P4-043 Gene expression profiles of primary human astrocytes exposed to Abeta and ACT/ABETA complexes assessed using a global DNA microarray

2004 ◽  
Vol 25 ◽  
pp. S485
Author(s):  
Sabina M. Janciauskiene ◽  
Lennart Minthon ◽  
Gregory Vincic ◽  
Sun Xong-Xin ◽  
Crystal Baker ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Microarray ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Human Astrocytes

Isolation stress for 30 days alters hepatic gene expression profiles, especially with reference to lipid metabolism in mice

2009 ◽  
Vol 37 (2) ◽  
pp. 79-87 ◽  
Author(s):  
Keiko Motoyama ◽  
Yuji Nakai ◽  
Tomoya Miyashita ◽  
Yuichiro Fukui ◽  
Maki Morita ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lipid Metabolism ◽  
Dna Microarray ◽  
Social Stress ◽  
Secretory Pathway ◽  
Expression Profiles ◽  
Regulatory Element ◽  
Gene Expression Profiles ◽  
Hepatic Gene Expression ◽  
Isolation Stress

To elucidate the physiological responses to a social stressor, we exposed mice to an isolation stress and analyzed their hepatic gene expression profiles using a DNA microarray. Male BALB/c mice were exposed to isolation stress for 30 days, and then hepatic RNA was sampled and subjected to DNA microarray analysis. The isolation stress altered the expression of 420 genes (after considering the false discovery rate). Gene Ontology analysis of these differentially expressed genes indicated that the stress remarkably downregulated the lipid metabolism-related pathway through peroxisome proliferator-activated receptor-α, while the lipid biosynthesis pathway controlled by sterol regulatory element binding factor 1, Golgi vesicle transport, and secretory pathway-related genes were significantly upregulated. These results suggest that isolation for 30 days with a mild and consecutive social stress regulates the systems for lipid metabolism and also causes endoplasmic reticulum stress in mouse liver.

Gene expression profiles of cardiomyocytes in rat autoimmune myocarditis by DNA microarray and increase of regenerating gene family

2008 ◽  
Vol 152 (3) ◽  
pp. 119-127 ◽  
Author(s):  
Ritsuo Watanabe ◽  
Haruo Hanawa ◽  
Tsuyoshi Yoshida ◽  
Masahiro Ito ◽  
Manabu Isoda ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Family ◽  
Dna Microarray ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Autoimmune Myocarditis

Gene expression profiles in human nasal polyp tissues studied by means of DNA microarray

2004 ◽  
Vol 114 (4) ◽  
pp. 783-790 ◽  
Author(s):  
Zheng Liu ◽  
Jean Kim ◽  
Joseph P. Sypek ◽  
I-Ming Wang ◽  
Heidi Horton ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Microarray ◽  
Nasal Polyp ◽  
Expression Profiles ◽  
Gene Expression Profiles
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