Evaluating new approach methodologies for consumer-based risk assessments: challenges and future perspectives

2021 ◽  
Vol 350 ◽  
pp. S69
Author(s):  
A. Middleton ◽  
S. Cable ◽  
P. Russell ◽  
M. Baltazar ◽  
B. Nicol ◽  
...  
Keyword(s):  
Risk Assessments ◽  
Future Perspectives ◽  
New Approach

scholarly journals Urban, industrial and technological risks. Synthesis of the elements of vulnerability of the city of Hassi-Messaoud

2020 ◽  
Vol 12 ◽  
Author(s):  
Lahcene Bouzouaid ◽  
Moussadek Benabbas
Keyword(s):  
Urban Space ◽  
Job Search ◽  
Population Distribution ◽  
Risk Assessments ◽  
Demographic Development ◽  
New Approach ◽  
Different Types ◽  
Specific Factors ◽  
The City

Abstract Today, Algeria is one of the developing countries that are engaging seriously into a new approach consisting of all kinds of combined risk assessments for better prevention them. Note that, this is a fairly important parameter, that is, the safety of people and property. However, the magnitude of the risk, of whatever nature, affects a variety of diversified aspects (Human, economic, technical and environmental). This study presented a case study, which is sometimes paradoxical, seeing that it is the result of the combination of all risk factors and specific factors related to them connected to a fragile urban environment: Hassi-Messaoud. It is well known that Hassi-Messaoud is one of the most important city for Algeria's economy; in which the demographic development is mainly known by incessant flows of immigrants, motivated essentially by job search. This arbitrary of population distribution exposes this city to a certain danger; especially as Hassi-Messaoud is in a zone subject to a probable risk expressed here by being characteristic of an oil zone. Thus, this article aimed to provide elements of risk assessment related to oil activity. This approach could conclude that, through a schematic scale, the different types and levels of exposure and vulnerability could be identified, that is, characteristics of the urban space in question.

History of EPI Suite™ and future perspectives on chemical property estimation in US Toxic Substances Control Act new chemical risk assessments

2017 ◽  
Vol 19 (3) ◽  
pp. 203-212 ◽  
Author(s):  
Marcella L. Card ◽  
Vicente Gomez-Alvarez ◽  
Wen-Hsiung Lee ◽  
David G. Lynch ◽  
Nerija S. Orentas ◽  
...  
Keyword(s):  
Chemical Property ◽  
Risk Assessments ◽  
Toxic Substances ◽  
Future Perspectives ◽  
Qsar Modeling ◽  
Chemical Risk ◽  
The Past ◽  
Property Estimation ◽  
History Of ◽  
Toxic Substances Control Act

A discussion of the past developments, current practices, and future opportunities in QSAR modeling for new chemical risk assessments.

Rolling stones and tree rings

2013 ◽  
Vol 37 (5) ◽  
pp. 701-716 ◽  
Author(s):  
Daniel Trappmann ◽  
Christophe Corona ◽  
Markus Stoffel
Keyword(s):  
Tree Ring ◽  
Quantitative Estimate ◽  
Progress Report ◽  
Future Perspectives ◽  
New Approach ◽  
The Past ◽  
Broadleaved Tree Species ◽  
Broadleaved Tree ◽  
Assessment Procedures ◽  
Conifer Trees

This progress report focuses on the contribution of tree-ring series to rockfall research and on recent development and challenges in the field. Dendrogeomorphic techniques have been used extensively since the early 2000s and several approaches have been developed to extract rockfall signals from tree-ring records of conifer trees. The reconstruction of rockfall chronologies has been hampered in the past by sample sizes that decrease as one goes back in time, as well as by a paucity of studies that include broadleaved tree species, which are in fact quite common in rockfall-prone environments. In this report, we propose a new approach considering impact probability and quantification of uncertainty in the reconstruction of rockfall time series as well as a quantitative estimate of presumably missed events. In addition, we outline new approaches and future perspectives for the inclusion of woody vegetation in hazard assessment procedures, and end with future thematic perspectives.

