Efficacy and cost-effectiveness of drug and psychological treatments for common mental disorders in general health care in Goa, India: a randomised, controlled trial

The Lancet ◽  
2003 ◽  
Vol 361 (9351) ◽  
pp. 33-39 ◽  
Author(s):  
Vikram Patel ◽  
Daniel Chisholm ◽  
Sophia Rabe-Hesketh ◽  
Fiona Dias-Saxena ◽  
Gracy Andrew ◽  
...  
Keyword(s):  
Health Care ◽  
Cost Effectiveness ◽  
Randomised Controlled Trial ◽  
Mental Disorders ◽  
General Health ◽  
Common Mental Disorders ◽  
Controlled Trial ◽  
Psychological Treatments ◽  
Randomised Controlled

scholarly journals Optimising implementation strategies of the first scaleup of a primary care psychological intervention for common mental disorders in Sub-Saharan Africa: a mixed methods study protocol for the optimised Friendship Bench (OptFB)

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e045481
Author(s):  
Ruth Verhey ◽  
Charmaine Chitiyo ◽  
Sandra Ngonidzashe Mboweni ◽  
Ephraim Chiriseri ◽  
Dixon Chibanda ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Mental Disorders ◽  
Common Mental Disorders ◽  
Psychological Intervention ◽  
Controlled Trial ◽  
Implementation Strategies ◽  
Evaluation Framework ◽  
Sub Saharan Africa ◽  
Clinical Trial Registry ◽  
Randomised Controlled

IntroductionCommon mental disorders (CMDs) are a leading cause of disability globally. CMDs are highly prevalent in Zimbabwe and have been addressed by an evidence-based, task-shifting psychological intervention called the Friendship Bench (FB). The task-shifted FB programme guides clients through problem-solving therapy. It was scaled up across 36 implementation sites in Zimbabwe in 2016.Methods and analysisThis study will employ a mixed-method framework. It aims to: (1) use quantitative survey methodologies organised around the Reach, Effectiveness, Adoption and Implementation and Maintenance evaluation framework to assess the current scaleup of the FB intervention and classify 36 clinics according to levels of performance; (2) use qualitative focus group discussions and semistructured interviews organised around the Consolidated Framework for Implementation Research to analyse determinants of implementation success, as well as elucidate heterogeneity in implementation strategies through comparing high-performing and low-performing clinics; and (3) use the results from aims 1 and 2 to develop strategies to optimise the Friendship Bench intervention and apply this model in a cluster randomised controlled trial to evaluate potential improvements among low-performing clinics. The trial will be registered with the Pan African Clinical Trial Registry (www.pactr.org). The planned randomised controlled trial for the third research aim will be registered after completing aims one and two because the intervention is dependent on knowledge generated during these phases.Ethics and disseminationThe research protocol received full authorisation from the Medical Research Council of Zimbabwe (MRCZ A/242). It is anticipated that changes in data collection tools and consent forms will take place at all three phases of the study and approval from MRCZ will be sought. All interview partners will be asked for informed consent. The research team will prioritise open-access publications to disseminate research results.

scholarly journals Collaborative stepped care v. care as usual for common mental disorders: 8-month, cluster randomised controlled trial

2013 ◽  
Vol 203 (2) ◽  
pp. 132-139 ◽  
Author(s):  
Desiree B. Oosterbaan ◽  
Marc J. P. M. Verbraak ◽  
Berend Terluin ◽  
Adriaan W. Hoogendoorn ◽  
Wouter J. Peyrot ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Mental Disorders ◽  
Common Mental Disorders ◽  
Controlled Trial ◽  
Mental Healthcare ◽  
Cluster Randomised Controlled Trial ◽  
Stepped Care ◽  
Cluster Randomised ◽  
Post Test ◽  
Randomised Controlled

BackgroundThus far collaborative stepped care (CSC) studies have not incorporated self-help as a first step.AimsTo evaluate the effectiveness of CSC in the treatment of common mental disorders.MethodAn 8-month cluster randomised controlled trial comparing CSC to care as usual (CAU) (Dutch Trial Register identifier NTR1224). The CSC consisted of a stepped care approach guided by a psychiatric nurse in primary care with the addition of antidepressants dependent on the severity of the disorder, followed by cognitive–behavioural therapy in mental healthcare.ResultsTwenty general practitioners (GPs) and 8 psychiatric nurses were randomised to provide CSC or CAU. The GPs recruited 163 patients of whom 85% completed the post-test measurements. At 4-month mid-test CSC was superior to CAU: 74.7% (n = 68) v. 50.8% (n = 31) responders (P = 0.003). At 8-month post-test and 12-month follow-up no significant differences were found as the patients in the CAU group improved as well.ConclusionsTreatment within a CSC model resulted in an earlier treatment response compared with CAU.

