scholarly journals Value of the Frontal Assessment Battery Tool for Assessing the Frontal Lobe Function in Stroke Patients

2020 ◽  
Vol 44 (4) ◽  
pp. 261-272
Author(s):  
Mihyang Han ◽  
Da-Ye Kim ◽  
Ja-Ho Leigh ◽  
Min-Wook Kim
Keyword(s):  
Frontal Lobe ◽  
Mmse Score ◽  
Treatment Strategies ◽  
Correlation Coefficients ◽  
Imaging Study ◽  
Frontal Lobe Dysfunction ◽  
Frontal Assessment Battery ◽  
Stroke Patients ◽  
Assessment Battery ◽  
Frontal Lobe Function

Objective To examine the correlation between the Frontal Assessment Battery (FAB) test, which is used to assess the frontal lobe function, and anatomical lesions as well as the ability of the test to detect frontal lobe dysfunction.Methods Records of stroke patients undergoing a FAB test and Mini-Mental State Examination (MMSE) were retrospectively reviewed. The patients were divided into three groups according to the lesions determined by an imaging study: frontal lobe cortex lesions, frontal subcortical circuit lesions, and other lesions. The FAB scores of the three groups were compared using the Kruskal-Wallis test. The validity of the FAB test to detect frontal lobe dysfunction was assessed by a comparison with the Computerized Neuropsychological Function Test (CNT) using the Spearman correlation coefficient. The correlation coefficients between the FAB test and MMSE were analyzed further based on the MMSE cutoff score.Results Patients with frontal cortex lesions had significantly lower total and subtest scores according to the FAB test than the other patients. The FAB test correlated better with the CNT than the MMSE, particularly in the executive function and memory domains. A high MMSE score (r=0.435) indicated a lower correlation with the FAB test score than a low MMSE score (r=0.714).Conclusion The FAB test could differentiate frontal lobe lesions from others in stroke patients and showed a good correlation with the CNT. Moreover, the FAB test can be used in patients with high MMSE scores to detect frontal lobe dysfunction and determine the treatment strategies for stroke patients.

scholarly journals Frontal Assessment Battery to Evaluate Frontal Lobe Dysfunction in ALS Patients

2011 ◽  
Vol 38 (2) ◽  
pp. 242-246 ◽  
Author(s):  
Suk-Won Ahn ◽  
Su-Hyun Kim ◽  
Jee-Eun Kim ◽  
Sung-Min Kim ◽  
Seung Hyun Kim ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Disease Duration ◽  
Screening Method ◽  
Frontal Lobe Dysfunction ◽  
Frontal Assessment Battery ◽  
Assessment Battery ◽  
Sporadic Als ◽  
Frontal Lobe Impairment ◽  
Als Patients ◽  
State Examination

Background:Assessment of frontal lobe impairment in amyotrophic lateral sclerosis (ALS) is a matter of great importance, since it often causes ALS patients to decrease medication and nursing compliance, thus shortening their survival time.Methods:The frontal assessment battery (FAB) is a short and rapid method for assessing frontal executive functions. We investigated the applicability of the FAB as a screening method for assessing cognitive impairments in 61 ALS patients. Depending on the results of the FAB, we classified patients into two subgroups: FAB-normal and FAB-abnormal. We then performed additional evaluations of cognitive function using the Korean version of the mini-mental state examination (K-MMSE), a verbal fluency test (COWAT), and a neuropsychiatric inventory (NPI). Results of these tests were compared between the two groups using Mann-Whitney U-tests, and Spearman correlation analyses were used to investigate the relationships between FAB score and disease duration and severity.Results:Of the 61 sporadic ALS patients included in this study, 14 were classified as FAB-abnormal and 47 were classified as FAB-normal. The FAB-normal and FAB-abnormal patients performed significantly differently in all domains of the COWAT. There was no difference in behavioral disturbance, as assessed by the NPI, between the two groups. The FAB scores were found to significantly correlate with both disease duration and severity.Conclusions:The FAB shows promise as a method of screening for frontal lobe dysfunction in ALS, as it is not only quick and easy, but also reliable. Additional studies should examine how FAB performance changes as ALS progresses.

scholarly journals Assessing frontal lobe function in patients with amyotrophic lateral sclerosis by Frontal Assessment Battery

