Atypical glandular cells and risk of cervical cancer

2016 ◽  
Vol 17 (3) ◽  
pp. e96 ◽  
Author(s):  
Talha Khan Burki
BMJ ◽  
2016 ◽  
pp. i276 ◽  
Author(s):  
Jiangrong Wang ◽  
Bengt Andrae ◽  
Karin Sundström ◽  
Peter Ström ◽  
Alexander Ploner ◽  
...  

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Fasogbon Samuel Ayobami

A cervical lesion is an area of abnormal tissue found on the cervix, which is the lower end of a woman’s uterus. The type of the lesion can be atypical squamous cells, squamous intraepithelianeoplasia, and atypical glandular cells. The early stages of cervical cancer may be asymptomatic. In advanced disease, there may be metastases to the abdomen, lungs or any other organ. Infection with some types of human papilloma virus (HPV) is the highest risk factor for cervical cancer which can be transmitted due to multiple sex partners, followed by smoking. Other risk factors include human immunodeficiency virus (HIV), early age at first sexual intercourse, early age at first pregnancy, tobacco use, exposure to passive smoke and other related factors. It is therefore recommended that all the risk factors should be avoided to reduce cervical cancer in the society and women should go for regular cervical screening as early detection can easily be treated.


2011 ◽  
Vol 57 (2) ◽  
pp. 229-233 ◽  
Author(s):  
Juliana Pedrosa de Holanda Marques ◽  
Lívia Bandeira Costa ◽  
Ana Paula de Souza e Pinto ◽  
Anacássia Fonseca de Lima ◽  
Maria Eugênia Leite Duarte ◽  
...  

2010 ◽  
Vol 37 (6) ◽  
pp. 496-500 ◽  
Author(s):  
Pitkanya Sawangsang ◽  
Charuwan Sae-Teng ◽  
Prapaporn Suprasert ◽  
Jatupol Srisomboon ◽  
Surapan Khunamornpong ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-17 ◽  
Author(s):  
Karem R. Domínguez Hernández ◽  
Alberto A. Aguilar Lasserre ◽  
Rubén Posada Gómez ◽  
José A. Palet Guzmán ◽  
Blanca E. González Sánchez

Cervical cancer is the second largest cause of death among women worldwide. Nowadays, this disease is preventable and curable at low cost and low risk when an accurate diagnosis is done in due time, since it is the neoplasm with the highest prevention potential. This work describes the development of an expert system able to provide a diagnosis to cervical neoplasia (CN) precursor injuries through the integration of fuzzy logics and image interpretation techniques. The key contribution of this research focuses on atypical cases, specifically on atypical glandular cells (AGC). The expert system consists of 3 phases: (1) risk diagnosis which consists of the interpretation of a patient’s clinical background and the risks for contracting CN according to specialists; (2) cytology images detection which consists of image interpretation (IM) and the Bethesda system for cytology interpretation, and (3) determination of cancer precursor injuries which consists of in retrieving the information from the prior phases and integrating the expert system by means of a fuzzy logics (FL) model. During the validation stage of the system, 21 already diagnosed cases were tested with a positive correlation in which 100% effectiveness was obtained. The main contribution of this work relies on the reduction of false positives and false negatives by providing a more accurate diagnosis for CN.


Author(s):  
Juliana Pedrosa de Holanda Marques ◽  
Lívia Bandeira Costa ◽  
Ana Paula de Souza e Pinto ◽  
Anacássia Fonseca de Lima ◽  
Maria Eugênia Leite Duarte ◽  
...  

2005 ◽  
Vol 15 (2) ◽  
pp. 366-371 ◽  
Author(s):  
D. E. Heron ◽  
A. Axtel ◽  
K. Gerszten ◽  
A. Amortegui ◽  
J. Kelley ◽  
...  

Cervical cancer during pregnancy is rare, occurring in approximately 3% of cervical cancer cases. Considerable controversy exists as to the long-term prognosis of patients diagnosed during pregnancy. A 32-year-old female presented with vaginal spotting in April 1998. A prenatal smear in December 1996 revealed atypical glandular cells of undetermined significance. A sterile speculum exam in April 1997 at 31-week gestational age revealed a polyp on the anterior lip of the cervix, pathology consistent with a well-differentiated villoglandular adenocarcinoma. In August 1997, the patient underwent a radical hysterectomy with pelvic/para-aortic lymphadenectomy. In April 2001, she represented with nodular perineal mass in the episiotomy incision. She received preoperative radiotherapy with a near-complete response and remained without disease for >10 months. It appears that a less radical procedure can offer significant therapeutic value. Preoperative radiotherapy proved effective at achieving a near-complete response. The patient underwent a wide local excision of the perineal area with resultant negative margins


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