PigThe relationship between food deprivation and blood glucose at induction of anaesthesia in juvenile pigs

2021 ◽  
Vol 48 (6) ◽  
pp. S981-S982
Author(s):  
R. Gregson ◽  
S. Greenhalgh ◽  
E. Clutton
Keyword(s):  
Blood Glucose ◽  
Food Deprivation ◽  
Induction Of Anaesthesia

Effects of Sleep or Food Deprivation During Civilian Survival Training on Cognition, Blood Glucose and 3-OH-butyrate

2011 ◽  
Vol 22 (3) ◽  
pp. 202-210 ◽  
Author(s):  
Lars Ståhle ◽  
Ewa Ljungdahl Ståhle ◽  
Elisabeth Granström ◽  
Sven Isaksson ◽  
Peter Annas ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Food Deprivation

scholarly journals Effects of fasting and refeeding on the metabolic functions of the turtle Kinosternon scorpioides (Linnaeus, 1766) raised in captivity

2013 ◽  
Vol 33 (8) ◽  
pp. 1041-1044 ◽  
Author(s):  
Antonia S. Oliveira ◽  
Cinthia G. Candioto ◽  
Débora M.S. Santos ◽  
José G. Pereira ◽  
Alana L. Sousa ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Food Deprivation ◽  
Muscle Glycogen ◽  
Blood Glucose Concentration ◽  
Liver Lipid ◽  
Liver Glycogen ◽  
In Captivity ◽  
Fasting And Refeeding ◽  
The One ◽  
Muscle Lipids

The metabolic responses of adult and young freshwater Kinosternon scorpioides turtles raised in captivity were evaluated. Two experiments were performed: a) blood metabolite changes caused by food deprivation, and b) liver and muscle glycogen and total lipid differences after fasting and refeeding. Blood glucose concentration of young animals was susceptible to food deprivation. In both groups this metabolite decreased after 30 days of fasting. Feeding for 15 days did not recover blood glucose. Total seric proteins were not affected by food deprivation. Fasting decreased blood urea nitrogen and the highest difference was found around 30 days. Uric acid increased in young animals after 60 days of fasting. Triacylglicerol decreased after 15 days of fasting and refeeding for 15 days recovered the pre-fasting levels. Free fatty acid plasma tended to increase around 15 days of fasting. Liver glycogen decreased at day 15 of fasting, being stable thereafter while muscle glycogen decreased at a slower rate. Total liver lipid stabilized after 30 days and then decreased 70% after 60 days of fasting. Muscle lipids remained stable throughout fasting. It could be concluded that fasting of Kinosternon scorpioides led to metabolic adaptations similar to the one reported from reptiles and fish.

scholarly journals Effects in vivo of food deprivation and 3-mercaptopicolinate in the glycogen-storage-disease (gsd/gsd) rat

1985 ◽  
Vol 231 (3) ◽  
pp. 755-759 ◽  
Author(s):  
D G Clark ◽  
M Brinkman ◽  
S D Neville ◽  
W D Haynes
Keyword(s):  
Blood Glucose ◽  
Food Deprivation ◽  
Intraperitoneal Injection ◽  
Storage Disease ◽  
Liver Glycogen ◽  
Glycogen Storage ◽  
Hepatic Glycogen ◽  
Glycogen Stores ◽  
Female Control

Intraperitoneal injection of 3-mercaptopicolinate into 24 h-food-deprived 27-week-old female control (GSD/GSD) rats lowered the concentration of circulating glucose by 66%, but glycerol and lactate concentrations were increased up to 3- and 4-fold respectively. In phosphorylase b kinase-deficient (gsd/gsd) rats the corresponding changes for blood glucose, lactate and glycerol were half those observed in the controls. Although the concentration of liver glycogen (approx. 12%, w/w) in the gsd/gsd rats was not altered during food deprivation, total hepatic glycogen was decreased by 17%. It is suggested that the gradual breakdown of the extensive hepatic glycogen stores during starvation assists in the maintenance of normoglycaemia in the gsd/gsd rat.

scholarly journals Comparison of Esmolol and Dexmedetomidine Infusion in Attenuating Haemodynamic and Blood Glucose Response to Laryngoscopy and Intubation: A Single Blinded Study

