Epidemic Diseases of the Central Nervous System. By Arthur Salusbury MacNalty, m.a., m.d., f.r.c.p., d.p.h., Senior Medical Officer, Ministry of Health; late Examiner in Public Health, Universities of Oxford and Birmingham; Examiner in Hygiene, University of London. London: Faber and Gwyer, 1932. pp.194. Price 5s. net.

Public Health ◽  
1931 ◽  
Vol 45 ◽  
pp. 383
Keyword(s):  
Public Health ◽  
Central Nervous System ◽  
Nervous System ◽  
Medical Officer ◽  
Ministry Of Health ◽  
The Central Nervous System ◽  
Epidemic Diseases

scholarly journals Progress in Research on SARS-CoV-2 Infection Causing Neurological Diseases and Its Infection Mechanism

2021 ◽  
Vol 11 ◽  
Author(s):  
Lintao Wang ◽  
Zhiguang Ren ◽  
Li Ma ◽  
Yanjie Han ◽  
Wenqiang Wei ◽  
...  
Keyword(s):  
Public Health ◽  
Central Nervous System ◽  
Nervous System ◽  
Neurological Diseases ◽  
Public Health Problem ◽  
Neurological Complications ◽  
Major Public Health Problem ◽  
The Central Nervous System ◽  
The Impact ◽  
Great Harm

COVID-19 has spread rapidly worldwide since its outbreak and has now become a major public health problem. More and more evidence indicates that SARS-CoV-2 may not only affect the respiratory system but also cause great harm to the central nervous system. Therefore, it is extremely important to explore in-depth the impact of SARS-CoV-2 infection on the nervous system. In this paper, the possible mechanisms of SARS-CoV-2 invading the central nervous system during COVID-19, and the neurological complications caused by SARS-CoV-2 infection were reviewed.

scholarly journals POTENTIAL THERAPEUTIC EFFECT OF ZIKA VIRUS IN GLIOBLASTOMA TREATMENT

2018 ◽  
Vol 2 (4) ◽  
pp. 106-111
Author(s):  
Sâmia Israele Braz do Nascimento ◽  
Sheezara Teles Lira dos Santos ◽  
Bárbara Torquato Alves ◽  
Kevellyn Cruz Aguilera ◽  
Airton César Pinheiro de Menezes ◽  
...  
Keyword(s):  
Public Health ◽  
Central Nervous System ◽  
Nervous System ◽  
Zika Virus ◽  
Malignant Disease ◽  
Neurological Development ◽  
Metabolic Alterations ◽  
Therapeutic Advantage ◽  
The Central Nervous System ◽  
Worse Prognosis

Since the twentieth century, humanity has been experiencing a public health reality marked by numerous mosquito-borne diseases (belonging to the arthropod class), known as arboviruses. The Zika virus has become in recent years a risk to Brazilian and international public health due to its devastating effect due to its pathogenesis but also to fetal neurological development, causing serious health problems such as microcephaly and Guillain-Barré Syndrome, but also myelitis and meningoencephalitis. However, scientists studying the Zika virus have been trying to use the agent's ability to cause infections in healthy cells to attack and destroy cancer cells, such as the case of grade IV astrocytoma known as Gliobastoma Multiforme (GBM), which is a tumor of the very aggressive central nervous system and worse prognosis among primary cancers. As a result of effective therapy for GBM and the tropism of this etiological agent for brain cells, the hypothesis is that this virus would cause cell death in glioblastomas through metabolic alterations induced by the induced viral infection, but further studies must be carried out to demonstrate this therapeutic advantage in using the virus for the treatment of this malignant disease. Keywords: Zika virus; Gliobastoma Multiforme; Tumor of the Central Nervous System.

scholarly journals Cerebral Malaria and Toxoplasmosis: Could their Concomitant Presentation Worsen Psychotic Condition?

2020 ◽  
Vol 5 (2) ◽  
pp. 24-39
Author(s):  
Mohammed A. Ibrahim ◽  
Olayinka Atilola ◽  
Aminu Mohammed ◽  
Emmanuel J. Awosanya ◽  
Ismail A. Odetokun ◽  
...  
Keyword(s):  
Public Health ◽  
Central Nervous System ◽  
Nervous System ◽  
Single Infection ◽  
Parasitic Diseases ◽  
African Countries ◽  
Public Health Burden ◽  
Significant Public Health ◽  
The Central Nervous System ◽  
Sub Saharan

AbstractMalaria and toxoplasmosis are two important parasitic diseases with significant public health concerns in the Sub-Saharan African countries. Some aspects of pathogenesis of the two parasitic diseases involve the central nervous system manifesting neuropsychiatric disorders. Studies have implicated the single infection by Plasmodium spp. and Toxoplasma gondii in development of psychosis. Although concomitant infection of the two parasites suggests an aggravated psychotic condition, there is currently no reported study. This article reviewed some studies which implicated malaria and toxoplasmosis in psychosis. It further explored the likely role of concurrent infection by the parasites on psychosis, the dynamics of their pathology and possible effects of certain psychosis-associated cytokines and other biomolecules on the central nervous system. We recommend evidence-based research efforts in this field for the effective management of these two parasitic diseases to abate the public health burden of psychosis.

scholarly journals Effects of Riluzole on Nr2B subunits of NMDA receptors in rat migraine model

2019 ◽  
Vol 10 (3) ◽  
pp. 2242-2245
Author(s):  
Sankaran PK ◽  
Gunapriya Raghunath ◽  
Joy Ghoshal ◽  
Yuvaraj Maria Francis ◽  
Siva T ◽  
...  
Keyword(s):  
Public Health ◽  
Central Nervous System ◽  
Nervous System ◽  
Nmda Receptors ◽  
Sensory Neurons ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Intense Staining ◽  
Nerve Ganglion ◽  
The Central Nervous System

Migraine, a major public health problem, occurring due to the consequences of serial changes in the nerve ganglion leading to an imbalance in the excitation and inhibition. The is the major neurotransmitter in the central nervous system, causing to the sensory neurons leading to sensitization and . The present study was done to determine the effects of on the Nr2B of NMDA receptors after inducing a migraine. The rats were treated with after inducing migraine with nitroglycerin 10mg/kg. The nitroglycerin treated rats showed intense staining for NR2B , and there was a decrease in the expression after treatment. This study concludes that the NR2B are during migraine and can be used to control those by its property.

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