scholarly journals CE1 COST-EFFECTIVENESS MODEL OF RECOMBINANT HUMAN CHORIONIC GONADOTROPIN (R-HCG) VERSUS URINARY HCG (U-HCG) FOR ASSISTED REPRODUCTIVE TECHNIQUES (ART) IN THE USA

2003 ◽  
Vol 6 (6) ◽  
pp. 624
Author(s):  
A Beresniak ◽  
S Daya ◽  
JP Auray ◽  
J Schertz ◽  
K Silverberg ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Assisted Reproductive Techniques ◽  
Effectiveness Model ◽  
The Usa ◽  
Reproductive Techniques

scholarly journals Effects of human chorionic gonadotropin intrauterine injection on oocyte retrieval day on assisted reproductive techniques outcomes: An RCT

2021 ◽  
pp. 773-780
Author(s):  
Robabe Hosseinisadat ◽  
Lida Saeed ◽  
Sareh Ashourzadeh ◽  
Sedigheh Safar Heidari ◽  
Victoria Habibzadeh
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Oocyte Retrieval ◽  
Pregnancy Rates ◽  
Clinical Pregnancy ◽  
Assisted Reproductive Techniques ◽  
Control Group ◽  
Case Group ◽  
Reproductive Techniques ◽  
Clinical Pregnancy Rates

Background: Several mediators play an important role in implantation. One of these mediators is human chorionic gonadotropin (HCG). Objective: To evaluate the effects of HCG intrauterine injection on the day of oocyte retrieval on the result of assisted reproductive techniques (ART). Materials and Methods: In this randomized clinical trial study, 126 women who were referred to Afzalipour Infertility Center between December 2018 to December 2019 undergoing in vitro fertilization/intracytoplasmic sperm injection cycles were enrolled and assigned to two groups of: a case (n = 62) and a control group (n = 64). The protocols for both groups were the same; except that the case group was injected with the protocols for both groups were the same, except that the case group was injected with 1000 IU of HCG into uterine cavity following the oocyte puncture, while no medication was administered to the control group. The implantation rate, chemical pregnancy, clinical pregnancy, and abortion rates were compared between the two groups. Results: Positive chemical pregnancy was seen in 15 (27.3%) cases of the case group and 14 (25.5%) of the control group. No significant difference was seen in the chemical and clinical pregnancy rates between the groups. The abortion rate was higher in the control group but that was not significant. Conclusion: A 1000 IU of HCG intrauterine injection after oocyte retrieval does not improve implantation, chemical or clinical pregnancy rates in ART cycles. Further studies are needed to clearly understand the role of HCG intrauterine injection in the day of oocyte retrieval in ART outcomes. Key words: Oocyte retrieval, Chorionic gonadotropin, Pregnancy, Assisted reproductive techniques.

scholarly journals Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques

2017 ◽  
Vol 15 (3) ◽  
pp. 273-277 ◽  
Author(s):  
Renato de Oliveira ◽  
Fernanda Godoy Cabral ◽  
Waldemar de Almeida Pereira Carvalho ◽  
Emerson Barchi Cordts ◽  
Bianca Bianco ◽  
...  
Keyword(s):  
Pregnancy Rate ◽  
Likelihood Ratio ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Positive Likelihood Ratio ◽  
Negative Likelihood Ratio ◽  
Assisted Reproductive Techniques ◽  
Progesterone Level ◽  
Predictive Capacity ◽  
Reproductive Techniques

ABSTRACT Objective To evaluate the predictive capacity for pregnancy of the progesterone level on the day of administering human chorionic gonadotropin, in women submitted to assisted reproductive techniques. Methods An observational study with 914 women submitted to assisted reproductive techniques from August 2014 to June 2016. Results Total pregnancy rate was 34.58%; in that, the pregnancy rate in women <35 years, between 35 and 38, and >38 years was, respectively, 42.3%, 38.7% and 16.1% (p<0.001). For embryo transfer in the same cycle, and progesterone of 1.3ng/dL, sensitivity was 4.78%, specificity, 84.18%, accuracy, 56.72%, positive likelihood ratio of 0.3019, and negative likelihood ratio of 1.1312, with receiver operating characteristic curve of 0.46 (95%CI: 0.42-0.49). Conclusion The progesterone level on the day of administering human chorionic gonadotropin of 1.3ng/dL differs from that empirically adopted at the study site (1.7ng/dL), and has a better predictive capacity for pregnancy in the patients studied. However, the low sensitivity of this examination raises questions about its real importance.

