Arteriosclerotic Heart Disease in the Elderly

1986 ◽  
Vol 4 (2) ◽  
pp. 253-262 ◽  
Author(s):  
Francis G. Dunn
1987 ◽  
Vol 17 (4) ◽  
pp. 321-326 ◽  
Author(s):  
John B. Wood

The relationship between birthday and deathday has been called an artifact due to the continuous depletion of the population with age. However, while the population decreases with age, the death rate increases. These two influences cancel each other at ages seventy-five to eighty-four. The decreasing population dominates at older ages, but the situation is reversed at younger ages. The results account for no more than one-third of the size of the large-sample effects observed among the elderly. There is still a 33 percent excess of deaths resulting from heart disease among married people ages seventy-five and older in the three-day period centered at the birthday.


Author(s):  
Michael Anderson ◽  
Corinne Roughley

The principal reported causes of death have changed dramatically since the 1860s, though changes in categorization of causes and improved diagnosis make it difficult to be precise about timings. Diseases particularly affecting children such as measles and whooping cough largely disappeared as killers by the 1950s. Deaths particularly linked to unclean environments and poor sanitary infrastructure also declined, though some can kill babies and the elderly even today. Pulmonary tuberculosis and bronchitis were eventually largely controlled. Reported cancer, stroke, and heart disease mortality showed upward trends well into the second half of the twentieth century, though some of this was linked to diagnostic improvement. Both fell in the last decades of our period, but Scotland still had among the highest rates in Western Europe. Deaths from accidents and drowning saw significant falls since World War Two but, especially in the past 25 years, suicide, and alcohol and drug-related deaths rose.


2000 ◽  
Vol 18 (4) ◽  
pp. 461-464 ◽  
Author(s):  
Barbara Gryglewska ◽  
Tomasz Grodzicki ◽  
Danuta Czarnecka ◽  
Kalina Kaweoicka-Jaszcz ◽  
Józef Kocemba

Author(s):  
Harukuni Akita ◽  
Miyao Matsubara ◽  
Hitoshi Shibuya ◽  
Hirotoshi Fuda ◽  
Hitoshi Chiba

Background Lipoprotein(a) [Lp(a)] is a risk factor for atherosclerosis and increases with age. The purpose of this study was to determine the effect of ageing on Lp(a) for three different apo(a) phenotypes. Methods We measured plasma Lp(a) concentrations in 551 unrelated Japanese subjects (20-88 years of age). We performed statistical analyses separately for three apo(a) phenotypes: the low-molecular-weight (LMW) phenotype with the F, B or S1 isoform, the intermediate-molecular-weight (IMW) phenotype with the S2 isoform and the high-molecular-weight (HMW) phenotype with the S3 or S4 isoform. Results For each phenotype, the mean plasma Lp(a) concentration and the frequency of Lp(a) concentrations ≥ 250 mg/L increased with age. Further, a statistically significant difference was always found between the younger subjects (20-39 years of age) and the elderly (over 60 years). The frequency of coronary heart disease increased with age, particularly for the LMW and IMW phenotypes. Conclusions We conclude that ageing elevates plasma Lp(a) concentrations, which may have a role in the prevalence of coronary heart disease in the elderly, especially those with the LMW or IMW phenotypes.


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