Relationship between plasma levels of leukotriene E4 and arterial partial pressure of carbon dioxide in asthmatic patients

Introduction: Despite several advantages over endotracheal tube (ETT), laryngeal mask airway (LMA), which is used in emergencies under difficult airway maintenance conditions, is rarely utilized in prolonged surgery. We compared the variables representing intraoperative gas exchange with second-generation LMA and ETT during prolonged laparoscopic abdominal surgery. Methods: Prolonged surgery was defined as a surgery lasting more than 2 h. In total, 394 patients who underwent laparoscopic liver resection via either second-generation LMA or ETT were retrospectively analysed. Parameters including end-tidal pressure of carbon dioxide (ETCO2), tidal volume (TV), respiratory rate (RR), peak inspiratory pressure (PIP), arterial partial pressure of carbon dioxide (PaCO2), pH, and ratio of arterial partial pressure of oxygen to fractional inspired oxygen (PFR) during surgery were compared between the two groups. In addition, the incidence of postoperative pulmonary complications (PPC) including pulmonary aspiration was also compared. Results: The values of ETCO2, TV, RR and PIP during pneumoperitoneum were comparable between the two groups. Although PaCO2 at 2 h after induction was higher in patients with LMA (40.5 vs. 38.5 mmHg, p < 0.001), the pH and PFR values of the two groups were comparable. The incidence of PPC was not different. Conclusion: During prolonged laparoscopic abdominal surgery, the second-generation LMA facilitates adequate intraoperative gas exchange and represents an alternative to ETT.

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Targeting Arterial Partial Pressure of Carbon Dioxide in Acute Respiratory Distress Syndrome Patients using Extracorporeal Carbon Dioxide Removal

Artificial Organs ◽

10.1111/aor.14127 ◽

2021 ◽

Author(s):

John K. Leypoldt ◽

Jörg Kurz ◽

Jorge Echeverri ◽

Markus Storr ◽

Kai Harenski

Keyword(s):

Carbon Dioxide ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Partial Pressure ◽

Distress Syndrome ◽

Carbon Dioxide Removal ◽

Extracorporeal Carbon Dioxide Removal ◽

Arterial Partial Pressure

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EFFECTS OF CO2 PNEUMOPERITONEUM ON ARTERIAL PARTIAL PRESSURE OF CARBON DIOXIDE PH, END TIDAL CARBON DIOXIDE AND BICARBONATE IN PATIENTS DURING LAPAROSCOPIC CHOLECYSTECTOMY

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2016/534 ◽

2016 ◽

Vol 5 (38) ◽

pp. 2299-2302

Author(s):

Abdul Hakeem ◽

Asif Iqbal ◽

Mohammad Dawood ◽

Basharat Saleem ◽

Abdul Hameed

Keyword(s):

Carbon Dioxide ◽

Laparoscopic Cholecystectomy ◽

Partial Pressure ◽

Co2 Pneumoperitoneum ◽

Arterial Partial Pressure ◽

End Tidal Carbon Dioxide ◽

End Tidal

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Automated Detection of Gastric Luminal Partial Pressure of Carbon Dioxide during Cardiovascular Surgery Using the Tonocap

Anesthesiology ◽

10.1097/00000542-200001000-00012 ◽

2000 ◽

Vol 92 (1) ◽

pp. 38-38 ◽

Cited By ~ 64

Author(s):

Elliott Bennett-Guerrero ◽

Michael H. Panah ◽

Carol A. Bodian ◽

Blessy J. Methikalam ◽

John R. Alfarone ◽

...