Normal Production of Human Chorionic Gonadotropin in Perimenopausal and Menopausal Women and After Oophorectomy

2009 ◽  
Vol 19 (9) ◽  
pp. 1556-1559 ◽  
Author(s):  
Laurence A. Cole ◽  
Sarah A. Khanlian ◽  
Carolyn Y. Muller
Keyword(s):  
New England ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Organ Transplant ◽  
Bilateral Oophorectomy ◽  
Cancer Treatments ◽  
Low Level ◽  
The Usa ◽  
Reference Service ◽  
Normal Production

Background:The normal pituitary production of human chorionic gonadotropin (hCG) alongside luteinizing hormone, and its presence in women after bilateral oophorectomy, during perimenopause and menopause, as measured in serum and urine, has been known for 30 years and is described in numerous publications. Last year our group discussed this finding in a correspondence to the editor in the March 15th issue of New England Journal of Medicine, yet the misinterpretation of low-level hCG in these women seems to have increased in magnitude.Methods:This is an outcomes study of 36 cases of menopausal hCG referred to the USA hCG Reference Service over a 1-year period, from March 2007 to March 2008.Results:Eight cases occurred in women after oophorectomy, 28 were women in menopause/perimenopause. Surgery was postponed in 5 (14%) of 36 cases, and in 3 cases (8%), chemotherapy was unnecessarily administered. In 2 cases, computed tomography scans were cancelled. The average hCG detected was 10 ± 7.2 IU/L in cases receiving an oophorectomy and 9.8 ± 6.7 in perimenopause and 11 ± 6.2 IU/L in menopause cases.Conclusions:Low-level hCG production in woman in physiologic perimenopause, in menopause, or in women with prior bilateral oophorectomy is a normal biologic and biochemical phenomenon. Management protocols in all fields need to be changed to accept pituitary hCG as normal and recognize the clinical maneuvers that will secure the diagnosis. Understanding this physiology will avoid needless delays in necessary therapies such as organ transplant procedures and will limit the misadventure of prescribing unnecessary cancer treatments.

The efficacy and cost effectiveness of embryo cryopreservation compared with other assisted reproductive techniques

1995 ◽  
Vol 64 (3) ◽  
pp. 647-650 ◽  
Author(s):  
Bradley J. Van Voorhis ◽  
Craig H. Syrop ◽  
Brian D. Allen ◽  
Amy E.T. Sparks ◽  
Dale W. Stovall
Keyword(s):  
Cost Effectiveness ◽  
Assisted Reproductive Techniques ◽  
Embryo Cryopreservation ◽  
Reproductive Techniques

Human Chorionic Gonadotropin and CA 15-3 Producing Adenocarcinoma

1998 ◽  
Vol 37 (08) ◽  
pp. 297-298 ◽  
Author(s):  
A. Özet ◽  
A. Arpaci ◽  
S. Kömiircü ◽  
G. Üçkaya
Keyword(s):  
Lung Adenocarcinoma ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Carbohydrate Antigen ◽  
Beta Subunit ◽  
Cancer Antigen ◽  
First Report ◽  
Primary Lung Adenocarcinoma ◽  
Adenocarcinoma Of Lung

Summary50 years old man suffering from primary lung adenocarcinoma presented with high levels of both beta subunit human chorionic gonadotropin (βHCG) and cancer antigen 15-3 (CA 15-3) in the absence of elevated carcinoembrionic antigen (CEA), alfa fetoprotein (AFP) and carbohydrate antigen 19-9 (CA 19-9). Although βHCG or CA 15-3 high levels were reported in adenocarcinoma of lung, this is the first report of a patient with high levels of both markers.

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