Repligen set to expand its hollow-fibre membrane production capabilities by acquiring Polymem

The contact of blood with the artificial extracorporeal circuit causes a systemic inflammatory response due to blood activation. In this study, we compared two different paediatric membrane oxygenators used for extracorporeal circulation: a hollow fibre membrane oxygenator (Dideco Masterflo D-701, n=10), and a flat sheet silicone membrane oxygenator (Avecor Kolobow 800-2A, n=10). Blood compatibility was indicated by measuring complement activation as well as leukocyte and platelet activation. In patients perfused with a flat sheet membrane oxygenator, concentrations of complement split products C3a were significantly increased 30 minutes after the start of bypass (p<0.01), whereas only a mild increase of C3a was found in patients perfused with a hollow fibre membrane oxygenator. Leukocyte and platelet counts dropped uniformly in both groups after the start of bypass mainly due to hemodilution. Activation of leukocytes and platelets identified by both plasma β-glucuronidase and β-thromboglobulin was similar in both groups. Infants perfused with a flat sheet membrane oxygenator received significantly more donor blood than those perfused with a hollow fibre oxygenator (p<0.05). These results indicate that when used during paediatric cardiopulmonary bypass, a flat sheet membrane oxygenator has a higher complement activity than a hollow fibre membrane oxygenator, which is probably due to the relatively larger blood-surface contacting area of the oxygenator.

Download Full-text

Recovery of Sulfur Dioxide Using Non-Dispersive Absorption

International Journal of Chemical Reactor Engineering ◽

10.2202/1542-6580.1456 ◽

2007 ◽

Vol 5 (1) ◽

Cited By ~ 3

Author(s):

Patricia Luis ◽

Inmaculada Ortiz ◽

Rubén Aldaco ◽

Aurora Garea ◽

Ángel Irabien

Keyword(s):

Gas Phase ◽

Plug Flow ◽

Hollow Fibre ◽

Absorption Efficiency ◽

Environmental Risks ◽

Process Efficiency ◽

Selective Absorption ◽

Hollow Fibre Membrane ◽

Fibre Membrane ◽

Removal Of So2

Removal of SO2 from gas emissions by selective absorption into a liquid is a common method to reduce air pollution and environmental risks. The absorption efficiency is determined by the interaction between the gases and the liquid. A great number of gas desulphurization methods have been developed where aqueous or organic solvents are used as sorbents.N,N-dimethylaniline (DMA) is an organic solvent used in the industry because its affinity with SO2. This absorption is neither too strong nor too weak, thus absorption and desorption can occur leading to a regenerative process where SO2 can be recovered. However, a direct contact between SO2 and DMA leads to several environmental problems caused by solvent evaporation and drops dragging into the gas stream.In order to increase the process efficiency and reduce environmental risks, a non-dispersive absorption process using hollow fibre membrane modules is developed in this work for a solvent zero emission process. The mass transfer into a fibre may be described by three main assumptions: gas-phase laminar flow, gas-phase plug-flow and gas-phase mixing. A numerical calculation was carried out to establish the performance of a hollow fibre membrane contactor for the removal of SO2 when water and N,N-dimethylaniline are used as sorbents in order to compare both, wetted and non-wetted operating modes.

Download Full-text

THE FEASIBILITY OF KAOLIN AS MAIN MATERIAL FOR LOW COST POROUS CERAMIC HOLLOW FIBRE MEMBRANE PREPARED USING COMBINED PHASE INVERSION AND SINTERING TECHNIQUE

Jurnal Teknologi ◽

10.11113/jt.v79.10434 ◽

2017 ◽

Vol 79 (1-2) ◽

Cited By ~ 3

Author(s):

Siti Khadijah Hubadillah ◽

Mohd Hafiz Dzarfan Othman ◽

A. F. Ismail ◽

Mukhlis A. Rahman ◽

Juhana Jaafar

Keyword(s):

Phase Inversion ◽

Low Cost ◽

Pure Water ◽

Porous Ceramic ◽

Water Flux ◽

Hollow Fibre ◽

Hollow Fibre Membrane ◽

Fibre Membrane ◽

Pure Water Flux ◽

And Performance

Ceramic hollow fibre membrane (CHFM) demonstrated superior characteristics and performance in any separation application. The only problem associated with this kind of technology is the high cost. In order to effectively fabricate and produce low cost porous CHFM, a series of CHFMs made of kaolin were fabricated via combined phase inversion and sintering technique. The CHFMs from kaolin named as kaolin hollow fibre membranes (KHFMs) were studied at different kaolin contents of 35 wt.%, 37.5 wt.% and 40 wt.% sintered at 1200ºC. The result indicated that by varying kaolin contents, different morphologies were obtained due to changes in the viscosity of ceramic suspension containing kaolin. The optimum kaolin content for KHFM was identified. It was found that KHFM prepared at 37.5 wt% has a mechanical strength and pure water flux of A and B respectively.

Download Full-text