Ni ◽  
Da-Dao Jing ◽  
Yu-Ting Yao ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Prenatal Exposure ◽  
Adult Male ◽  
Renal Fibrosis ◽  
Male Rat ◽  
Rat Offspring ◽  
Adult Male Rat ◽  
Butyl Phthalate

scholarly journals Maternal tobacco smoke increased visceral adiposity and serum corticosterone levels in adult male rat offspring

2014 ◽  
Vol 76 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Erin K. Zinkhan ◽  
Brook Y. Lang ◽  
Baifeng Yu ◽  
Yan Wang ◽  
Chengshe Jiang ◽  
...  
Keyword(s):  
Adult Male ◽  
Tobacco Smoke ◽  
Visceral Adiposity ◽  
Male Rat ◽  
Serum Corticosterone ◽  
Rat Offspring ◽  
Adult Male Rat

Prenatal fluoxetine impairs non-hippocampal but not hippocampal memory in adult male rat offspring

2021 ◽  
pp. 108751
Author(s):  
Rodrigo Moraga-Amaro ◽  
Raul Díaz-Galarce ◽  
Juan P. Donoso-Ramos ◽  
Valentina Ugalde ◽  
Sergio Linsambarth ◽  
...  
Keyword(s):  
Adult Male ◽  
Male Rat ◽  
Rat Offspring ◽  
Adult Male Rat

scholarly journals Long-Term Consequences of Neonatal Rearing on Central Corticotropin-Releasing Factor Systems in Adult Male Rat Offspring

2005 ◽  
Vol 30 (12) ◽  
pp. 2192-2204 ◽  
Author(s):  
Paul M Plotsky ◽  
K V Thrivikraman ◽  
Charles B Nemeroff ◽  
Christian Caldji ◽  
Shakti Sharma ◽  
...  
Keyword(s):  
Adult Male ◽  
Corticotropin Releasing Factor ◽  
Male Rat ◽  
Rat Offspring ◽  
Adult Male Rat ◽  
Long Term Consequences

scholarly journals Maternal Exposure to Iodine Excess Throughout Pregnancy and Lactation Induces Hypothyroidism in Adult Male Rat Offspring

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Caroline Serrano-Nascimento ◽  
Rafael Barrera Salgueiro ◽  
Thiago Pantaleão ◽  
Vânia Maria Corrêa da Costa ◽  
Maria Tereza Nunes
Keyword(s):  
Adult Male ◽  
Maternal Exposure ◽  
Male Rat ◽  
Iodine Excess ◽  
Rat Offspring ◽  
Adult Male Rat ◽  
Pregnancy And Lactation

Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring

2017 ◽  
Vol 8 (1) ◽  
pp. 3-7 ◽  
Author(s):  
S. Lecoutre ◽  
L. Marousez ◽  
A. Drougard ◽  
C. Knauf ◽  
C. Guinez ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Adult Male ◽  
Messenger Rna ◽  
Leptin Receptor ◽  
Female Rats ◽  
Male Rat ◽  
Mrna Levels ◽  
Maternal Undernutrition ◽  
Rat Offspring ◽  
Adult Male Rat

Based on the Developmental Origin of Health and Disease concept, maternal undernutrition has been shown to sensitize adult offspring to metabolic pathologies such as obesity. Using a model of maternal 70% food restriction in pregnant female rats throughout gestation (called FR30), we previously reported that obesity-prone adult male rat offspring displayed hyperleptinemia with modifications in leptin and leptin receptor messenger RNA (mRNA) levels in white adipose tissue (WAT). Apelin is a member of the adipokine family that regulates various aspects of energy metabolism and WAT functionality. We investigated whether apelin and its receptor APJ could be a target of maternal undernutrition. Adult male rat offspring from FR30 dams showed increased plasma apelin levels and apelin gene expression in WAT. Post-weaning high-fat diet led to marked increase in APJ mRNA and protein levels in offspring’s WAT. We demonstrate that maternal undernutrition and post-weaning diet have long-term consequences on the apelinergic system of adult male rat offspring.

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