2010 ◽  
Vol 50 (6) ◽  
pp. 379-384 ◽  
Author(s):  
Tatsuhiro Terada ◽  
Tomokazu Obi ◽  
Hiroaki Miyajima ◽  
Kouichi Mizoguchi
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Frontal Lobe ◽  
Frontal Assessment Battery ◽  
Assessment Battery ◽  
Frontal Lobe Function ◽  
Lateral Sclerosis

scholarly journals Performance on the Frontal Assessment Battery is sensitive to frontal lobe damage in stroke patients

BMC Neurology ◽  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Bruno Kopp ◽  
Nina Rösser ◽  
Sandra Tabeling ◽  
Hans Jörg Stürenburg ◽  
Bianca de Haan ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Frontal Assessment Battery ◽  
Stroke Patients ◽  
Assessment Battery ◽  
Frontal Lobe Damage

The Frontal Assessment Battery as a Tool for Evaluation of Frontal Lobe Dysfunction in Patients With Parkinson Disease

2012 ◽  
Vol 25 (2) ◽  
pp. 71-77 ◽  
Author(s):  
Oren S. Cohen ◽  
Eli Vakil ◽  
David Tanne ◽  
Noa Molshatzki ◽  
Zeev Nitsan ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Frontal Lobe ◽  
Frontal Lobe Dysfunction ◽  
Frontal Assessment Battery ◽  
Assessment Battery

scholarly journals Differences in Frontal Lobe Dysfunction in Patients with Episodic and Chronic Migraine

2021 ◽  
Vol 10 (13) ◽  
pp. 2779
Author(s):  
Sang-Hwa Lee ◽  
Yeonkyeong Lee ◽  
Minji Song ◽  
Jae Jun Lee ◽  
Jong-Hee Sohn
Keyword(s):  
Chronic Migraine ◽  
Frontal Lobe ◽  
Iowa Gambling Task ◽  
Medication Overuse Headache ◽  
Wisconsin Card Sorting Test ◽  
Episodic Migraine ◽  
Frontal Lobe Dysfunction ◽  
Card Sorting ◽  
Cross Sectional ◽  
Frontal Lobe Function

Neuroimaging and neuropsychological investigations have indicated that migraineurs exhibit frontal lobe-related cognitive impairment. We investigated whether orbitofrontal and dorsolateral functioning differed between individuals with episodic migraine (EM) and chronic migraine (CM), focusing on orbitofrontal dysfunction because it is implicated in migraine chronification and medication overuse headache (MOH) in migraineurs. This cross-sectional study recruited women with CM with/without MOH (CM + MOH, CM − MOH), EM, and control participants who were matched in terms of age and education. We conducted neuropsychological assessments of frontal lobe function via the Trail Making Test (TMT) A and B, the Wisconsin Card Sorting Test (WCST), and the Iowa Gambling Task (IGT). We enrolled 36 CM (19 CM + MOH, 17 CM–MOH), 30 EM, and 30 control participants. The CM patients performed significantly (p < 0.01) worse on the TMT A and B than the EM patients and the control participants. The WCST also revealed significant differences, with poorer performance in the CM patients versus the EM patients and the control participants. However, the net scores on the IGT did not significantly differ among the three groups. Our findings suggest that the CM patients exhibited frontal lobe dysfunction, and, particularly, dorsolateral dysfunction. However, we found no differences in frontal lobe function according to the presence or absence of MOH.

Use of a Verbal Fluency Measure in Understanding and Evaluating Adhd as an Executive Function Disorder

1992 ◽  
Vol 75 (3_suppl) ◽  
pp. 1187-1192 ◽  
Author(s):  
Leonard F. Koziol ◽  
Chris E. Stout
Keyword(s):  
Frontal Lobe ◽  
Verbal Fluency ◽  
Frontal Lobe Dysfunction ◽  
Treatment Facility ◽  
Diagnostic Screening ◽  
Hyperactivity Disorder ◽  
Cohort Group ◽  
Attentional Process ◽  
Frontal Lobe Function ◽  
Adhd Children

