M1212 Celiac Disease Serology with Very High Accuracy May Obviate Diagnostic Intestinal Biopsy in Different Clinical Scenarios

2008 ◽  
Vol 134 (4) ◽  
pp. A-362
Author(s):  
Emilia Sugai ◽  
María Laura Moreno ◽  
Hui Jer Hwang ◽  
Adriana Crivelli ◽  
Fabio Nachman ◽  
...  
Keyword(s):  
Celiac Disease ◽  
High Accuracy ◽  
Intestinal Biopsy ◽  
Clinical Scenarios ◽  
Very High

scholarly journals Stellar magnetic imaging from spectropolarimetric data

1996 ◽  
Vol 176 ◽  
pp. 53-60 ◽  
Author(s):  
J.-F. Donati
Keyword(s):  
Small Amplitude ◽  
High Accuracy ◽  
Spectral Lines ◽  
New Method ◽  
Doppler Imaging ◽  
Magnetic Imaging ◽  
Active Stars ◽  
Surface Fields ◽  
Very High

In this paper, I will review the capabilities of magnetic imaging (also called Zeeman-Doppler imaging) to reconstruct spot distributions of surface fields from sets of rotationnally modulated Zeeman signatures in circularly polarised spectral lines. I will then outline a new method to measure small amplitude magnetic signals (typically 0.1% for cool active stars) with very high accuracy. Finally, I will present and comment new magnetic images reconstructed from data collected in 1993 December at the Anglo-Australian Telescope (AAT).

scholarly journals Celiac disease: Understandings in diagnostic, nutritional, and medicinal aspects

2021 ◽  
Vol 35 ◽  
pp. 205873842110087
Author(s):  
Taoufik Ben Houmich ◽  
Brahim Admou
Keyword(s):  
Celiac Disease ◽  
Villous Atrophy ◽  
Current Trend ◽  
Diagnostic Delay ◽  
General Medicine ◽  
Iga Deficiency ◽  
Health Concern ◽  
Intestinal Biopsy ◽  
Antibody Testing ◽  
Main Challenge

Celiac disease (CD) is characterized by clinical polymorphism, with classic, asymptomatic or oligosymptomatic, and extra-intestinal forms, which may lead to diagnostic delay and exposure to serious complications. CD is a multidisciplinary health concern involving general medicine, pediatric, and adult gastroenterology, among other disciplines. Immunology and pathology laboratories have a fundamental role in diagnosing and monitoring CD. The diagnosis consists of serological testing based on IgA anti-transglutaminase (TG2) antibodies combined with IgA quantification to rule out IgA deficiency, a potential misleading factor of CD diagnosis. Positive TG2 serology should be corroborated by anti-endomysium antibody testing before considering an intestinal biopsy. Owing to multiple differential diagnoses, celiac disease cannot be confirmed based on serological positivity alone, nor on isolated villous atrophy. In children with classical signs or even when asymptomatic, with high levels of CD-linked markers and positive HLA DQ2 and/or DQ8 molecules, the current trend is to confirm the diagnosis on basis of the non-systematic use of the biopsy, which remains obligatory in adults. The main challenge in managing CD is the implementation and compliance with a gluten-free diet (GFD). This explains the key role of the dietitian and the active participation of patients and their families throughout the disease-management process. The presence of the gluten in several forms of medicine requires the sensitization of physicians when prescribing, and particularly when dispensing gluten-containing formulations by pharmacists. This underlines the importance of the contribution of the pharmacist in the care of patients with CD within the framework of close collaboration with physicians and nutritionists.

Hole Accuracy during Deep Hole Drilling for Hydraulic Cylinder Application

2014 ◽  
Vol 984-985 ◽  
pp. 67-72 ◽  
Author(s):  
R. Clifford Benjamin Raj ◽  
B. Anand Ronald ◽  
A. Velayudham ◽  
Prasmit Kumar Nayak
Keyword(s):  
Feed Rate ◽  
Drill Hole ◽  
Hydraulic Cylinder ◽  
High Accuracy ◽  
Diameter Ratio ◽  
Hole Drilling ◽  
Deep Hole ◽  
Deep Hole Drilling ◽  
Very High ◽  
Continuous Chip

Deep-hole drilling is a process in which the hole length will be very high when compared to diameter of the drill hole (i.e. length to diameter ratio will be greater than 5). Drilling a deep hole with very high accuracy is difficult process. The current project is about the production of deep hole with the aim to produce a chip which is not a continuous chip and also not a powdery chip. These conditions can be attained by varying the spindle speed and the tool feed rate.

