Baclofen in cannabis dependence syndrome - a open-label study and a brief follow up

AimTo study the effect of baclofen in preventing drug use in persons with cannabis misuse.MethodologyAn open label study to asses the effect of baclofen in treating persons with cannabis dependence (ICD-10 criteria) with assessments of outcome every month for a period of three months.Results20 male subjects (mean age of 29.70 ± 10.19 years) with a mean age at development of dependence of 20.75 ± 09.34 years and mean duration of cannabis use of 89.40 ± 57.41 months, were treated with baclofen (mean dose of 33.75 ± 04.83 mg./day). At three months 12 subjects (60%) completely stopped, 6 subjects (30%) decreased the frequency and 2 subjects (10%) continued the same frequency of the cannabis intake.ConclusionOur findings provide preliminary support for the use of baclofen in maintaining abstinence and improving outcome in patients with cannabis dependence.

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Bortezomib, thalidomide, and dexamethasone followed by double autologous haematopoietic stem-cell transplantation for newly diagnosed multiple myeloma (GIMEMA-MMY-3006): long-term follow-up analysis of a randomised phase 3, open-label study

The Lancet Haematology ◽

10.1016/s2352-3026(20)30323-9 ◽

2020 ◽

Vol 7 (12) ◽

pp. e861-e873 ◽

Cited By ~ 1

Author(s):

Paola Tacchetti ◽

Lucia Pantani ◽

Francesca Patriarca ◽

Maria Teresa Petrucci ◽

Elena Zamagni ◽

...

Keyword(s):

Haematopoietic Stem Cell Transplantation ◽

Haematopoietic Stem Cell ◽

Newly Diagnosed ◽

Open Label ◽

Phase 3 ◽

Open Label Study ◽

Label Study ◽

Long Term Follow Up

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Long-term follow-up of DYT1 dystonia patients treated by deep brain stimulation: An open-label study

Movement Disorders ◽

10.1002/mds.22802 ◽

2010 ◽

Vol 25 (3) ◽

pp. 289-299 ◽

Cited By ~ 98

Author(s):

Laura Cif ◽

Xavier Vasques ◽

Victoria Gonzalez ◽

Patrice Ravel ◽

Brigitte Biolsi ◽

...

Keyword(s):

Deep Brain Stimulation ◽

Brain Stimulation ◽

Open Label ◽

Open Label Study ◽

Label Study ◽

Dyt1 Dystonia ◽

Long Term Follow Up ◽

Deep Brain

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Pharmacokinetic properties of lansoprazole (30-mg enteric-coated capsules) and its metabolites: A single-dose, open-label study in healthy Chinese male subjects

Current Therapeutic Research ◽

10.1016/j.curtheres.2009.05.002 ◽

2009 ◽

Vol 70 (3) ◽

pp. 228-239 ◽

Cited By ~ 7

Author(s):

Min Song ◽

Xuan Gao ◽

Tai-Jun Hang ◽

Ai-Dong Wen

Keyword(s):

Single Dose ◽

Open Label ◽

Open Label Study ◽

Label Study ◽

Pharmacokinetic Properties ◽

Healthy Chinese ◽

Enteric Coated ◽

Male Subjects ◽

Chinese Male

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A prospective, randomized, open-label study of steroid withdrawal in pancreas transplantation—a preliminary report with 6-month follow-up

Transplantation Proceedings ◽

10.1016/s0041-1345(00)02632-4 ◽

2001 ◽

Vol 33 (1-2) ◽

pp. 1663-1664 ◽

Cited By ~ 34

Author(s):

R.W.G Gruessner ◽

D.E.R Sutherland ◽

E Parr ◽

A Humar ◽

A.C Gruessner

Keyword(s):

Pancreas Transplantation ◽

Preliminary Report ◽

Steroid Withdrawal ◽

Open Label ◽

Open Label Study ◽

Label Study

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Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study

The Lancet Oncology ◽

10.1016/s1470-2045(14)70012-9 ◽

2014 ◽

Vol 15 (3) ◽

pp. 323-332 ◽

Cited By ~ 625

Author(s):

Grant A McArthur ◽

Paul B Chapman ◽

Caroline Robert ◽

James Larkin ◽

John B Haanen ◽

...

Keyword(s):

Open Label ◽

Phase 3 ◽

Open Label Study ◽

Label Study ◽

Safety And Efficacy

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P-166 - Dysphoric manic symptoms are probably depressive symptoms. an open label study in bipolar i mixed - one-year follow up

European Psychiatry ◽

10.1016/s0924-9338(12)74333-x ◽

2012 ◽

Vol 27 ◽

pp. 1

Author(s):

G. Callista ◽

E. Daneluzzo

Keyword(s):

Depressive Symptoms ◽

Open Label ◽

Open Label Study ◽

Label Study ◽

Manic Symptoms ◽

One Year

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The Effect of Fenoprofen Calcium (Nalfon) on Levels of Rheumatoid Factor in Patients with Rheumatoid Arthritis

Journal of International Medical Research ◽

10.1177/030006057300100205 ◽

1973 ◽

Vol 1 (2) ◽

pp. 412-416

Author(s):

Joan E Himes ◽

Ivan F Duff

Keyword(s):

Rheumatoid Arthritis ◽

Rheumatoid Factor ◽

Open Label ◽

Open Label Study ◽

Label Study ◽

The Mean ◽

Baseline Levels ◽

One Year

In 88.9% of a group of 18 patients with rheumatoid arthritis participating in an open-label study with fenoprofen calcium (Nalfon), there was observed a mean litre decrease in level of rheumatoid factor as compared to baseline levels. In follow-up, three months to one year later, a uniform litre increase above the mean level of the study period had occurred. In all cases the titre returned to baseline levels or higher.

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