A primary characteristic of Attention Deficit Hyperactivity Disorder (ADHD) is an inability to establish and maintain sustained attention, which is speculated to reflect frontal lobe involvement. The Knight Verbal Fluency measure was administered to 19 ADHD inpatient boys and to a cohort group of 7 children who were matched for mean age, psychiatric diagnosis (depression), treatment facility, and examiner but were without the diagnosis of ADHD. Analysis indicated that ADHD children performed significantly lower than expected and lower than the similar non-ADHD children. These findings lend support to the hypothesis that frontal lobe dysfunction is involved in attentional process disorders and suggests the potential clinical usefulness in the diagnostic screening of ADHD children of a simply administered measure amenable to interpretation of frontal lobe function.

scholarly journals Associations of Genetic Polymorphisms and Neuroimmune Markers With Some Parameters of Frontal Lobe Dysfunction in Schizophrenia

2021 ◽  
Vol 12 ◽  
Author(s):  
Anna Morozova ◽  
Yana Zorkina ◽  
Konstantine Pavlov ◽  
Olga Pavlova ◽  
Olga Abramova ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Rating Scale ◽  
Clinical Symptoms ◽  
Frontal Lobe Dysfunction ◽  
Reactive Protein ◽  
Frontal Lobe Damage ◽  
Syndrome Scale ◽  
Frontal Lobe Function ◽  
Negative Syndrome ◽  
Control Study

We investigated the associations of DRD3 rs6280, HTR1A rs6295, BDNF rs6265, SCL6A4 rs16965628, and 5HT2A rs7322347 with schizophrenia in a case–control study, and associations of these genetic variants with several clinical features. We also investigated markers of inflammatory response (C-reactive protein, IL-2, IL-6, IL-10), the activity of leukocytic elastase (LE) and α1-proteinase inhibitor (a1-PI), antibodies to S100B and myelin basic protein (MBP) in schizophrenia. Clinical symptoms were assessed on three scales: Positive and Negative Syndrome Scale, The Bush – Francis Catatonia Rating Scale and Frontal Assessment Battery. All SNPs were typed using predesigned TaqMan SNP genotyping assays. The biomarkers related to the immune system were routinely tested using ELISA kits. The association with schizophrenia was found for DRD3 rs6280 (p = 0.05) and HTR2A rs7322347 (p = 0.0013). We found differences between groups by parameters of LE and a1-PI and LE/a1-PI (p &lt; 0.001). And IL-6 was evaluated in the schizophrenia group (p &lt; 0.001). We showed that patients with the TT allele (BDNF rs6265) had more severe impairments in frontal lobe function. a1-PI can serve as a marker for assessing the severity of frontal lobe damage in patients with frontal dementia. We found some biological parameters reflecting the severity of frontal dysfunction in schizophrenia.

scholarly journals NE-Motion: Visual Analysis of Stroke Patients Using Motion Sensor Networks

Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4482
Author(s):  
Rodrigo Colnago Contreras ◽  
Avinash Parnandi ◽  
Bruno Gomes Coelho ◽  
Claudio Silva ◽  
Heidi Schambra ◽  
...  
Keyword(s):  
Visual Analysis ◽  
Treatment Strategies ◽  
Motion Capture Data ◽  
Motion Sensors ◽  
Healthy Individuals ◽  
Stroke Patients ◽  
Close Collaboration ◽  
Domain Experts ◽  
Bedside Test ◽  
Detailed Assessment

A large number of stroke survivors suffer from a significant decrease in upper extremity (UE) function, requiring rehabilitation therapy to boost recovery of UE motion. Assessing the efficacy of treatment strategies is a challenging problem in this context, and is typically accomplished by observing the performance of patients during their execution of daily activities. A more detailed assessment of UE impairment can be undertaken with a clinical bedside test, the UE Fugl–Meyer Assessment, but it fails to examine compensatory movements of functioning body segments that are used to bypass impairment. In this work, we use a graph learning method to build a visualization tool tailored to support the analysis of stroke patients. Called NE-Motion, or Network Environment for Motion Capture Data Analysis, the proposed analytic tool handles a set of time series captured by motion sensors worn by patients so as to enable visual analytic resources to identify abnormalities in movement patterns. Developed in close collaboration with domain experts, NE-Motion is capable of uncovering important phenomena, such as compensation while revealing differences between stroke patients and healthy individuals. The effectiveness of NE-Motion is shown in two case studies designed to analyze particular patients and to compare groups of subjects.

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