Cost Effective Swath Bathymetry

2001 ◽  
Vol 35 (4) ◽  
pp. 33-45 ◽  
Author(s):  
Peter Hogarth
Keyword(s):  
Processing Time ◽  
Cost Effective ◽  
High Accuracy ◽  
High Coverage ◽  
Swath Bathymetry ◽  
World Survey ◽  
Set Up ◽  
Very High ◽  
Harbor Area ◽  
Wide Swath

Between 23rd and 25th July 2001 GeoSwath, a high specification shallow water wide swath bathymetry system, was used to survey the entire Portsmouth NH Harbor area. This paper deals with the results of this survey, illustrating the potential for significant reductions in the high costs, which have prevented widespread proliferation of Swath Bathymetry systems to date. Data, including a complete DTM gridded to 1 m resolution, will be presented and discussed in detail. These results show that the system is very easy to set up and use, requires greatly reduced boat and processing time, whilst offering high accuracy and very high coverage and resolution when used in a real-world survey of a dynamic harbor environment.

Nutritional Management of Celiac Disease

2018 ◽  
Author(s):  
Ciarán P Kelly ◽  
Satya Kurada ◽  
Mariana Urquiaga
Keyword(s):  
Immune Response ◽  
Celiac Disease ◽  
Tight Junction ◽  
Villous Atrophy ◽  
Gastrointestinal Symptoms ◽  
Gluten Free Diet ◽  
Intestinal Biopsy ◽  
Nutritional Management ◽  
Gluten Free ◽  
Antigliadin Antibodies

Celiac disease (CD) is an autoimmune disorder characterized by an immune response to gluten peptides in wheat, barley, and rye. The diagnosis of celiac disease is confirmed by three important characteristics: consistent symptoms, positive celiac-specific serology, and small intestinal biopsy findings of inflammation, crypt hyperplasia, and villous atrophy. CD may present with overt gastrointestinal symptoms, including diarrhea (or constipation), weight loss, and abdominal bloating and discomfort, or covertly with micronutrient deficiencies such as iron deficiency with anemia. A gluten-free diet (GFD) remains the mainstay of treatment. The aim of this review is to highlight the pathogenesis of CD, concepts and challenges associated with a GFD, and nutritional management of CD applicable in clinical practice to internists, gastroenterologists, and dietitians. Patients should be referred to an expert celiac dietitian for education on adherence to a GFD to address gluten contamination in the diet, the psychosocial implications of following a GFD, and macro- and micronutrient disequilibria arising from celiac disease and the GFD. Several novel therapeutics are on the horizon in various stages of development, including glutenases, antigliadin antibodies, tight junction regulators, modulation of the immune response to gliadin, and efforts to engineer less toxic gluten-containing foodstuffs. This review contains 3 figures, 5 tables, and 61 references. Key words: celiac disease, genetic engineering, food engineering, gluten, glutenases, gluten-free diet, oats, IgY, nutrition, tight junction regulators, wheat

A high accuracy linear rate meter

1975 ◽  
Vol 39 (2) ◽  
pp. 327-330
Author(s):  
C. R. Wyss
Keyword(s):  
Circuit Design ◽  
Digital Circuits ◽  
Analog Computer ◽  
High Accuracy ◽  
Digital Display ◽  
Instantaneous Rate ◽  
Linear Rate ◽  
Very High ◽  
Design Techniques

By implementing analog computer techniques using digital circuits, an instantaneous rate meter was built with approximately 100 times the accuracy of commercially available rate meters. The circuit is accurate to within +/- 0.2 events/min over a range of rates of 0.2–900 epm. Modifications can be made to provide a digital display of rate. The circuit design techniques used in developing the rate meter may be used to generate a wide variety of functions of time with very high accuracy.

