Recognition of Mucosal Surface Patterns With Narrow Band Imaging Among GI Fellows: Pre and Post-Test Analysis

In celiac disease (CD), the intestinal lesions can be patchy and partial villous atrophy may elude detection at standard endoscopy (SE). Narrow Band Imaging (NBI) system in combination with a magnifying endoscope (ME) is a simple tool able to obtain targeted biopsy specimens. The aim of the study was to assess the correlation between NBI-ME and histology in CD diagnosis and to compare diagnostic accuracy between NBI-ME and SE in detecting villous abnormalities in CD. Forty-four consecutive patients with suspected CD undergoing upper gastrointestinal endoscopy have been prospectively evaluated. Utilizing both SE and NBI-ME, observed surface patterns were compared with histological results obtained from biopsy specimens using the k-Cohen agreement coefficient. NBI-ME identified partial villous atrophy in 12 patients in whom SE was normal, with sensitivity, specificity, and accuracy of 100%, 92.6%, and 95%, respectively. The overall agreement between NBI-ME and histology was significantly higher when compared with SE and histology (kappa score: 0.90 versus 0.46; P=0.001) in diagnosing CD. NBI-ME could help identify partial mucosal atrophy in the routine endoscopic practice, potentially reducing the need for blind biopsies. NBI-ME was superior to SE and can reliably predict in vivo the villous changes of CD.

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Use of narrow-band imaging in detection of nasopharyngeal carcinoma

The Journal of Laryngology & Otology ◽

10.1017/s0022215112002940 ◽

2013 ◽

Vol 127 (2) ◽

pp. 163-169 ◽

Cited By ~ 9

Author(s):

J F Thong ◽

D Loke ◽

R Karumathil Sivasankarannair ◽

P Mok

Keyword(s):

Nasopharyngeal Carcinoma ◽

Narrow Band ◽

Narrow Band Imaging ◽

Papillary Adenocarcinoma ◽

Nasopharyngeal Mass ◽

Surface Patterns ◽

Brown Centre ◽

Epstein Barr ◽

Characteristic Features ◽

Adenoidal Tissue

AbstractAim:To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.Method:Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein–Barr viral serology was tested for all patients.Results:Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each ‘follicle’ comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (n = 7), and/or (2) ‘reverse’, haphazard follicular pattern comprising a dark brown centre and pale periphery (n = 3).Conclusion:Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.

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TXI (Texture and Color Enhancement Imaging) for Serrated Colorectal Lesions

Journal of Clinical Medicine ◽

10.3390/jcm11010119 ◽

2021 ◽

Vol 11 (1) ◽

pp. 119

Author(s):

Toshihiro Nishizawa ◽

Osamu Toyoshima ◽

Shuntaro Yoshida ◽

Chie Uekura ◽

Ken Kurokawa ◽

...

Keyword(s):

Narrow Band ◽

Narrow Band Imaging ◽

Colorectal Polyps ◽

Serrated Polyps ◽

Serrated Lesions ◽

Surface Patterns ◽

Visibility Score ◽

Color Enhancement ◽

Image Enhancing ◽

White Light Imaging

Background and aim: Olympus Corporation released the texture and color enhancement imaging (TXI) technology as a novel image-enhancing endoscopic technique. We investigated the effectiveness of TXI in the imaging of serrated colorectal polyps, including sessile serrated lesions (SSLs). Methods: Serrated colorectal polyps were observed using white light imaging (WLI), TXI, narrow-band imaging (NBI), and chromoendoscopy with and without magnification. Serrated polyps were histologically confirmed. TXI was compared with WLI, NBI, and chromoendoscopy for the visibility of the lesions without magnification and for that of the vessel and surface patterns with magnification. Three expert endoscopists evaluated the visibility scores, which were classified from 1 to 4. Results: Twenty-nine consecutive serrated polyps were evaluated. In the visibility score without magnification, TXI was significantly superior to WLI but inferior to chromoendoscopy in the imaging of serrated polyps and the sub-analysis of SSLs. In the visibility score for vessel patterns with magnification, TXI was significantly superior to WLI and chromoendoscopy in the imaging of serrated polyps and the sub-analysis of SSLs. In the visibility score for surface patterns with magnification, TXI was significantly superior to WLI but inferior to NBI in serrated polyps and in the sub-analysis of SSLs and hyperplastic polyps. Conclusions: TXI provided higher visibility than did WLI for serrated, colorectal polyps, including SSLs.

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Faculty Opinions recommendation of Narrow-band imaging colonoscopy--a pilot feasibility study for the detection of polyps and correlation of surface patterns with polyp histologic diagnosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104551.560602 ◽

2008 ◽

Author(s):

Peter Katelaris

Keyword(s):

Feasibility Study ◽

Narrow Band ◽

Narrow Band Imaging ◽

Histologic Diagnosis ◽

Surface Patterns ◽

Pilot Feasibility Study

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Magnifying narrow-band imaging of surface patterns for diagnosing colorectal cancer

Oncology Reports ◽

10.3892/or.2013.2471 ◽

2013 ◽

Vol 30 (1) ◽

pp. 350-356 ◽

Cited By ~ 4

Author(s):

MASASHI MISAWA ◽

SHIN-EI KUDO ◽

YOSHIKI WADA ◽

HIROKI NAKAMURA ◽

NAOYA TOYOSHIMA ◽

...

