Frontal lobe dysfunction of schizophrenia on 1H MRS and neuropsychological test

1997 ◽  
Vol 42 (1) ◽  
pp. 65S-66S
Author(s):  
C.U. Lee ◽  
I.H. Paik ◽  
C. Lee ◽  
S.J. Lee ◽  
J.J. Kim ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Neuropsychological Test ◽  
Frontal Lobe Dysfunction ◽  
1H Mrs

scholarly journals Differences in Frontal Lobe Dysfunction in Patients with Episodic and Chronic Migraine

2021 ◽  
Vol 10 (13) ◽  
pp. 2779
Author(s):  
Sang-Hwa Lee ◽  
Yeonkyeong Lee ◽  
Minji Song ◽  
Jae Jun Lee ◽  
Jong-Hee Sohn
Keyword(s):  
Chronic Migraine ◽  
Frontal Lobe ◽  
Iowa Gambling Task ◽  
Medication Overuse Headache ◽  
Wisconsin Card Sorting Test ◽  
Episodic Migraine ◽  
Frontal Lobe Dysfunction ◽  
Card Sorting ◽  
Cross Sectional ◽  
Frontal Lobe Function

Neuroimaging and neuropsychological investigations have indicated that migraineurs exhibit frontal lobe-related cognitive impairment. We investigated whether orbitofrontal and dorsolateral functioning differed between individuals with episodic migraine (EM) and chronic migraine (CM), focusing on orbitofrontal dysfunction because it is implicated in migraine chronification and medication overuse headache (MOH) in migraineurs. This cross-sectional study recruited women with CM with/without MOH (CM + MOH, CM − MOH), EM, and control participants who were matched in terms of age and education. We conducted neuropsychological assessments of frontal lobe function via the Trail Making Test (TMT) A and B, the Wisconsin Card Sorting Test (WCST), and the Iowa Gambling Task (IGT). We enrolled 36 CM (19 CM + MOH, 17 CM–MOH), 30 EM, and 30 control participants. The CM patients performed significantly (p < 0.01) worse on the TMT A and B than the EM patients and the control participants. The WCST also revealed significant differences, with poorer performance in the CM patients versus the EM patients and the control participants. However, the net scores on the IGT did not significantly differ among the three groups. Our findings suggest that the CM patients exhibited frontal lobe dysfunction, and, particularly, dorsolateral dysfunction. However, we found no differences in frontal lobe function according to the presence or absence of MOH.

scholarly journals Mother and daughter with adolescent-onset severe frontal lobe dysfunction and epilepsy

2016 ◽  
Vol 10 (3) ◽  
pp. 238-243
Author(s):  
Giordani Rodrigues dos Passos ◽  
Alonso Cuadrado Fernández ◽  
Adriana Machado Vasques ◽  
William Alves Martins ◽  
André Palmini
Keyword(s):  
Frontal Lobe ◽  
Early Onset ◽  
Frontal Lobe Dysfunction ◽  
Genetic Condition ◽  
Familial Cases ◽  
Mother And Daughter

ABSTRACT Familial cases of early-onset prominent frontal lobe dysfunction associated with epilepsy have not been reported to date. We report a mother and her only daughter with incapacitating behavioral manifestations of frontal lobe dysfunction and epilepsy of variable severity. The possibility of a hitherto undescribed genetic condition is discussed.

Recognition and its Impairment regarding Autobiographical Memories in a Patient with Hippocampal Amnesia

2007 ◽  
Vol 101 (3) ◽  
pp. 796-802
Author(s):  
Mikio Hirano ◽  
Toshihiko Kikuchi ◽  
Ayumu Goukon ◽  
Kazuhito Noguchi ◽  
Toru Hosokawa
Keyword(s):  
Frontal Lobe ◽  
Male Patient ◽  
Semantic Information ◽  
Recognition Performance ◽  
Amnesic Patient ◽  
Frontal Lobe Dysfunction ◽  
Autobiographical Memories ◽  
Before And After

Autobiographical memories of one case (Y.K.) were assessed before and after onset of hippocampal amnesia. He was a 56-yr.-old male patient who used to work in an office. The findings can be described as follows. First, Y.K.‘s recognition performance regarding his premorbid and postmorbid personal semantics along with premorbid autobiographical incidents was significantly greater than chance, and recognition of premorbid autobiographical incidents was within chance. Given information before onset, a relationship was suspected between frontal lobe dysfunction and Y.K.‘s autobiographical problem. The possibility that an amnesic patient could acquire semantic information after onset is discussed.

FRONTAL LOBE DYSFUNCTION IN PARKINSON'S DISEASE

Brain ◽  
1986 ◽  
Vol 109 (5) ◽  
pp. 845-883 ◽  
Author(s):  
ANN E. TAYLOR ◽  
J. A. SAINT-CYR ◽  
A. E. LANG
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Frontal Lobe ◽  
Frontal Lobe Dysfunction

scholarly journals Value of the Frontal Assessment Battery Tool for Assessing the Frontal Lobe Function in Stroke Patients

2020 ◽  
Vol 44 (4) ◽  
pp. 261-272
Author(s):  
Mihyang Han ◽  
Da-Ye Kim ◽  
Ja-Ho Leigh ◽  
Min-Wook Kim
Keyword(s):  
Frontal Lobe ◽  
Mmse Score ◽  
Treatment Strategies ◽  
Correlation Coefficients ◽  
Imaging Study ◽  
Frontal Lobe Dysfunction ◽  
Frontal Assessment Battery ◽  
Stroke Patients ◽  
Assessment Battery ◽  
Frontal Lobe Function

Objective To examine the correlation between the Frontal Assessment Battery (FAB) test, which is used to assess the frontal lobe function, and anatomical lesions as well as the ability of the test to detect frontal lobe dysfunction.Methods Records of stroke patients undergoing a FAB test and Mini-Mental State Examination (MMSE) were retrospectively reviewed. The patients were divided into three groups according to the lesions determined by an imaging study: frontal lobe cortex lesions, frontal subcortical circuit lesions, and other lesions. The FAB scores of the three groups were compared using the Kruskal-Wallis test. The validity of the FAB test to detect frontal lobe dysfunction was assessed by a comparison with the Computerized Neuropsychological Function Test (CNT) using the Spearman correlation coefficient. The correlation coefficients between the FAB test and MMSE were analyzed further based on the MMSE cutoff score.Results Patients with frontal cortex lesions had significantly lower total and subtest scores according to the FAB test than the other patients. The FAB test correlated better with the CNT than the MMSE, particularly in the executive function and memory domains. A high MMSE score (r=0.435) indicated a lower correlation with the FAB test score than a low MMSE score (r=0.714).Conclusion The FAB test could differentiate frontal lobe lesions from others in stroke patients and showed a good correlation with the CNT. Moreover, the FAB test can be used in patients with high MMSE scores to detect frontal lobe dysfunction and determine the treatment strategies for stroke patients.

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