Factors affecting the incidence of postoperative septic complications and recurrence after strictureplasty for jejunoileal crohn’s disease

1999 ◽  
Vol 178 (3) ◽  
pp. 240-245 ◽  
Author(s):  
Takayuki Yamamoto ◽  
Michael R.B Keighley
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Septic Complications ◽  
Factors Affecting ◽  
Postoperative Septic Complications

Influence of percutaneous abscess drainage on severe postoperative septic complications in patients with Crohn's disease

2011 ◽  
Vol 26 (6) ◽  
pp. 769-774 ◽  
Author(s):  
René Müller-Wille ◽  
Igors Iesalnieks ◽  
Christian Dornia ◽  
Claudia Ott ◽  
Ernst Michael Jung ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Abscess Drainage ◽  
Septic Complications ◽  
Percutaneous Abscess Drainage ◽  
Postoperative Septic Complications

Relationship of postoperative septic complications and blood transfusions in patients with Crohn's disease

1988 ◽  
Vol 155 (1) ◽  
pp. 43 ◽  
Author(s):  
Paul I. Tartter ◽  
Ronald M. Driefuss ◽  
Andrea M. Malon ◽  
Tomas M. Heimann ◽  
Arthur H. Aufses
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Blood Transfusions ◽  
Septic Complications ◽  
Relationship Of ◽  
Postoperative Septic Complications

scholarly journals High risk of septic complications following surgery for Crohn's disease in patients with preoperative anaemia, hypoalbuminemia and high CRP

2019 ◽  
Vol 34 (12) ◽  
pp. 2185-2188 ◽  
Author(s):  
Ahmed S. Ghoneima ◽  
Karen Flashman ◽  
Victoria Dawe ◽  
Eleanor Baldwin ◽  
Valerio Celentano
Keyword(s):  
Crohn’S Disease ◽  
High Risk ◽  
Crohn's Disease ◽  
Clinical Decision Making ◽  
Bowel Resection ◽  
Risk Group ◽  
Haemoglobin Concentration ◽  
Low Risk ◽  
Septic Complications ◽  
Risk Patients

Abstract Aim Bowel resection in Crohn's disease still has a high rate of complications due to risk factors including immune suppression, malnutrition and active inflammation or infection at the time of operating. In this study, we use serological levels and inflammatory markers to predict the potential of complications in patients undergoing resections for complicated Crohn's disease. Methods All patients undergoing laparoscopic bowel resection for Crohn’s disease from 5th of November 2012 to 11th of October 2017 were included in this retrospective observational study. Patients were divided into 4 groups scoring 0, 1, 2 or 3 depending on their pre-operative haemoglobin concentration (Hb), C-reactive protein (CRP) and albumin (Alb) where 1 point was given for an abnormal value in each as detailed in the definitions. They were then grouped into a low risk group comprised of those scoring 0 and 1, and a high risk group for those scoring 2 and 3 and data was collected to compare outcomes and the incidence of septic complications. Results Seventy-nine patients were included. Eleven (13.9%) and 2 (2.5%) patients had 2 or 3 abnormal values of CRP, Alb and Hb and were categorized as high risk. High risk patients had a significantly higher rate of post-operative septic complications (30.7%) compared with low risk patients (10.6%) p value < 0.0001. Conclusion Pre-operative CRP, haemoglobin and albumin can serve as predictors of septic complications after surgery for Crohn’s disease and can therefore be used to guide pre-operative optimisation and clinical decision-making.

scholarly journals Safety and Efficacy of Exclusive Enteral Nutrition for Percutaneously Undrainable Abdominal Abscesses in Crohn’s Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Yibin Zhu ◽  
Liang Xu ◽  
Wei Liu ◽  
Weilin Qi ◽  
Qian Cao ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Enteral Nutrition ◽  
Treatment Protocol ◽  
Albumin Level ◽  
Septic Complications ◽  
Safety And Efficacy ◽  
Exclusive Enteral Nutrition ◽  
Previous Abdominal Surgery ◽  
Abdominal Abscesses