scholarly journals Person-centred eHealth intervention for patients on sick leave due to common mental disorders: study protocol of a randomised controlled trial and process evaluation (PROMISE)

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e037515
Author(s):  
Matilda Cederberg ◽  
Lilas Ali ◽  
Inger Ekman ◽  
Kristina Glise ◽  
Ingibjörg H Jonsdottir ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Mental Disorders ◽  
Sick Leave ◽  
Self Efficacy ◽  
Standard Care ◽  
Common Mental Disorders ◽  
Controlled Trial ◽  
Control Group ◽  
Positive Effects ◽  
Randomised Controlled

IntroductionThe number of people dealing with common mental disorders (CMDs) is a major concern in many countries, including Sweden. Sickness absence resulting from CMDs is often long-lasting and advancing return to work is a complex process impacted by several factors, among which self-efficacy appears to be an important personal resource. Person-centred care (PCC) has previously shown positive effects on self-efficacy however this needs to be further investigated in relation to patients with CMDs and in an eHealth context.Methods and analysisThis study is an open randomised controlled trial comparing a control group receiving standard care with an intervention group receiving standard care plus PCC by telephone and a digital platform. The primary outcome measure is a composite score of changes in sick leave and self-efficacy. Participants will include 220 primary care patients on sick leave due to CMDs and data will mainly be collected through questionnaires at baseline and 3, 6, 12 and 24 months from the inclusion date. Inclusion is ongoing and expected to be completed during the fall of 2020. A process and health economic evaluation will also be conducted.Ethics and disseminationThis study was approved by the Regional Ethical Review Board in Gothenburg, Sweden. Results will be published in peer-reviewed scientific journals and presented at national and international scientific conferences. This project is part of a broader research programme conducted at the Gothenburg Centre for Person-Centred Care (GPCC), where extensive work is undertaken to disseminate knowledge on and implementation of PCC.Trial registration numberNCT03404583.

scholarly journals Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students: study protocol of a randomised controlled trial

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e028739 ◽  
Author(s):  
Eirini Karyotaki ◽  
Anke M Klein ◽  
Heleen Riper ◽  
Leonore de Wit ◽  
Lisa Krijnen ◽  
...  
Keyword(s):  
College Students ◽  
Randomised Controlled Trial ◽  
Mental Disorders ◽  
Common Mental Disorders ◽  
Controlled Trial ◽  
Tailored Intervention ◽  
Web Based ◽  
Symptoms Of Depression ◽  
Registration Number ◽  
Randomised Controlled

IntroductionThe college years are a peak period for the onset of common mental disorders. Poor mental health is associated with low academic attainment, physical, interpersonal and cognitive impairments. Universities can use online approaches to screen students for mental disorders and treat those in need. The present study aims to assess the effectiveness of a guided web-based transdiagnostic individually tailored intervention to treat students with symptoms of depression and/or anxiety.Methodsand analysisThe present study is a randomised controlled trial. Participants are Dutch college students (≥18 years) with mild to moderate depression and/or anxiety symptoms. The intervention is a guided web-based transdiagnostic individually tailored intervention that targets symptoms of depression and/or anxiety. The intervention consists of seven online sessions with a duration ranging from 4 to 7 weeks depending on individual progress. A booster session is administered 4 weeks after the completion of the seventh session. Primary outcome measures are the Patient Health Questionnaire for depression and the Generalised Anxiety Disorder 7-item scale for anxiety. These scales are administered at screening, post-treatment and follow-up assessments (6 and 12 months post-randomisation).Ethics and disseminationThe Medical Ethics Committee of the Vrije Universiteit Medical Centre has approved the protocol (registration number 2016.583, A2017.362andA2018.421). Results of the trial will be published in a peer-reviewed journal.Trial registration numberNTR6797; Pre-results.

Sign in / Sign up

Export Citation Format

Share Document