Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study

2005 ◽  
Vol 6 (8) ◽  
pp. 566-572 ◽  
Author(s):  
Stefan Krüger ◽  
Ann-Sophie Silber ◽  
Christoph Engel ◽  
Heike Görgens ◽  
Elisabeth Mangold ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Sequence Variation ◽  
Case Control Study ◽  
Age Of Onset ◽  
Cancer Susceptibility ◽  
Susceptibility Gene ◽  
Case Control ◽  
Prostate Cancer Susceptibility ◽  
Cancer Susceptibility Gene ◽  
Control Study

scholarly journals DPYD genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from Slovakia

2017 ◽  
Vol 36 (05) ◽  
pp. 557-563
Author(s):  
Tatiana Matáková ◽  
Erika Halašová ◽  
Henrieta Škovierová ◽  
Anton Dzian ◽  
Dušan Dobrota ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Haplotype Analysis ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Case Control ◽  
Control Study

scholarly journals XPG Gene Polymorphisms Contribute to Colorectal Cancer Susceptibility: A Two-Stage Case-Control Study

2016 ◽  
Vol 7 (12) ◽  
pp. 1731-1739 ◽  
Author(s):  
Rui-Xi Hua ◽  
Zhen-Jian Zhuo ◽  
Jinhong Zhu ◽  
Shao-Dan Zhang ◽  
Wen-Qiong Xue ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Gene Polymorphisms ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Case Control ◽  
Two Stage ◽  
Control Study

Positive correlation between interleukin-1 receptor antagonist gene 86bp VNTR polymorphism and colorectal cancer susceptibility: a case-control study

2018 ◽  
Vol 67 (1) ◽  
pp. 151-156 ◽  
Author(s):  
Mostafa Ibrahimi ◽  
Maryam Moossavi ◽  
Ehsan Nazemalhosseini Mojarad ◽  
Mahsa Musavi ◽  
Milad Mohammadoo-khorasani ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Receptor Antagonist ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Interleukin 1 ◽  
Case Control ◽  
Positive Correlation ◽  
Vntr Polymorphism ◽  
Interleukin 1 Receptor Antagonist ◽  
Control Study

scholarly journals Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk of Colorectal Cancer in the Macedonian Population

2008 ◽  
Vol 11 (2) ◽  
pp. 17-24 ◽  
Author(s):  
N Matevska ◽  
T Josifovski ◽  
A Kapedanovska ◽  
Z Sterjev ◽  
Z Serafimoska ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Methylenetetrahydrofolate Reductase ◽  
Case Control Study ◽  
Age Of Onset ◽  
Case Control ◽  
Mthfr Gene ◽  
Inverse Association ◽  
C677t Polymorphism ◽  
677T Allele ◽  
Control Study

Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk of Colorectal Cancer in the Macedonian PopulationMethylenetetrahydrofolate reductase (MTHFR) regulates the flow of folate groups between DNA synthesis and DNA methylation. A common C677T substitution (Ala222Val) in exon 4 of the MTHFR gene has been linked with the risk of colorectal cancer (CRC). To assess this risk in the Macedonian population, we conducted a case-control study of 413 randomly selected CRC patients and 185 controls without a clinical diagnosis of CRC. We found a statistically significant inverse association between the MTHFR T allele (35.35% for the patients and 41.35% for the controls) and the CRC risk [odds ratio (OR) 0.776; 95% confidence interval (95% CI) 0.603-0.997;p= 0.047). The prevalence of the MTHFR T allele is lower in patients with advanced CRC (Duke' s stage C and D) and with microsatellite instable tumors (MSI+), indicating the inverse association with the CRC aggressiveness and MSI status. This effect seems to be independent of gender, age of onset and localization. We concluded that the MTHFR 677T allele is more likely to have a protective effect on CRC development and progression in the Macedonian population.

Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibility: a case–control study

Tumor Biology ◽  
2014 ◽  
Vol 35 (12) ◽  
pp. 12059-12067 ◽  
Author(s):  
Suresh Govatati ◽  
Gopi Krishna Singamsetty ◽  
Nayudu Nallabelli ◽  
Sravanthi Malempati ◽  
Pasupuleti Sreenivasa Rao ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cyclin D1 ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Case Control ◽  
Control Study ◽  
E Cadherin
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