Behaviour of gelatinisation and viscosity in soy-sweet potato mixtures by single screw extrusion: A response surface analysis

1998 ◽  
Vol 38 (3) ◽  
pp. 369-379 ◽  
Author(s):  
M.O. Iwe ◽  
I. Wolters ◽  
G. Gort ◽  
W. Stolp ◽  
D.J. van Zuilichem
2016 ◽  
Vol 33 (2) ◽  
pp. 168-190 ◽  
Author(s):  
Tingrui Fu ◽  
Barry Haworth ◽  
Leno Mascia

The process dynamics of single-screw extrusion on mixtures of polypropylene (PP) and recycled PP were studied using a statistical, design of experiments (DoE) approach. For a conventional screw design, the barrel temperature, screw speed and two vastly different melt viscosity polypropylene mixtures were selected as the independent factors, whilst melt pressure, mass output, screw torque and temperature rise at the die due to shear heating were the dependent responses. A central composite design (CCD) in the framework of response surface methodology (RSM) was constructed, and an analysis of variance (ANOVA) was carried out to determine the significance of the response surface models. The resulting statistical and response surface predictions have demonstrated that the low viscosity component concentration in the blend is a dominating factor on melt pressure and screw torque, apart from the expected effect of screw speed on output. Viscous heating is affected only by screw speed and recycled polypropylene concentration. Furthermore, the predictions have identified a wider process operating window with increased low-viscosity component concentration. The data confirm that statistical tools make quantitative predictions for the effects of experimental process variables, in accordance with the expected qualitative trends towards process optimisation, providing scope towards its application in scaled-up industrial processes.


Author(s):  
Turki Al-Khalifah ◽  
Abdul Aabid ◽  
Sher Afghan Khan ◽  
Muhammad Hanafi Bin Azami ◽  
Muneer Baig

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Patrick Schwarz ◽  
Anne-Laure Bidaud ◽  
Eric Dannaoui

AbstractThe in vitro interactions of isavuconazole with colistin were evaluated against 15 clinical Candida auris isolates by a microdilution checkerboard technique based on the EUCAST reference method for antifungal susceptibility testing and by agar diffusion using isavuconazole gradient concentration strips with or without colistin incorporated RPMI agar. Interpretation of the checkerboard results was done by the fractional inhibitory concentration index and by response surface analysis based on the Bliss model. By checkerboard, combination was synergistic for 93% of the isolates when interpretation of the data was done by fractional inhibitory concentration index, and for 80% of the isolates by response surface analysis interpretation. By agar diffusion test, although all MICs in combination decreased compared to isavuconazole alone, only 13% of the isolates met the definition of synergy. Essential agreement of EUCAST and gradient concentration strip MICs at +/− 2 log2 dilutions was 93.3%. Antagonistic interactions were never observed for any technique or interpretation model used.


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