Inhibition of 5-aminolevulinic acid dehydratase in recombinant Escherichia coli using d-glucose

2003 ◽  
Vol 32 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Dae-Hee Lee ◽  
Woo-Jin Jun ◽  
Kyung-Mi Kim ◽  
Dong-Hoon Shin ◽  
Hong-Yon Cho ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Aminolevulinic Acid ◽  
Recombinant Escherichia Coli ◽  
Acid Dehydratase

scholarly journals delta-Aminolevulinic acid dehydratase deficiency can cause delta-aminolevulinate auxotrophy in Escherichia coli.

1991 ◽  
Vol 173 (1) ◽  
pp. 94-100 ◽  
Author(s):  
G P O'Neill ◽  
S Thorbjarnardóttir ◽  
U Michelsen ◽  
S Pálsson ◽  
D Söll ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Aminolevulinic Acid ◽  
Acid Dehydratase

Over-Production of Porphyrins and Heme in Heterotrophic Bacteria

1975 ◽  
Vol 30 (5-6) ◽  
pp. 425-426 ◽  
Author(s):  
W. K. Philipp-Dormston ◽  
M. Doss
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Heterotrophic Bacteria ◽  
Aminolevulinic Acid ◽  
Acid Dehydratase ◽  
Rate Limiting

Abstract In Escherichia coli, Pseudomonas aeruginosa, and A chromobacter metalcaligenes δ-aminolevulinic acid synthase and δ-aminolevulinic acid dehydratase appear to be the rate limiting enzymes of porphyrin and hemebiosynthesis. Bypassing of these enzymes by addition of 6-aminolevulinic acid or porphobilinogen results in overproduction of tetrapyrroles.

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