Keyword(s):

Carbon Dioxide ◽

Partial Pressure ◽

Postoperative Complication ◽

Artery Bypass ◽

Bypass Graft ◽

Automated System ◽

Hospital Death ◽

Published Data ◽

Arterial Partial Pressure ◽

Hemodynamic Variables

Background A new automated system of air tonometry (Tonocap; Datex Ohmeda, Helsinki, Finland) allows for frequent (every 15 min) measurement of gastric luminal partial pressure of carbon dioxide. Its use has not been described in cardiac surgical patients. Methods One hundred patients undergoing coronary artery bypass graft or cardiac valve surgery were enrolled in a prospective cohort study. After anesthetic induction and insertion of a TRIP NGS Catheter (Datex Ohmeda), measurements of gastric luminal partial pressure of carbon dioxide were obtained using the Tonocap, and gastric mucosal pH (pHi) was calculated. The main outcome measure was postoperative complication, defined as either in-hospital death or prolonged postoperative hospitalization (> 14 days). Results Four patients (4%) died, all of multiple-system organ failure, one each on postoperative days 9, 26, 46, and 121. Postoperative complication occurred in 18 patients (18%), all of whom exhibited persistent dysfunction of at least one organ system. Perioperatively, an abnormal pHi (< 7.32) and gastric luminal minus arterial partial pressure of carbon dioxide gap (> 8 mmHg) occurred in 66% and 70% of patients, respectively. Predictors of postoperative complication included postoperative pHi (P = 0.001), gastric luminal partial pressure of carbon dioxide (P = 0.022), and gastric luminal minus arterial partial pressure of carbon dioxide gap (P = 0.013). In contrast, arterial base excess (P > 0.4) and routinely measured hemodynamic variables (e.g., heart rate, blood pressure) were either less predictive compared with Tonocap-derived variables or not predictive. Conclusions Despite a low mortality rate, patients undergoing cardiac surgery exhibited high incidences of prolonged hospitalization and postoperative morbidity. The Tonocap was easy to use, particularly compared with saline tonometry. Several Tonocap-derived variables were predictive of postoperative complications consistent with previously published data using saline tonometry.

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Changes in arterial partial pressure and end-expired pressure of carbon dioxide in prepubescent and adult bitches undergoing ovariohysterectomy by videolaparoscopy or conventional laparotomy

Ciência Rural ◽

10.1590/0103-8478cr20170769 ◽

2018 ◽

Vol 48 (10) ◽

Author(s):

Luciana Branquinho Queiroga ◽

Gabriela Marques Sessegolo ◽

Fabiane Reginatto dos Santos ◽

Letícia Mendes Fratini ◽

Verônica Santos Mombach ◽

...

Keyword(s):

Carbon Dioxide ◽

Partial Pressure ◽

Postoperative Period ◽

Base Excess ◽

Mild Hypertension ◽

Peak Inspiratory Pressure ◽

Arterial Partial Pressure ◽

Significant Difference ◽

The Difference ◽

Age Range

ABSTRACT: This paper aimed to determine arterial partial pressure of carbon dioxide (PaCO2), end-expired CO2 pressure (ETCO2), and the difference between arterial and end-expired CO2 pressure (Pa - ETCO2) in prepubescent and adult bitches undergoing videolaparoscopic or conventional ovariohyterectomy (OH). Forty bitches were randomly assigned to four groups: Conventional Adult (CA), Conventional Pediatric (CP), Videolaparoscopic Adult (VA) and Videolaparoscopic Pediatric (VP). Pulse rate (PR), respiratory rate (RR), systolic, mean, and diastolic arterial pressures (SAP, MAP, DAP), ETCO2, peak inspiratory pressure (PIP), pH, arterial partial pressure of oxygen (PaO2), PaCO2, base excess (BE) and HCO3 - were measured. Based on the PaCO2 and ETCO2 values, Pa-ETCO2 was determined. There was no significant difference in PaCO2 between the VA (42.5±5.2 to 53.7±5.2) and VP (48.4±5.4 to55.4±5.7) groups. During the postoperative period, all groups presented with hypertension. However, mild hypertension (SAP 150 to 159mmHg) was observed in the VP group as compared to severe hypertension (SAP>180mmHg) in the CA group, suggesting that both the age range and videolaparoscopic OH are associated with lower levels of hypertension during the postoperative period in dogs.

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