Pyridoxine and pyridoxamine inhibits superoxide radicals and prevents lipid peroxidation, protein glycosylation, and (Na+ + K+)-ATPase activity reduction in high glucose-treated human erythrocytes

2001 ◽  
Vol 30 (3) ◽  
pp. 232-237 ◽  
Author(s):  
Sushil K Jain ◽  
Gideon Lim
Keyword(s):  
Lipid Peroxidation ◽  
Atpase Activity ◽  
High Glucose ◽  
Human Erythrocytes ◽  
Protein Glycosylation ◽  
Superoxide Radicals

Trivalent Chromium Inhibits Protein Glycosylation and Lipid Peroxidation in High Glucose-Treated Erythrocytes

2006 ◽  
Vol 8 (1-2) ◽  
pp. 238-241 ◽  
Author(s):  
Sushil K. Jain ◽  
Parag Patel ◽  
Kimberly Rogier ◽  
Sumati K. Jain
Keyword(s):  
Lipid Peroxidation ◽  
High Glucose ◽  
Trivalent Chromium ◽  
Protein Glycosylation

scholarly journals Effects of Three Kinds of Curcuminoids on Anti-Oxidative System and Membrane Deformation of Human Peripheral Blood Erythrocytes in High Glucose Levels

2015 ◽  
Vol 35 (2) ◽  
pp. 789-802 ◽  
Author(s):  
Wei Yang ◽  
Juan Fu ◽  
Miao Yu ◽  
Di Wang ◽  
Ying Rong ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
High Glucose ◽  
Human Peripheral Blood ◽  
Human Erythrocytes ◽  
Protein Glycation ◽  
Bioactive Constituents ◽  
Blood Samples ◽  
Glucose Levels ◽  
Stress Damage

Background/Aims: Curcuminoids are the main bioactive constituents of the rhizome of turmeric. Erythrocytes lesions in diabetes are probably related to hyperglycemia and protein glycation. It has been reported that curcumin prevent lipid peroxidation. However, reports on the effects of demethoxycurcumin and bis-demethoxycurcumin on human erythrocytes at high glucose levels are scarce. Our aim is to investigate the effect of curcuminoids on oxidative stress and membrane of erythrocytes exposed to hyperglycemic condition. Methods: In this study, the different blood samples were treated with two doses of glucose (10 or 30 mM) to mimic hyperglycemia in the presence or absence of three kinds of curcuminoids (5 or 10 μM) in a medium at 37 °C for 24 h (Each experiment consists of 20 blood samples from 10 male and 10 female volunteers). The malondialdehyde was checked by HPLC, antioxidase (GSH and GSSG) were measured by LC/MS, SOD was checked by WST-1 kit, morphology and phospholipid symmetry were detected by flow cytometry, confocal scanning microscope and scanning electron microscope. Results: The results illustrated that all three curcuminoids reduce oxidative stress damage on the membrane and maintain a better profile for erythrocytes. Furthermore, three curcuminoids had benefit effects on antioxidase. Conclusion: The three kinds of curcuminoids supplementation may prevent lipid peroxidation at different intensity and membrane dysfunction of human erythrocytes in hyperglycemia.

The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations

2013 ◽  
Vol 148 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Andréia C.F. Salgueiro ◽  
Carina Q. Leal ◽  
Matheus C. Bianchini ◽  
Ianeli O. Prado ◽  
Andreas S.L. Mendez ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
High Glucose ◽  
Human Erythrocytes ◽  
Sh Groups ◽  
Bauhinia Forficata

Ca-ATPase Activity of Human Red Cell Ghosts: Preeclampsia, Lipid Peroxidation and MgSO4

2009 ◽  
Vol 28 (4) ◽  
pp. 390-401 ◽  
Author(s):  
Patricia Gutiérrez ◽  
Cilia Abad ◽  
Teresa Proverbio ◽  
Sandy Piñero ◽  
Reinaldo Marín ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Atpase Activity ◽  
Red Cell
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