Background. The percutaneously undrainable abdominal abscesses in Crohn’s disease (CD) are not uncommon. The treatment protocol is still under debate. This study was conducted to assess the safety and efficacy of exclusive enteral nutrition (EEN) for percutaneously undrainable abscesses in CD. Methods. A consecutive cohort of 83 CD patients with percutaneously undrainable abdominal abscesses between January 2011 and June 2015 was retrospectively analyzed. They were divided into the EEN group and the non-EEN group. Results. The cumulative surgical rate was significantly lower in the EEN group than in the non-EEN group (P=0.001). Fifteen percent patients treated with EEN avoided surgery. EEN (P=0.002) was associated with a decreased need for surgery. Previous abdominal surgery (P=0.009) and abscess diameter > 3 cm (P=0.022) were associated with an increased need for operation. EEN increased the albumin level, while decreased ESR and CRP significantly for patients requiring surgery. The risk of postoperative intra-abdominal septic complications (P=0.036) was significantly lower in the EEN group compared with the non-EEN group. Conclusions. EEN is feasible in CD patients presenting with percutaneously undrainable abdominal abscesses. It is associated with a reduction in surgical rate, optimized preoperative condition, and improved postoperative outcomes in these specific groups of patients.

Postoperative Interleukin-6 Predicts Intra-abdominal Septic Complications at an Early Stage After Elective Intestinal Operation for Crohn’s Disease Patients

2018 ◽  
Vol 24 (9) ◽  
pp. 1992-2000 ◽  
Author(s):  
Tingbin Xie ◽  
Chenyan Zhao ◽  
Chao Ding ◽  
Liang Zhang ◽  
Minhua Cheng ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Interleukin 6 ◽  
Early Stage ◽  
Septic Complications

scholarly journals Hypoalbuminaemia and Postoperative Outcomes in Inflammatory Bowel Disease: the NSQIP Surgical Cohort

2019 ◽  
Vol 13 (11) ◽  
pp. 1433-1438 ◽  
Author(s):  
Geoffrey C Nguyen ◽  
Lillian Du ◽  
Rachel Y Chong ◽  
Timothy D Jackson
Keyword(s):  
Ulcerative Colitis ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Postoperative Outcomes ◽  
Improvement Program ◽  
Septic Complications ◽  
Bowel Surgery ◽  
Inflammatory Bowel ◽  
The Impact ◽  
Normal Albumin

Abstract Background The inflammatory bowel diseases [IBD], including Crohn’s disease [CD] and ulcerative colitis [UC], frequently lead to bowel surgery. Hypoalbuminaemia has been shown to be a prognostic factor for outcomes following surgery for other indications, and we sought to determine its role in predicting IBD-related postoperative outcomes. Methods We included patients who underwent IBD-related major abdominal surgery in the American College of Surgeons’ National Surgical Quality Improvement Program [ACS-NSQIP] between 2005 and 2012. We assessed the impact of indicators of protein-energy malnutrition [PEM] including hypoalbuminaemia, weight loss, and body mass index on postoperative outcomes. Results We identified 10 913 IBD patients [6082 Crohn’s disease and 4831 ulcerative colitis] who underwent bowel surgery. The prevalence of modest and severe hypoalbuminaemia was 17% and 24%, respectively; 30-day mortality was higher in Crohn’s patients with modest and severe hypoalbuminaemia compared with those with normal albumin levels preoperatively [0.7% vs 0.2%, p <0.05; 2.4% vs 0.2%, p <0.01]. The same was true for patients with UC with modest and severe hypoalbuminaemia [0.9% vs 0.1%, p <0.01; 5.6% vs 0.1%, p <0.01]. Overall infectious complications were more common in the presence of severe hypoalbuminaemia for CD [20% vs 13%, p <0.01]. and UC [28% vs 15%, p <0.01] patients. Last, there were higher rates of extra-intestinal, non-septic complications in both CD and UC patients with hypoalbuminaemia compared with those with normal albumin levels. Conclusions This study suggests that moderate-severe hypoalbuminaemia is associated with worse IBD-related postoperative outcomes and may have a role in preoperative risk stratification.

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