Keyword(s):

Colorectal Cancer ◽

Narrow Band ◽

Narrow Band Imaging ◽

Surface Patterns

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Additive Effects of Evaluating Micro-Surface and Microvascular Patterns Using Magnifying Endoscopy with Narrow-Band Imaging for Gastric Cancer

10.21203/rs.3.rs-882467/v1 ◽

2021 ◽

Author(s):

Yusuke Horiuchi ◽

Toshiaki Hirasawa ◽

Naoki Ishizuka ◽

Junki Tokura ◽

Mitsuaki Ishioka ◽

...

Keyword(s):

Gastric Cancer ◽

Diagnostic Accuracy ◽

Diagnostic Performance ◽

Evaluation Method ◽

Narrow Band ◽

Narrow Band Imaging ◽

Magnifying Endoscopy ◽

Additive Effects ◽

Surface Patterns ◽

Microvascular Pattern

Abstract No studies have compared the performance of microvascular and micro-surface patterns alone with their combination in magnifying endoscopy with narrow-band imaging for diagnosing gastric cancer. This study aimed to clarify the difference in diagnostic performance between these methods. Thirty-three participating endoscopists underwent specialized training in magnifying endoscopy evaluated microvascular and micro-surface patterns for images of 106 cancerous and 106 non-cancerous cases. If classified as “irregular”, the lesion was diagnosed as cancerous. To evaluate diagnostic performance, we compared the diagnostic accuracy, sensitivity, and specificity among the methods. Performance-related items did not significantly differ between the microvascular and micro-surface patterns. However, the diagnostic accuracy and sensitivity were significantly higher when using the combination of these methods than when using the microvascular pattern alone (percentage [95% confidence interval]: 82.1% [76.4–86.7] vs. 76.4% [70.3–81.6], P = 0.0005; and 69.8% [60.5–77.8] vs. 63.2% [53.7–71.8], P = 0.0082, respectively). The additive effects on diagnostic accuracy and sensitivity were 5.7% and 6.6%, respectively. The combination of micro-surface and microvascular patterns has superior diagnostic accuracy and sensitivity for diagnosing gastric cancer than the evaluation method using microvascular pattern alone. Our results may contribute to improving the diagnosis of gastric cancers.

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Multicenter prospective study on the histological diagnosis of gastric cancer by narrow band imaging-magnified endoscopy with and without acetic acid

Endoscopy International Open ◽

10.1055/a-0806-7275 ◽

2019 ◽

Vol 07 (02) ◽

pp. E155-E163 ◽

Cited By ~ 2

Author(s):

Takaaki Kishino ◽

Tsuneo Oyama ◽

Keita Funakawa ◽

Eiji Ishii ◽

Tetsuro Yamazato ◽

...

Keyword(s):

Gastric Cancer ◽

Diagnostic Accuracy ◽

Narrow Band ◽

Narrow Band Imaging ◽

Histological Type ◽

Surface Pattern ◽

Pit Pattern ◽

Undifferentiated Adenocarcinoma ◽

Surface Patterns ◽

Magnified Endoscopy

Abstract Background and study aims The usefulness of endoscopy for diagnosing histological type remains unclear. This study aimed to examine the diagnostic accuracy of white light endoscopy (WLE), magnified endoscopy with narrow band imaging (NBI-ME), and NBI-ME with acetic acid enhancement (NBI-AA) for histological type of gastric cancer. Patients and methods Patients with depressed-type gastric cancers resected by endoscopic submucosal dissection were prospectively enrolled, and 221 cases were analyzed. Histological type was diagnosed by WLE, followed by NBI-ME and NBI-AA. Histological type was classified into differentiated adenocarcinoma and undifferentiated adenocarcinoma. Histological type was diagnosed based on lesion color in WLE, surface patterns (pit, villi, and unclear) and vascular irregularities in NBI-ME, and surface patterns in NBI-AA. Results Histological types of target areas were differentiated adenocarcinoma and undifferentiated adenocarcinoma in 206 and 15 cases, respectively. Diagnostic accuracy of WLE, NBI-ME, and NBI-AA for the histological type was 96.4 % (213/221), 96.8 % (214/221), and 95.5 % (211/221), respectively. No significant differences were observed among modalities. Positive predictive value based on endoscopic findings in NBI-ME was 98.0 % (149/152) for the villi pattern, 100 % (19/19) for the irregular pit pattern, 100 % (9/9) for the unclear surface pattern with a vascular network, 90.3 % (28/31) for the unclear surface pattern with mild vascular irregularity, and 88.9 % (8/9) for the unclear surface pattern with severe vascular irregularity. Conclusions NBI-ME and NBI-AA did not show any advantages over WLE for diagnostic accuracy. Villi pattern, irregular pit pattern, and vascular network may be useful for identifying differentiated adenocarcinoma.

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