The Influence of Body Mass Index on Reproductive Outcomes in Patients with Polycystic Ovarian Syndrome Undergoing In-Vitro Fertilization

Background: The aim of this study is to assess the effect of body mass index (BMI) on outcomes of in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) among polycystic ovarian syndrome (PCOS) and non-PCOS patients. Methods: This was a retrospective cohort study that was performed in the Second Hospital of Hebei Medical University. Patients who were under 35 years old were included in the study and were divided into four groups based on their BMI. The number of retrieved oocytes, implantation rate, clinical pregnancy rate, miscarriage rate and live births among PCOS and non-PCOS patients were compared between different BMIs. Results: IVF/ICSI pregnancies in obese PCOS women had a considerably higher risk of miscarriage and low rate of clinical pregnancy than in non-obese PCOS pregnancies. However, in non-PCOS patient, obesity significantly elevated miscarriage rate but did not affect clinical pregnancy rate. Conclusion: Obesity in PCOS patients led to poor outcomes of IVF/ICSI.

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Comprehensive analysis of body mass index effects on in vitro fertilization outcomes

10.26226/morressier.573c1512d462b80296c98821 ◽

2016 ◽

Author(s):

Laura Privitera

Keyword(s):

Body Mass Index ◽

In Vitro Fertilization ◽

Body Mass ◽

Comprehensive Analysis ◽

Vitro Fertilization

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Body Mass Index, Follicle-Stimulating Hormone and their Predictive Value in vitro Fertilization

Revista de Chimie ◽

10.37358/rc.18.7.6428 ◽

2018 ◽

Vol 69 (7) ◽

pp. 1842-1845

Author(s):

Lavinia Stelea ◽

Izabella Petre ◽

Marius Craina ◽

Brigitha Vlaicu ◽

Alina Sisu ◽

...

Keyword(s):

Body Mass Index ◽

Risk Factor ◽

In Vitro Fertilization ◽

Body Mass ◽

Predictive Value ◽

Follicle Stimulating Hormone ◽

Vitro Fertilization ◽

Weight Problems ◽

Fertility Disorder

The aim of this study was to determine if body mass can be considered a risk factor for infertility, and if we can find any correlations between the age values and the FSH and estradiol values, and between the BMI values and the FSH and estradiol values. Our whole sample contains 100 patients splinted in two groups (pregnant patients N1=57 subjects, 57%, and not � pregnant patients N1=43 subjects,43%). In the first part we conducted our analysis on the whole group and after that we focused the analysis on the two groups and we made some comparisons between the groups. We obtained a medium, extremely significant correlation in all scenarios between the age and the FSH values. This is the best association from all the cases which we tested. In all twelve cases we have a positive correlation (r ] 0). As well, we obtained that a BMI value higher than 25can be considered a risk factor for obtaining a pregnancy (p[0.05, RR ] 1, OR]1) . Our study shows that women who have weight problems have much less chances of conceiving a baby, even if they ovulate normally. The risk of infertility increases proportionally to the extra pounds. Irregular ovulation in women is the most common fertility disorder due to obesity disease.

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