Changes induced by metformin and high protein diet on lipoproteins and body mass index in patients with polycystic ovarian syndrome

2003 ◽  
Vol 80 ◽  
pp. 274
Author(s):  
T. McElroy ◽  
S. Vijayakumar ◽  
M.B. Kavanagh ◽  
J. Liu ◽  
F. Arredondo ◽  
...  
2015 ◽  
Vol 148 (4) ◽  
pp. S-671-S-672
Author(s):  
Deepinder Goyal ◽  
Lixin Wang ◽  
Gigi Kwok ◽  
Jihane Benhammou ◽  
Gordon V. Ohning ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1384
Author(s):  
Bruna M. Giglio ◽  
Valeska I. R. Duarte ◽  
Ana Flávia Galvão ◽  
Ana Clara B. Marini ◽  
Raquel M. Schincaglia ◽  
...  

The aim was to evaluate whether the ingestion of a high protein diet containing dairy protein is associated with anthropometric indicators of adiposity and blood glucose. Methods: A cross-sectional study was conducted with volunteers of 20–89 years of age who performed leisure physical activity. We assessed dietary intake, body mass index (BMI), waist circumference (WC), triceps skinfold thickness (TSFT), random blood glucose as well as sociodemographic and behavioral variables. Results: A total of 418 individuals were evaluated. The consumption of a high-protein diet (1.80 ± 0.49 g/kg/day) was found in 37.8% of individuals, which showed lower BMI, WC, TSFT and blood glucose concentrations compared to those with a low-protein diet (0.56 ± 0.18 g/kg/day). Dairy products consumption was inversely associated with BMI when adjusted for sex and age (odds ratio (OR): 0.79, 95% confidence interval (CI): 0.68–0.93, p = 0.004) and by sex, age, fiber and energy (OR: 0.79; 95% CI: 0.67–0.92; p = 0.004), and with blood glucose when adjusted for sex and age (OR: 0.86; 95% CI: 0.74–0.99; p = 0.042). Cheese consumption was inversely associated with blood glucose when adjusted for sex and age (OR: 0.73, 95% CI: 0.55–0.96, p = 0.023) and by sex, age, calories and fibers (OR: 0.74, 95% CI: 0.56–0.98, p = 0.036). Two portions of cheeses/day reduced the risk of having high blood glucose levels by approximately 80%. Conclusion: A high-protein diet containing dairy food, in particular two servings of cheese, was associated with low BMI and random glucose concentration.


Endocrine ◽  
2018 ◽  
Vol 61 (1) ◽  
pp. 144-148 ◽  
Author(s):  
Joana Simões-Pereira ◽  
Joaquim Nunes ◽  
Ana Aguiar ◽  
Sandra Sousa ◽  
Cátia Rodrigues ◽  
...  

2016 ◽  
Vol 48 ◽  
pp. 443
Author(s):  
John J. Sepowitz ◽  
Holly L. McClung ◽  
Claire E. Berryman ◽  
Nicholes J. Armstrong ◽  
Arny A. Ferrando ◽  
...  

2007 ◽  
Vol 92 (4) ◽  
pp. 1347-1352 ◽  
Author(s):  
Serene S. Srouji ◽  
Yanira L. Pagán ◽  
Fernando D’Amato ◽  
Amsalu Dabela ◽  
Yarisie Jimenez ◽  
...  

Metabolism ◽  
1994 ◽  
Vol 43 (12) ◽  
pp. 1481-1487 ◽  
Author(s):  
P.M. Piatti ◽  
L.D. Monti ◽  
Fulvio Magni ◽  
Isabella Fermo ◽  
L. Baruffaldi ◽  
...  

Author(s):  
Shivani Jalota ◽  
Jatinder Singh ◽  
Ravi Saini

Background: Polycystic ovarian syndrome is a common endocrine disorder seen in reproductive age group. Hirsutism, oligomennorhea and infertility being the most common chief complaint. Oral contraceptives have shown their efficacy in hirsute females. Metformin, an insulin sensitizer, have also shown some beneficial effects in improving metabolic abnormalities. Aim of this study is to compare the efficacy of metformin alone and metformin with fixed dose combination of cyproterone acetate and ethinyl estradiol in hirsute women with PCOS.Methods: 60 females of PCOS with chief complaint of hirsutism were enrolled. Patients were randomized to either metformin and Diane -35 (35 microgram ethinyl estradiol plus 2mg cyproterone acetate) or metformin and placebo for 9 months. Ferriman Gallwey score and body mass index was calculated at baseline, 3months, 6months and 9 months. FSH/LH/Prolactin/Testosterone/Fasting glucose and Fasting insulin levels were measured at the baseline and at the end of treatment.Results: Majority of females enrolled in the study were in third decade of life. Metformin and Diane- 35 showed higher reduction in Ferriman Gallwey score but Body mass index was reduced in both the groups. There was no significant difference seen between the groups with respect to biochemical profile.Conclusions: This data show that a combination of metformin and contraceptive pill may be more effective in treating hirsutism than metformin alone. Beneficial effects of therapy were seen in relation to BMI as well. Hence, combination therapy is better therapeutic option for treating hirsutism in PCOS. 


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