scholarly journals Protocol for assessing the role of hippocampal perineuronal nets in aversive memories

2021 ◽  
Vol 2 (4) ◽  
pp. 100931
Author(s):  
Vladimir Jovasevic ◽  
Hui Zhang ◽  
Zorica Petrovic ◽  
Ana Cicvaric ◽  
Jelena Radulovic
Keyword(s):  
Perineuronal Nets

Stability and Collapsing Mechanism of Cavitation-Induced Nanobubbles in Simulated Extra-Cellular Matrix (ECM) Near Neuron

2016 ◽  
Author(s):  
Y.-T. Wu ◽  
A. Adnan
Keyword(s):  
Extra Cellular Matrix ◽  
Bubble Collapse ◽  
Experimental Investigations ◽  
Perineuronal Nets ◽  
Neuron Damage ◽  
The Stability ◽  
The Relationship ◽  
Fluid Interaction ◽  
Cellular Matrix

In blast-induced traumatic brain injury, shock waves (SW) play an important role along with cavitation phenomena. Due to the lack of reliable and reproducible experimental investigations, we have a limited understanding of the role of cavitation in brain damage. The present study aims to develop an atomistic simulation model to determine the role of shock-induced impulse and different constituents of the brain’s extra-cellular matrix (ECM) on the formation mechanism, stability and collapsing mechanism of nanobubbles in the ECM. The ECM in the brain can be divided into three major types depending on their location behind the blood-brain barrier, namely (a) the basement membrane (basal lamina), (b) the perineuronal nets and (3) the neural interstitial matrix. In this paper, we have studied the interaction of nanobubbles with bio-molecules of the perineuronal nets. We have chosen this zone of the ECM because we are interested to obtain the role of cavitation bubble collapse in neuron damage. Most biomolecules of perineuronal nets are slender in shape and flexible which is believed to induce special solid-fluid interaction between the fluid domain and the solid domain within the ECM. In addition, perineuronal nets contain a significant number of sodium ions. The relationship between sodium ion and solid-like constituents of perineuronal nets on the stability and the collapsing mechanism of nanobubbles will be discussed.

scholarly journals Saccadic Palsy following Cardiac Surgery: Possible Role of Perineuronal Nets

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0132075 ◽  
Author(s):  
Scott D. Z. Eggers ◽  
Anja K. E. Horn ◽  
Sigrun Roeber ◽  
Wolfgang Härtig ◽  
Govind Nair ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Perineuronal Nets

scholarly journals Semaphorins in Adult Nervous System Plasticity and Disease

2021 ◽  
Vol 13 ◽  
Author(s):  
Daniela Carulli ◽  
Fred de Winter ◽  
Joost Verhaagen
Keyword(s):  
Nervous System ◽  
Critical Period ◽  
Synapse Formation ◽  
Perineuronal Nets ◽  
Semaphorin 3A ◽  
Neuronal Proliferation ◽  
And Migration ◽  
Semaphorin 5A ◽  
Proliferation And Migration

Semaphorins, originally discovered as guidance cues for developing axons, are involved in many processes that shape the nervous system during development, from neuronal proliferation and migration to neuritogenesis and synapse formation. Interestingly, the expression of many Semaphorins persists after development. For instance, Semaphorin 3A is a component of perineuronal nets, the extracellular matrix structures enwrapping certain types of neurons in the adult CNS, which contribute to the closure of the critical period for plasticity. Semaphorin 3G and 4C play a crucial role in the control of adult hippocampal connectivity and memory processes, and Semaphorin 5A and 7A regulate adult neurogenesis. This evidence points to a role of Semaphorins in the regulation of adult neuronal plasticity. In this review, we address the distribution of Semaphorins in the adult nervous system and we discuss their function in physiological and pathological processes.

scholarly journals Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

2016 ◽  
Vol 36 (45) ◽  
pp. 11459-11468 ◽  
Author(s):  
Barbara A. Sorg ◽  
Sabina Berretta ◽  
Jordan M. Blacktop ◽  
James W. Fawcett ◽  
Hiroshi Kitagawa ◽  
...  
Keyword(s):  
Neural Plasticity ◽  
Perineuronal Nets

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management

The power of norms to sway fused group members

2018 ◽  
Vol 41 ◽  
Author(s):  
Winnifred R. Louis ◽  
Craig McGarty ◽  
Emma F. Thomas ◽  
Catherine E. Amiot ◽  
Fathali M. Moghaddam
Keyword(s):  
Evolutionary Anthropology ◽  
Normative Systems ◽  
Violent Extremism ◽  
Identity Fusion ◽  
Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

Elaborating the role of reflection and individual differences in the study of folk-economic beliefs

2018 ◽  
Vol 41 ◽  
Author(s):  
Kevin Arceneaux
Keyword(s):  
Decision Making ◽  
Individual Differences ◽  
Cognitive Processes ◽  
Evolutionary History ◽  
Behavioral Responses ◽  
History Of ◽  
Economic Beliefs

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.

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