Relationship Between Vitamin D Blood Levels and Cancer Development in Renal Transplant Patients: A Case-Control Study

Abstract Background: In spite of effective anti-viral drugs and risk-balanced prophylaxis regimen, cytomegalovirus (CMV) remains a major reason of morbidity in kidney transplant patients. The aim of present study was to evaluate CMV viral load and laboratory findings correlation with CMV viremia graft origin and investigation on late or early onset CMV infection in kidney transplant recipients with CMV viremia. Methods: This research designed as a prospective case-control study based on CMV PCR test and exclusion of other viral infection among renal transplant patients in Iran.Results: From 192 examined patients, 153 participants were qualified to enter the study: 43 in case (with CMV viremia) and 110 in control group (CMV negative test). Statistical analysis performed to identify the risk factors raising this viral viremia among kidney transplant patients. Conclusion: Receiving a renal graft from a deceased donor significantly raise the chance of viremia in renal transplant patients. The median month of CMV viremia occurrence was month 4 after transplantation in both groups. Serum laboratory testing showed creatinine and platelets significantly raised and reduced, retrospectively in the case compare to control group. Our results indicating the viremia has not affected the survival of the allograft or patient.

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Vitamin D and cinacalcet administration pre-transplantation predict hypercalcaemic hyperparathyroidism post-transplantation: a case-control study of 355 deceased-donor renal transplant recipients over 3 years

Transplantation Research ◽

10.1186/s13737-014-0021-5 ◽

2014 ◽

Vol 3 (1) ◽

Cited By ~ 5

Author(s):

Frank-Peter Tillmann ◽

Carolin Wächtler ◽

Anita Hansen ◽

Lars Christian Rump ◽

Ivo Quack

Keyword(s):

Vitamin D ◽

Renal Transplant ◽

Case Control Study ◽

Deceased Donor ◽

Case Control ◽

Renal Transplant Recipients ◽

Transplant Recipients ◽

Post Transplantation ◽

Control Study

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Study of blood levels of Lactate, Vitamin D and Nucleated Red Blood Cells for early prediction of Hypoxic–Ischemic Encephalopathy: A cross-sectional case-control study

10.21203/rs.3.rs-268008/v1 ◽

2021 ◽

Author(s):

Ahmed Saad ◽

Ahmed thabet ◽

Mohamed Soliman ◽

Alyaa Abdel-Aziz

Keyword(s):

Vitamin D ◽

Blood Cells ◽

Case Control Study ◽

Case Control ◽

Control Group ◽

Blood Levels ◽

P Value ◽

Cross Sectional ◽

Nucleated Red Blood Cells ◽

Control Study

Abstract Background Perinatal asphyxia is a serious medical condition in which there is a lack of oxygen or blood flow during, or even after the labor process. Methods A cross-sectional case-control study was conducted on 20 neonates with HIE comprising the cases (APGAR ≤ 5) and another 20 neonates representing the control group with their age, sex, and weight matched, admitted to NICU. Sarnat score was used to assess the severity of HIE. Results Venous blood levels of lactate and nucleated red blood cells per 100 white blood cells (NRBC/100 WBC) counts were significantly higher in HIE neonates than in the control group with a highly significant difference (p-value < 0.001). While serum Vitamin D was significantly lower in the HIE group than in the control (p-value < 0.001). Conclusion Serum lactate level, vitamin D level and NRBCs/100 WBCs might be used as biomarkers in the early prediction of HIE.

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