scholarly journals Current Applications and Future Perspectives of Fluorescence Light Energy Biomodulation in Veterinary Medicine

2021 ◽  
Vol 8 (2) ◽  
pp. 20
Author(s):  
Andrea Marchegiani ◽  
Andrea Spaterna ◽  
Matteo Cerquetella
Keyword(s):  
Veterinary Medicine ◽  
Standard Care ◽  
State Of The Art ◽  
Future Scenarios ◽  
Clinical Use ◽  
Future Perspectives ◽  
Current Standard ◽  
New Approach ◽  
Potential Applications ◽  
Fluorescence Light

The purpose of this review is to determine the state of the art of the mode of action and potential applications of fluorescence photobiomodulation in veterinary medicine. After a summary of the assets that have led the translation of such light-based therapies from bench side into clinical use, recent advances in canine dermatology using this brand-new approach are presented, and future scenarios where this type of care may provide benefits over the current standard care are highlighted.

scholarly journals Ecological Thresholds of Toxicological Concern: A Review

2021 ◽  
Vol 3 ◽  
Author(s):  
Mace G. Barron ◽  
Ryan R. Otter ◽  
Kristin A. Connors ◽  
Aude Kienzler ◽  
Michelle R. Embry
Keyword(s):  
Review Article ◽  
Risk Assessments ◽  
Toxicity Data ◽  
Ongoing Research ◽  
New Approach ◽  
Ecological Thresholds ◽  
Ecological Threshold ◽  
Recent Developments ◽  
Potential Applications ◽  
Computational Platform

The ecological threshold of toxicological concern (ecoTTC) is analogous to traditional human health-based TTCs but with derivation and application to ecological species. An ecoTTC is computed from the probability distribution of predicted no effect concentrations (PNECs) derived from either chronic or extrapolated acute toxicity data for toxicologically or chemically similar groups of chemicals. There has been increasing interest in using ecoTTCs in screening level environmental risk assessments and a computational platform has been developed for derivation with aquatic species toxicity data (https://envirotoxdatabase.org/). Current research and development areas include assessing mode of action-based chemical groupings, conservatism in estimated PNECs and ecoTTCs compared to existing regulatory values, and the influence of taxa (e.g., algae, invertebrates, and fish) composition in the distribution of PNEC values. The ecoTTC continues to develop as a valuable alternative strategy within the toolbox of traditional and new approach methods for ecological chemical assessment. This brief review article describes the ecoTTC concept and potential applications in ecological risk assessment, provides an overview of the ecoTTC workflow and how the values can be derived, and highlights recent developments and ongoing research. Future applications of ecoTTC concept in different disciplines are discussed along with opportunities for its use.

The O–C diagrams of minor planets − a new approach to modelling the rotation

1999 ◽  
Vol 173 ◽  
pp. 185-188
Author(s):  
Gy. Szabó ◽  
K. Sárneczky ◽  
L.L. Kiss
Keyword(s):  
Error Analysis ◽  
Time Dependence ◽  
Theoretical Work ◽  
Minor Planet ◽  
Minor Planets ◽  
New Approach ◽  
Preliminary Results ◽  
Ccd Observations

AbstractA widely used tool in studying quasi-monoperiodic processes is the O–C diagram. This paper deals with the application of this diagram in minor planet studies. The main difference between our approach and the classical O–C diagram is that we transform the epoch (=time) dependence into the geocentric longitude domain. We outline a rotation modelling using this modified O–C and illustrate the abilities with detailed error analysis. The primary assumption, that the monotonity and the shape of this diagram is (almost) independent of the geometry of the asteroids is discussed and tested. The monotonity enables an unambiguous distinction between the prograde and retrograde rotation, thus the four-fold (or in some cases the two-fold) ambiguities can be avoided. This turned out to be the main advantage of the O–C examination. As an extension to the theoretical work, we present some preliminary results on 1727 Mette based on new CCD observations.

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