2021 ◽  
Vol 28 (3) ◽  
pp. 46-55
Author(s):  
Vincent Koh ◽  
Saedah Ali ◽  
Mohamad Hasyizan Hassan ◽  
Ariffin Marzuki Mokhtar ◽  
Mohd Najib Majdi Yaacob ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Repeated Measures ◽  
Group Differences ◽  
Control Group ◽  
Significant Treatment ◽  
Glucose Response ◽  
Significant Time ◽  
Blinded Study ◽  
Post Intubation ◽  
Induction Of Anaesthesia

Background: This study aims to compare the effect of infusions of two agents, dexmedetomidine and esmolol, with the control group in attenuating the haemodynamic stress response and neuroendocrine modulation surrogated by capillary blood glucose (BG) during the procedures. Methods: Sixty patients aged 18–70 years old who underwent elective surgeries involving endotracheal intubation were randomised into three groups of equal size: i) control; ii) dexmedetomidine and iii) esmolol. Heart rate (HR) was measured at baseline (T0), after drug administration (T1), after induction of anaesthesia (T2), immediately after intubation (T3), and 3 min, 5 min and 10 min after intubation (T4, T5 and T6). BG was measured pre-operatively and 30 min post-intubation. Results: Two-way repeated-measures analysis of variance showed significant time [within- group changes, F(3.2, 182.5) = 30.39, P < 0.001], treatment [between-group differences regardless of time, F(2, 57) = 50.24, P < 0.001] and interaction [between-group differences based on time, F(6.4, 182.5) = 37.65, P < 0.001] effects on HR. A significantly higher HR was observed in the control group compared to the dexmedetomidine and esmolol groups from T2 to T6. BG exhibited a significant time effect [F(1, 57) = 41.97, P < 0.001] with no significant treatment and interaction effects. All three groups showed a significant increase in BG from baseline. Conclusion: Both dexmedetomidine and esmolol are equally effective in attenuating haemodynamic responses to laryngoscopy and intubation. However, both do not significantly modulate neuroendocrine stress.

Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice

2010 ◽  
Vol 109 (3) ◽  
pp. 692-701 ◽  
Author(s):  
David L. Allen ◽  
Allison S. Cleary ◽  
Sarah F. Lindsay ◽  
Amanda S. Loh ◽  
Jason M. Reed
Keyword(s):  
Blood Glucose ◽  
Muscle Mass ◽  
Food Deprivation ◽  
Muscle Atrophy ◽  
Similar Amount ◽  
Mrna Levels ◽  
Wild Type ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Fast Twitch

During food deprivation (FD), skeletal muscle protein is broken down to produce amino acids for hepatic gluconeogenesis to maintain blood glucose levels. However, it is unclear what role, if any, the secreted antigrowth factor myostatin (MSTN) plays in the muscle atrophy induced by FD. We therefore examined expression and function of MSTN in FD in mice. Two days of FD significantly decreased muscle mass and protein content and increased mRNA levels of ubiquitin ligases MuRF-1 and atrogin-1 in fast-twitch tibialis anterior (TA) muscle but not slow-twitch soleus (Sol) muscle, while 2 days of refeeding returned these to fed values in TA. MSTN mRNA levels were significantly increased approximately threefold by 2 days, but not 1 day, of FD and returned to fed levels with 2 days of refeeding in TA but were not significantly affected by FD or refeeding in Sol. TA mass decreased to a similar amount after 1 day of FD in wild-type mice and mice null for the MSTN gene but was decreased to a greater amount in wild-type than MSTN-null mice by 2 days of FD. In addition, blood glucose levels decreased and corticosterone levels increased to a greater extent in MSTN-null mice after 2 days of FD, but surprisingly muscle MuRF-1 and atrogin-1 mRNA levels were not affected by the lack of MSTN during FD. Similarly, changes in hepatic enzyme expression in response to FD were identical between wild-type and MSTN-null mice. Our data are consistent with the hypothesis that MSTN is dispensable for the initial atrophy occurring in response to FD but attenuates the decrease in fast-twitch muscle mass during prolonged FD.

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