Selenium supplementation of Chinese women with habitually low selenium intake increases plasma selenium, plasma glutathione peroxidase activity, and milk selenium, but not milk glutathione peroxidase activity11Published with the approval of the Oregon State University Agricultural Experiment Station as Technical Paper number 11599. This research was supported in part by Public Health Service Research Grant number DK 38341 from the National Institute of Diabetes and Digestive and Kidney Diseases.

2000 ◽  
Vol 11 (6) ◽  
pp. 341-347 ◽  
Author(s):  
M.A Moore ◽  
R.C Wandera ◽  
Y.-M Xia ◽  
S.-H Du ◽  
J.A Butler ◽  
...  
Keyword(s):  
Glutathione Peroxidase ◽  
Chinese Women ◽  
Kidney Diseases ◽  
Service Research ◽  
Public Health Service Research ◽  
State University ◽  
Plasma Selenium ◽  
Plasma Glutathione Peroxidase ◽  
Agricultural Experiment ◽  
Low Selenium

Determination of selenium concentration and glutathione peroxidase activity in plasma and erythrocytes.

1982 ◽  
Vol 28 (2) ◽  
pp. 311-316 ◽  
Author(s):  
P A Pleban ◽  
A Munyani ◽  
J Beachum
Keyword(s):  
Glutathione Peroxidase ◽  
Peroxidase Activity ◽  
Zeeman Effect ◽  
Selenium Concentration ◽  
Glutathione Peroxidase Activity ◽  
Plasma Selenium ◽  
Plasma Glutathione Peroxidase ◽  
Flameless Atomic Absorption Spectroscopy ◽  
Plasma Glutathione

Abstract We determined selenium concentrations and activities of the selenoenzyme, glutathione peroxidase (EC 1.11.1.9), in the plasma and erythrocytes of 38 apparently healthy women. We determined selenium concentrations directly by polarized Zeeman-effect flameless atomic absorption spectroscopy. Within-run precision studies for the assays gave CVs of 5.6% for a mean erythrocyte selenium concentration of 149.9 (SD 8.3) microgram/L (n = 10) and 6.4% for a mean plasma selenium concentration of 97.3 (SD 6.2) microgram/L (n = 12). For the women, mean selenium concentrations were 141.4 (SD 14.3) microgram/L of erythrocytes [0.49 (SD 0.07) microgram/g of hemoglobin and 96.3 (SD 14.2) microgram/L of plasma. Glutathione peroxidase activities were measured by a modification of the method of Paglia and Valentine (J. Lab. Clin. Med. 70: 158--169, 1967). Within-run precision studies for the glutathione peroxidase assays gave CVs of 12.8% for mean erythrocyte glutathione peroxidase activity of 77.2 (SD 9.9) U/g of hemoglobin (n = 13), and 8.1% for mean plasma activity of 312.5 (SD 25.2) U/L (n = 11). Mean enzyme activity was 78.7 (SD 12.9) U/g of hemoglobin for erythrocytes and 424 (SD 40) U/L for plasma. Erythrocyte selenium concentrations and glutathione peroxidase activities were positively, but poorly, correlated (r = 0.41, p less than 0.01).

Selenium deficiency as a possible factor in the pathogenesis of myxoedematous endemic cretinism

1987 ◽  
Vol 114 (4) ◽  
pp. 497-502 ◽  
Author(s):  
P. Goyens ◽  
J. Golstein ◽  
B. Nsombola ◽  
H. Vis ◽  
J. E. Dumont
Keyword(s):  
Glutathione Peroxidase ◽  
Oxygen Toxicity ◽  
Selenium Deficiency ◽  
Serum Levels ◽  
Serum Selenium ◽  
Endemic Cretinism ◽  
Plasma Glutathione Peroxidase ◽  
Plasma Glutathione ◽  
Low Selenium

Abstract. Myxoedematous endemic cretinism is prevalent in African goitre endemies. It has been related to a thyroid 'exhaustion' atrophy occurring near birth. It is proposed that this might result from the low resistance of a fragile tissue to enhanced H2O2 generation under intense thyroid stimulation by thyrotropin. In support of this hypothesis, low selenium and glutathione peroxidase serum levels have been found in the African endemic area of the Idjwi Island (Kivu, Zaire). Serum selenium and plasma glutathione peroxidase were lower in the area of high endemicity of goitre and cretinism (Northern part of the Island). However, only the former difference is statistically significant. These data thus suggest a role of oligoelements and oxygen toxicity in the pathogenesis of endemic cretinism.

scholarly journals Plasma Selenium-dependent Glutathione Peroxidase

1989 ◽  
Vol 264 (27) ◽  
pp. 15850-15855
Author(s):  
N Avissar ◽  
J C Whitin ◽  
P Z Allen ◽  
D D Wagner ◽  
P Liegey ◽  
...  
Keyword(s):  
Glutathione Peroxidase ◽  
Plasma Selenium

Mechanism of plasma glutathione peroxidase production in bovine adipocytes

2006 ◽  
Vol 326 (1) ◽  
pp. 139-147 ◽  
Author(s):  
Tadashi Yamasaki ◽  
Koji Tahara ◽  
Shoichi Takano ◽  
Miho Inoue-Murayama ◽  
Michael T. Rose ◽  
...  
Keyword(s):  
Glutathione Peroxidase ◽  
Plasma Glutathione Peroxidase ◽  
Plasma Glutathione ◽  
Bovine Adipocytes
Sign in / Sign up

Export Citation Format

Share Document