Use of the total motile sperm count to predict total fertilization failure in in vitro fertilization

2002 ◽  
Vol 78 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Sjoerd Repping ◽  
Janne-Meije van Weert ◽  
Ben W.J Mol ◽  
Jan W.A de Vries ◽  
Fulco van der Veen
Keyword(s):  
In Vitro Fertilization ◽  
Sperm Count ◽  
Fertilization Failure ◽  
Motile Sperm ◽  
Vitro Fertilization ◽  
Total Fertilization Failure ◽  
Total Motile Sperm Count

Use of the total motile sperm count to predict pregnancy outcomes in in vitro fertilization

2013 ◽  
Vol 100 (3) ◽  
pp. S448
Author(s):  
Y.Y. Kim ◽  
K.H. Lee ◽  
I.H. Park ◽  
H.G. Sun ◽  
S.G. Kim ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Outcomes ◽  
Sperm Count ◽  
Motile Sperm ◽  
Vitro Fertilization ◽  
Total Motile Sperm Count

scholarly journals Post-wash total motile sperm count a useful predictor in the decision to perform IVF/ICSI in patients with non-male factor infertility

2020 ◽  
Vol 3 (2) ◽  
pp. 99-106
Author(s):  
Sara Mahmood Qureshi ◽  
Salma Kafeel ◽  
Riffat Bibi ◽  
Jawad Mohmand
Keyword(s):  
Sperm Quality ◽  
Sperm Count ◽  
Adverse Outcomes ◽  
Male Factor Infertility ◽  
Motile Sperm ◽  
Operating Characteristics ◽  
Male Factor ◽  
Vitro Fertilization ◽  
Total Motile Sperm Count

Introduction: The unrestricted use of intracytoplasmic sperm injection (ICSI) for non-male factor infertility is associated with adverse outcomes. Post-wash total motile sperm count (PW-TMSC) offers prognostic value to assess sperm quality and aid in the decision to perform in vitro fertilization (IVF) or ICSI. Objectives: The aim of this study was to identify the effect of PW-TMSC on fertilization rates in patients undergoing IVF cycles exclusively with non-male factor infertility. It also aimed to identify whether unnecessary ICSI could be avoided in such cases, thus maximizing optimal outcomes. Materials & Methods: We retrospectively analyzed age, semen volume, prewash TMSC, and PW-TMSC in 68 conventional IVF cycles of infertile couples with non-male factor infertility. Clinical characteristics including female age, number of follicles, level of estradiol on trigger day, mature cumulus-oocyte complexes (COCs) collected, were also included. Results: Incidence of <30% fertilization was significantly higher in the 4-<10 Million group compared with the ≥20 Million post-wash TMSC group (P<0.001). Furthermore, Receiver operating characteristics (ROC) analysis revealed post-wash TMSC as a significant predictor (P<0.05) of total failed fertilization (TFF) and of ≥30% fertilization (P<0.05) with area under curve (AUC) of 0. 79 and 0.77, respectively, with a deemed cutoff of 10.89 Million. Conclusion: Post-wash TMSC is a good predictor of fertilization; it can help in avoiding potentially low or even total fertilization failure (TFF). A cut-off point of 10.89 Million or less should warrant the use of ICSI.

scholarly journals Comparison of short and long co-incubation time of gametes for in vitro fertilization

2019 ◽  
Vol 8 (11) ◽  
pp. 4366
Author(s):  
Pallop Pongsuthirak
Keyword(s):  
In Vitro Fertilization ◽  
Incubation Time ◽  
Pregnancy Outcomes ◽  
Fertilization Failure ◽  
Vitro Fertilization ◽  
Group I ◽  
Significant Difference ◽  
Total Fertilization Failure ◽  
Rescue Icsi

Background: The short and long co-incubation time of gametes for in vitro fertilization are still debatable issues. This study aims to investigate the effects of short and long co-incubation time of gametes on fertilization, polyspermy, embryonic developmental potential, and clinical outcomes.Methods: Sixty-five patients undergoing IVF treatment were invited to participate in the study between May 2017 and March 2019. Ovarian hyperstimulation was prescribed and oocytes were obtained by trans-vaginal aspiration under ultrasound guidance. Sibling oocytes were randomly allocated to short co-incubation for 4 hours (Group I) in 352 oocytes and long co-incubation for 16-18 hours in 363 oocytes (Group II). Rescue ICSI was carried out if total fertilization failure was documented. Fertilization, embryonic development, and pregnancy outcomes were determined.Results: No significant differences between short and long co-incubation were found in fertilization, polyspermy, cleavage, blastocyst, implantation, clinical pregnancy, and live birth rates.Conclusions: The present study showed that short co-incubation of gametes had no significant difference in fertilization, polyspermy, embryo development, and pregnancy outcomes when compared to long co-incubation. The short co-incubation with early cumulus cell removal and rescue ICSI may have the potential to help a couple who had total fertilization failure.

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