Microfracture technique forfull-thickness chondral defects: Technique and clinical results

1997 ◽  
Vol 7 (4) ◽  
pp. 300-304 ◽  
Author(s):  
J. Richard Steadman ◽  
William G. Rodkey ◽  
Steven B. Singleton ◽  
Karen K. Briggs
Keyword(s):  
Clinical Results ◽  
Chondral Defects

scholarly journals Augmentation Strategies following the Microfracture Technique for Repair of Focal Chondral Defects

Cartilage ◽  
2010 ◽  
Vol 1 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Eric J. Strauss ◽  
Joseph U. Barker ◽  
James S. Kercher ◽  
Brian J. Cole ◽  
Kai Mithoefer
Keyword(s):  
Treatment Options ◽  
Operative Management ◽  
Biomechanical Properties ◽  
Clinical Results ◽  
Symptomatic Improvement ◽  
Comprehensive Overview ◽  
Chondral Lesions ◽  
Repair Tissue ◽  
Chondral Defects ◽  
Augmentation Techniques

The operative management of focal chondral lesions continues to be problematic for the treating orthopedic surgeon secondary to the limited regenerative capacity of articular cartilage. Although many treatment options are currently available, none fulfills the criteria for an ideal repair solution, including a hyaline repair tissue that completely fills the defect and integrates well with the surrounding normal cartilage. The microfracture technique is an often-utilized, first-line treatment modality for chondral lesions within the knee, resulting in the formation of a fibrocartilaginous repair tissue with inferior biochemical and biomechanical properties compared to normal hyaline cartilage. Although symptomatic improvement has been shown in the short term, concerns about the durability and longevity of the fibrocartilaginous repair have been raised. In response, a number of strategies and techniques for augmentation of the first-generation microfracture procedure have been introduced in an effort to improve repair tissue characteristics and reduce long-term deterioration. Recent experimental approaches utilize modern tissue-engineering technologies including local supplementation of chondrogenic growth factors, hyaluronic acid, or cytokine modulation. Other second-generation microfracture-based techniques use different types of scaffold-guided in situ chondroinduction. The current article presents a comprehensive overview of both the experimental and early clinical results of these developing microfracture augmentation techniques.

scholarly journals Clinical Results of A Novel Arthroscopic Microfracture Technique For Chondral Lesions of The Lunate

2020 ◽  
Author(s):  
Bulent Ozcelik ◽  
Tugrul Yildirim
Keyword(s):  
Clinical Results ◽  
Chondral Defect ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Chondral Lesions ◽  
Chondral Defects ◽  
Ulnar Impaction ◽  
Significant Difference ◽  
Drilling Technique ◽  
Ulnar Impaction Syndrome

Abstract PurposeChondral lesions of the lunate are one of the causes of ulnar-sided pain, but there has been little interest to date in treating them. In this paper, we describe a modification of the subchondral drilling technique in which an 18-gauge (G) needle was used as a sleeve to guide a K-wire to the lunate chondral defect.MethodsEleven patients (nine women, two men) who had undergone a simultaneous arthroscopic wafer procedure and lunate microfracture between 2014 and 2017 were retrospectively reviewed. After completion of the arthroscopic wafer procedure, an 18G needle was placed into the joint via the 6R portal and the needle tip was inserted into the subchondral bone. A 0.8-mm K-wire was then advanced through the needle and the lunate was drilled to a 2–3-mm depth. It is possible to safely drill remaining areas by only changing the direction of the needle. ResultsEight patients met inclusion criteria. There was no significant difference between the preoperative and postoperative wrist range of motion (p>0.05). Grip strength was significantly improved postoperatively (p<0.05). According to the Mayo wrist scoring system, six and one patients had excellent and good results, respectively.ConclusionArthroscopic lunate microfracture is an effective treatment for chondral defects of the lunate in the setting of ulnar impaction syndrome, and using a needle as a sleeve can ease manipulation and increase accuracy. Level of Evidence: IV

Good clinical results with autologous matrix-induced chondrogenesis (Amic) technique in large knee chondral defects

2017 ◽  
Author(s):  
Alfredo Schiavone Panni ◽  
Chiara Del Regno ◽  
Giuseppe Mazzitelli ◽  
Rocco D’Apolito ◽  
Katia Corona ◽  
...  
Keyword(s):  
Clinical Results ◽  
Chondral Defects ◽  
Knee Chondral Defects

Correlation of Insulin Test Studies and Clinical Results in a Series of Peptic Ulcer Cases Treated by Vagotomy

1950 ◽  
Vol 14 (2) ◽  
pp. 214-227 ◽  
Author(s):  
Vernon A. Weinstein ◽  
Franklin Hollander ◽  
Frances U. Lauber ◽  
Ralph Colp
Keyword(s):  
Peptic Ulcer ◽  
Clinical Results ◽  
Insulin Test

Klinische Langzeitergebnisse der perkutanen transluminalen Angioplastie bei Patienten mit peripherer arterieller Verschlusskrankheit

VASA ◽  
2002 ◽  
Vol 31 (1) ◽  
pp. 36-42 ◽  
Author(s):  
. Bucek ◽  
Hudak ◽  
Schnürer ◽  
Ahmadi ◽  
Wolfram ◽  
...  
Keyword(s):  
Success Rate ◽  
Clinical Stage ◽  
Ankle Brachial Index ◽  
Clinical Situation ◽  
Clinical Results ◽  
Transluminal Angioplasty ◽  
Term Outcome ◽  
Long Term Outcome

Background: We investigated the long-term clinical results of percutaneous transluminal angioplasty (PTA) in patients with peripheral arterial occlusive disease (PAOD) and the influence of different parameters on the primary success rate, the rate of complications and the long-term outcome. Patients and methods: We reviewed clinical and hemodynamic follow-up data of 166 consecutive patients treated with PTA in 1987 in our department. Results: PTA improved the clinical situation in 79.4% of patients with iliac lesions and in 88.3% of patients with femoro-popliteal lesions. The clinical stage and ankle brachial index (ABI) post-interventional could be improved significantly (each P < 0,001), the same results were observed at the end of follow-up (each P < 0,001). Major complications occurred in 11 patients (6.6%). The rate of primary clinical long-term success for suprainguinal lesions was 55% and 38% after 5 and 10 years (femoro-popliteal 44% and 33%), respectively, the corresponding data for secondary clinical long-term success were 63% and 56% (60% and 55%). Older age (P = 0,017) and lower ABI pre-interventional (P = 0,019) significantly deteriorated primary clinical long-term success for suprainguinal lesions, while no factor could be identified influencing the outcome of femoro-popliteal lesions significantly. Conclusion: Besides an acceptable success rate with a low rate of severe complications, our results demonstrate favourable long-term clinical results of PTA in patients with PAOD.

Management of thoracic aortic lesions - the future is endovascular

VASA ◽  
2012 ◽  
Vol 41 (3) ◽  
pp. 163-176 ◽  
Author(s):  
Weidenhagen ◽  
Bombien ◽  
Meimarakis ◽  
Geisler ◽  
A. Koeppel
Keyword(s):  
Thoracic Aorta ◽  
Clinical Decision Making ◽  
Treatment Options ◽  
Clinical Decision ◽  
Clinical Results ◽  
Treatment Modalities ◽  
Traumatic Rupture ◽  
Descending Thoracic Aorta ◽  
New Treatment ◽  
Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the “state-of-the-art” treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

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