The rat fundus, a valid model to characterize agents acting at human 5-HT29 receptors

2001 ◽  
Vol 120 (5) ◽  
pp. A208-A208
Author(s):  
E WEBER ◽  
M BERNHARD ◽  
H PFANNKUCHE
Keyword(s):  
SAGE Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 215824402110275
Author(s):  
Farrah Dina Yusop ◽  
Akhmad Habibi ◽  
Rafiza Abdul Razak

The goals of the research were to inform whether the theory of planned behavior (TPB) is a valid model to explain Indonesian preservice teachers’ (PSTs) use of information and communication technology (UICT) during teaching practices, to report best factor affecting PSTs’ UICT during teaching practices, and to elaborate differences regarding UICT during teaching practices in terms of demographic information, gender, major, university, and information and communication technology (ICT)-based courses. The sample of this study was 1,133 PSTs from three Indonesian universities who completed a 24-item printed questionnaire of four constructs: behavioral beliefs (BB), normative beliefs (NB), control beliefs (CB), and UICT. Using partial least square–structural equation modeling (PLS-SEM), the results informed that the TPB is a valid model to help explain Indonesian PSTs’ UICT during teaching practices. All constructs (BB, NB, and CB) significantly predict UICT during teaching practices where NB is reported to be the strongest predictor (β = .354). There are no significant differences in terms of genders and ICT-based courses; however, significant differences are indicated in terms of majors and universities.


2003 ◽  
Vol 185 (5) ◽  
pp. 1745-1748 ◽  
Author(s):  
Jan Rybniker ◽  
Martina Wolke ◽  
Christiane Haefs ◽  
Georg Plum

ABSTRACT Mycobacterium marinum is a close relative of the obligate human pathogen Mycobacterium tuberculosis. As with M. tuberculosis, M. marinum causes intracellular infection of poikilothermic vertebrates and skin infection in humans. It is considered a valid model organism for the study of intracellular pathogenesis of mycobacteria. Low transformation efficiencies for this species have precluded approaches using mutant libraries in pathogenesis studies. We have adapted the conditionally replicating mycobacteriophage phAE94, originally developed as a transposon mutagenesis tool for M. tuberculosis, to meet the specific requirements of M. marinum. Conditions permissive for phage replication in M. tuberculosis facilitated highly efficient transposon delivery in M. marinum. Using this technique we succeeded in generating a representative mutant library of this species, and we conclude that TM4-derived mycobacteriophages are temperature-independent suicide vectors for M. marinum.


2010 ◽  
Vol 65 (7) ◽  
pp. 430-431 ◽  
Author(s):  
Rudi Campo ◽  
Christoph Reising ◽  
Yves Van Belle ◽  
Joseph Nassif ◽  
Peter OʼDonovan ◽  
...  

PEDIATRICS ◽  
1983 ◽  
Vol 71 (2) ◽  
pp. 300-300
Author(s):  
HOWARD EIGEN

To the Editor.— The controversy over which method provides the best relief of central airway obstruction has been marked by the publishing of a myriad of "Special Comments," editorials, and statements, and a dearth of scientific studies. The interesting study by Day and co-workers1 brings a new point of view to this problem by looking at ballistic forces. The question remains as to whether the model of a ball rolling free in a rigid tube is a valid model for soft food lodged in a distensible airway.


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