Haematology and morphological changes in young broiler chicks with experimentally induced hypoxia

1987 ◽  
Vol 43 (3) ◽  
pp. 331-338 ◽  
Author(s):  
M.H. MAXWELL ◽  
S.G. TULLETT ◽  
F.G. BURTON
Author(s):  
M.H. Maxwell

The ascites syndrome is a cardiopulmonary condition which affects young just-growing broiler chickens. It is identified by the accumulation of serous fluid in the abdominal cavity and birds die from chronic passive congestion and right ventricular heart failure. Many reports refer to its incidence among broilers maintained at altitudes greater than 3000 m. It is thought that hypoxia caused by decreased partial pressure of atmospheric oxygen (p02 results in a syndrome of cor pulmonale analogous to high mountain disease in cattle and is a major cause of ascites. From the mid 1980's, however, there have been more frequent reports that refer to the occurrence of spontaneous outbreaks of ascites in flocks maintained at moderate altitudes or even at sea level. At sea level, the increased frequency of this syndrome has still to be determined.Because the pathology of this syndrome is characterised by marked ascites, cardiomyopathy, pulmonary congestion and oedema and hepatopathy, much of this talk will concentrate on morphological changes, both spontaneous and induced, that have been identified in altitude - and sea level-reared broiler chicks. Histo/ultracytochemical techniques have been used to investigate the possible role of tissue oxygen underutilisation in the broiler ascites syndrome at low altitude.


2019 ◽  
Author(s):  
T. Monjur ◽  
T. Rahaman ◽  
M. S. Islam ◽  
K. A. Ferdous

Background: Nowadays poultry industry, an important sector is becoming a serious threat to public health due to the heavy metal exposure & accumulation in poultry tissues. Therefore, our recent study was aimed to investigate the toxic effects of lead (Pb) exposure in broiler chicken. Methods: A total number of 72 broiler chicks (Cobb-500, 12th day old) were assigned to four dietary treatments with three replicates. Control group received only basal diet without any supplementation. The other groups T1, T2 and T3 received feed with supplemented Pb @ 10, 30 and 50mg/kg feed, respectively. The body weight of each bird was weighed at 3 days interval. Results: Lead caused elevation of SGPT/ALT (P<0.01) and decreased serum creatinine attributed to pathological lesions including enlarged, pale & friable liver, swollen kidneys and splenomegaly in experimental groups. On histopathological examination, liver shows cirrhosis and necrosis in all treated groups. In the kidney, glomerulus was filled with reactive cells in group T1 while fibrosis and necrosis were found in groups T2 & T3. Conclusions: Lead toxicity in broiler had a dose-dependent effect on body weight gain, blood parameters, gross and histological changes.


2014 ◽  
Vol 113 (8) ◽  
pp. 2951-2960 ◽  
Author(s):  
A. Jabbar Tanweer ◽  
N. chand ◽  
U. Saddique ◽  
C. A. Bailey ◽  
R. U. Khan

2021 ◽  
Vol 52 (6) ◽  
pp. 1461-1474
Author(s):  
N. A. Ameen ◽  
N. R. Abdul Rahman ◽  
A H Hassan

A trial was conducted to study the effects of probiotic (Miaclost) supplement on experimentally induced hypocalcemic rickets in broiler chicks, a total of 180 one-day-old broiler chicks (Ross 308) were randomly divided into three equal groups 60 chicks per group with 3 replicates (20 birds /replicate) the dietary treatments consisted of a normal ration for G1, calcium-deficient ration 5% for G2 and calcium-deficient ration with addition of probiotics in drinking water for G3.Initial signs of rickets have been observed at 35-day of age in G2.while, in G1 and G3 no clinical signs observed, the gross lesions appeared enlargement of parathyroid gland, costochondral junction and increase in the width of growth plate of tibial bone of G2 whereas no gross lesions recorded in G1 and G3, the histopathological examination of parathyroid gland in G2 there were a focal parathyroid hyperplasia and increasing in numbers of syncytial cells and normal in G1 and G3, no intestinal histopathological changes in G1 and G2 and increase in height and width of the intestinal villi  in probiotic group G3. Marked increase in the thickness of proliferation zone within growth plate of tibia bone in G2 and normal thickness in G1 and G3. the serum biochemical analysis of calcium of G2 recorded significantly low level in G2 and high level in G3  comparatively with G1, finally the serum alkaline phosphatase values were high significantly in G2 and normal in G3, it is concluded that probiotic (MiaClost) can be used as prophylaxis to prevent hypocalcemic rickets in broiler chicks


Sign in / Sign up

Export Citation Format

Share Document