Higher cortical function deficits among acute stroke patients: The stroke data bank experience

Aim. We aimed to assess the efficacy of MLC601 on functional recovery in patients given MLC601 after an ischemic stroke.Methods. This is a retrospective cohort study comparing poststroke patients given open-label MLC601 (; 9 female) for three months and matching patients who did not receive MLC601 from our Stroke Data Bank. Outcome assessed was modified Rankin Scale (mRS) at three months and analyzed according to: (1) achieving a score of 0-2, (2) achieving a score of 0-1, and (3) mean change in scores from baseline.Results. At three months, 21 patients on MLC601 became independent as compared to 17 patients not on MLC601 (OR 1.79; 95% CI 0.62–5.2; ). There were twice as many patients () on MLC601 who attained mRS scores similar to their prestroke state than in the non-MLC601 group () (OR 3.14; 95% CI 1.1–9.27; ). Mean improvement in mRS from baseline was better in the MLC601 group than in the non-MLC601 group (−1.7 versus −0.9; mean difference −0.73; 95% CI −1.09 to −0.38; ).Conclusion. MLC601 improves functional recovery at 3 months postischemic stroke. An ongoing large randomized control trial of MLC601 will help validate these results.

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Data bank project for acute stroke patients

Nosotchu ◽

10.3995/jstroke.24.255 ◽

2002 ◽

Vol 24 (2) ◽

pp. 255-259

Author(s):

Shotai Kobayashi

Keyword(s):

Acute Stroke ◽

Data Bank ◽

Stroke Patients

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Safety of Combination Aspirin and Anticoagulation in Acute Ischemic Stroke

Annals of Pharmacotherapy ◽

10.1177/106002809402800401 ◽

1994 ◽

Vol 28 (4) ◽

pp. 441-443 ◽

Cited By ~ 3

Author(s):

Susan C. Fagan ◽

Heather R. Kertland ◽

Gretchen E. Tietjen

Keyword(s):

Data Bank ◽

Bleeding Complications ◽

Inpatient Setting ◽

Stroke Patients ◽

Bleeding Rate ◽

Risk Of Bleeding ◽

Major Bleed ◽

Severe Epistaxis ◽

The Mean ◽

Stroke Data Bank

OBJECTIVE: To assess the risk of bleeding complications in patients treated with combination aspirin and heparin for cerebral ischemia. DESIGN: A retrospective, cohort study. SETTING: A large urban teaching hospital. PATIENTS: One hundred charts of stroke patients who had received anticoagulation with or without aspirin therapy were identified from the Stroke Data Bank. Bleeding rates were compared between the two groups. RESULTS: Forty-two patients who had received heparin and/or warfarin in combination with aspirin were compared with 33 patients who had received anticoagulation alone. The mean duration of anticoagulant therapy was 8.0 and 8.4 days, respectively. Bleeding rates were not different between the two groups: 23.8 percent (10/42) (p=0.78) and 24.2 percent (8/33), respectively. Although the bleeding rate was substantial, there was only one major bleed (severe epistaxis) occurring in a patient receiving anticoagulation only. No patient had an intracerebral hemorrhage. CONCLUSIONS: Our data suggest that combination antithrombotic therapy is safe in a controlled, inpatient setting.

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Silent cerebral infarction in stroke patients: Results from the klosterneuburg stroke data bank (Austria)

Journal of Stroke and Cerebrovascular Diseases ◽

10.1016/s1052-3057(10)80140-5 ◽

1994 ◽

Vol 4 (1) ◽

pp. 13-17 ◽

Cited By ~ 5

Author(s):

Michael Brainin ◽

Andreas Seiser ◽

Michaela Steiner ◽

Yasmin Dastmaltschi

Keyword(s):

Cerebral Infarction ◽

Data Bank ◽

Stroke Patients ◽

Silent Cerebral Infarction ◽

Stroke Data Bank

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Clinical discriminators between acute brain hemorrhage and infarction: a practical score for early patient identification

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2002000200001 ◽

2002 ◽

Vol 60 (2A) ◽

pp. 185-191 ◽

Cited By ~ 5

Author(s):

Ayrton R. Massaro ◽

Ralph L. Sacco ◽

Milberto Scaff ◽

J.P. Mohr

Keyword(s):

Acute Stroke ◽

External Validation ◽

Clinical Information ◽

Data Bank ◽

Brain Hemorrhage ◽

Patient Identification ◽

Treatment Delays ◽

Emergency Personnel ◽

New Treatments ◽

Stroke Data Bank

New treatments for acute stroke require a rapid triage system, which minimizes treatment delays and maximizes selection of eligible patients. Our aim was to create a score for assessing the probability of brain hemorrhage among patients with acute stroke based upon clinical information. Of 1805 patients in the Stroke Data Bank, 1273 had infarction (INF) and 237 had parenchymatous hemorrhage (HEM) verified by CT. INF and HEM discriminators were determined by logistic regression and used to create a score. ROC curve was used to choose the cut-point for predicting HEM (score <= 2), with sensitivity of 76% and specificity of 83%. External validation was done using the NOMASS cohort. Although the use of a practical score by emergency personnel cannot replace the gold-standard brain image differentiation of HEM from INF for thrombolytic therapy, this score can help to select patients for stroke trials and pre-hospital treatments, alert CT scan technicians, and warn stroke teams of incoming patients to reduce treatment delays.

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The role of nursing in the rehabilitation of acute stroke patients: Toward a unified theoretical perspective

Pflege ◽

10.1024/1012-5302.12.1.21 ◽

1999 ◽

Vol 12 (1) ◽

pp. 21-27

Author(s):

Marit Kirkevold

Keyword(s):

Acute Stroke ◽

Theoretical Perspective ◽

Stroke Patients ◽

Role Of Nursing ◽

Rolle Der Pflegenden

Eine Übersicht der bestehenden Literatur weist auf Unsicherheiten bezüglich der spezifischen Rolle der Pflegenden in der Rehabilitation von Hirnschlagpatientinnen und -patienten hin. Es existieren zwei unterschiedliche Begrifflichkeiten für die Rolle der Pflegenden, keine davon bezieht sich auf spezifische Rehabilitationsziele oder Patientenergebnisse. Ein anfänglicher theoretischer Beitrag der Rolle der Pflege in der Genesung vom Hirnschlag wird als Struktur unterbreitet, um die therapeutischen Aspekte der Pflege im Koordinieren, Erhalten und Üben zu vereinen. Bestehende Literatur untermauert diesen Beitrag. Weitere Forschung ist jedoch notwendig, um den spezifischen Inhalt und Fokus der Pflege in der Genesung bei Hirnschlag zu entwickeln.

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