Discrete differential operators for periodic and two-periodic time functions

2019 ◽  
Vol 38 (1) ◽  
pp. 325-347 ◽  
Author(s):  
Tadeusz Sobczyk ◽  
Michał Radzik ◽  
Natalia Radwan-Pragłowska
Keyword(s):  
Differential Operators ◽  
High Accuracy ◽  
Large Set ◽  
Periodic Functions ◽  
Content Type ◽  
Second Derivatives ◽  
Non Linear ◽  
Discrete Operators ◽  
Linear Differential ◽  
Very High

Purpose To identify the properties of novel discrete differential operators of the first- and the second-order for periodic and two-periodic time functions. Design/methodology/approach The development of relations between the values of first and second derivatives of periodic and two-periodic functions, as well as the values of the functions themselves for a set of time instants. Numerical tests of discrete operators for selected periodic and two-periodic functions. Findings Novel discrete differential operators for periodic and two-periodic time functions determining their first and the second derivatives at very high accuracy basing on relatively low number of points per highest harmonic. Research limitations/implications Reduce the complexity of creation difference equations for ordinary non-linear differential equations used to find periodic or two-periodic solutions, when they exist. Practical implications Application to steady-state analysis of non-linear dynamic systems for solutions predicted as periodic or two-periodic in time. Originality/value Identify novel discrete differential operators for periodic and two-periodic time functions engaging a large set of time instants that determine the first and second derivatives with very high accuracy.

Successes and Predictions of A Pseudopotential Approach in Anion-Mixed Nitrides

2001 ◽  
Vol 692 ◽  
Author(s):  
L. Bellaiche ◽  
A. Al-Yacoub ◽  
N. A. Modine ◽  
E. D. Jones
Keyword(s):  
Solid Solutions ◽  
Complex Anion ◽  
High Accuracy ◽  
Nitride Alloys ◽  
Pseudopotential Approach ◽  
Strain Dependent ◽  
Very High

AbstractThe construction and the parameters of a new-strain dependent empirical pseudopotentials method are described and provided, respectively. This method is shown to reproduce with a very high accuracy some observed unusual properties in various complex anion-mixed nitride alloys. This method is also used to predict and understand anomalous effects that remain to be experimentally discovered in Ga1−yInyAs1−xNx quaternaries and GaAs0.5−xP0.5−xN2x solid solutions.

New CAD for Rapid Prototyping

1996 ◽  
Author(s):  
Shuichi Fukuda ◽  
Daisuke Suzuki
Keyword(s):  
Rapid Prototyping ◽  
High Accuracy ◽  
Layer By Layer ◽  
Measurement Device ◽  
Detailed Design ◽  
Cad Systems ◽  
Cad System ◽  
Design And Manufacturing ◽  
Cad Tool ◽  
Very High

Abstract We developed a new CAD tool with special attention paid to rapid prototyping. Most of the present 3-D CAD systems treat geometry with very high accuracy but it is not easy to define or modify geometry as we do in the earlier stages of design. The present CAD systems, we believe, are more oritented toward the detailed design and manufacturing of the final product. As rapid prototyping itself is intended for the earlier stages of design, such a CAD system that permitts more easy or rough definition and modification of geometry is really desired. Most of the rapid prototyping systems generate 3-D geometry by piling up the 2-D sections layer by layer. So, if we develop such a layer-based CAD system, then we could more easily tranfer CAD data to the prototyping system. Such an idea was very old, but the traditional ones cannot manipulate geometry with much ease. What we aimed here is to develop a system that a designer can manipuate geometry as freely as he or she wishes. Thus, our system serves as a preprocessor to the present 3-D CAD systems. We are developing another system which permits to generate 3-D geometry as freely as if we are drawing it using a pen, based on the technology of 3-D measurement device. Couled with this system, the system we are proposing here is expected to tranfer such a 3-D geometry data very rapidly and easily to the prototyping equipment and also can interactively modify thus defined geometry data.

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