Abstract #159 A Case of Sinonasal Mass Presenting as Tumor-Induced Osteomalacia

Background: Aim and objectives of the study were to analyze and study the diverse presentations of unilateral nasal mass and to identify the suggestive features of neoplastic pathology in adult’s population at a tertiary referral hospital.Methods: A retrospective analysis of 90 patients presented with unilateral sinonasal mass, reported to the Rhinology and Skull Base Clinic at the department of ENT in King Fahad Specialist Hospital, Dammam. The parameters include patient history, clinical assessments and histopathological examinations, which were supplemented with radiological investigations.In addition, demographic information and histopathological examinations for patients, who underwent surgical excision was analyzed for correlation with clinical diagnosis. Results: The reported cases are 55 males and 35 females with a median follow-up period of 12 months, ranging from 2-72 months. Nasal obstruction is the major symptom 34 (38%), 25 (27.8%) cases were reported with nasal mass and clinical diagnosis indicates 18 (20%) cases of malignancy. Type of disease and gender demonstrates low significance (p=0.023), whereas the diagnosis with age is highly significant (p=0.005).Conclusions: Carcinoma, inflammatory polyposis, inverted papilloma and allergic fungal sinusitis were the highest histological diagnosis. The clinical diagnosis and the suggestive features of radiological findings mostly resembled the histological findings. In contrary to the resemblance, the histological finding reveals the general diagnosis of nasal mass to the precise diagnosis, especially the fatal conditions like carcinoma. The high rate of malignancy and its suggestive radiological findings indicates that the specialists should consider the cases with caution to carryout histological analysis to rule out the probability of neoplasm.

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Diverse Diagnosis of a Single Sinonasal Mass and how was Mystery Solved

Journal of Tumor Research ◽

10.35248/2684-1258.15.1.102 ◽

2015 ◽

Vol 01 (01) ◽

Author(s):

Gayatri Gogoi ◽

Saikia P ◽

Borgohain M ◽

Utpal Dutta ◽

Daijy Kakoti

Keyword(s):

Sinonasal Mass

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SINONASAL MASS - A DIVERSE CLINICOPATHOLOGICAL ENTITY – AN EXPERIENCE IN A TERTIARY CARE CENTRE IN THE NORTH EASTERN INDIA

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2016/1504 ◽

2016 ◽

Vol 5 (89) ◽

pp. 6651-6656

Author(s):

Soumyajit Das ◽

Debajit Das

Keyword(s):

Tertiary Care ◽

Care Centre ◽

Eastern India ◽

Tertiary Care Centre ◽

The North ◽

Sinonasal Mass ◽

North Eastern ◽

North Eastern India

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Sinonasal Manifestation of Rosai-Dorfman Syndrome

Clinical Rhinology An International Journal ◽

10.5005/jp-journals-10013-1230 ◽

2015 ◽

Vol 8 (1) ◽

pp. 43-45

Author(s):

Kiran Mishra ◽

Lakshmi Vaid ◽

Vivek Gogia

Keyword(s):

Lymph Nodes ◽

Nasal Cavity ◽

Clinical Presentation ◽

Cervical Lymph Nodes ◽

Radiographic Findings ◽

Nasal Mass ◽

Massive Lymphadenopathy ◽

Sinonasal Mass ◽

Rosai Dorfman Disease ◽

Benign Course

ABSTRACT Sinus histiocytosis with massive lymphadenopathy (SHML) (also known as Rosai-Dorfman syndrome) is a rare, idiopathic, benign and self-limiting histiocytic proliferative disorder. It most commonly involves the cervical lymph nodes. The disease has a benign course and involvement of the nasal cavity as an extranodal site is exceptional. Here, we report a case of bilateral sinonasal mass with subsequent involvement of cervical lymph nodes in 22-year-old lady. Histological examination of the cervical lymph nodes and nasal mass biopsy demonstrated evidences of Rosai-Dorfman disease (RDD). The clinical presentation, histologic characteristics, radiographic findings and treatment of the disease are discussed. How to cite this article Vaid L, Jain N, Gogia V, Mishra K. Sinonasal Manifestation of Rosai-Dorfman Syndrome. Clin Rhinol An Int J 2015;8(1):43-45.

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Different Faces of Sinonasal Mass Lesions

Bengal Journal of Otolaryngology and Head Neck Surgery ◽

10.47210/bjohns.2020.v28i3.288 ◽

2021 ◽

Vol 28 (3) ◽

pp. 193-197

Author(s):

Devika T ◽

Shubha P Bhat ◽

Vadisha Srinivas Bhat ◽

Rajeshwary Aroor ◽

Satheesh Kumar Bhandary B ◽

...

Keyword(s):

Nasal Cavity ◽

Clinical Diagnosis ◽

Clinical Features ◽

Histopathological Examination ◽

Nasal Discharge ◽

Histopathological Diagnosis ◽

Appropriate Treatment ◽

Sinonasal Mass ◽

Wide Range ◽

Neoplastic Lesions

Introduction Mass in the nasal cavity presents with a wide range of symptoms, when a presumptive diagnosis is often made with the help of imaging and endoscopy. This study focussed on correlating clinical diagnosis with the histopathological diagnosis so that appropriate treatment can be offered to improve the quality of life of the patient. Materials and Methods The study included 120 cases who presented with symptoms and signs of mass in the nasal cavity, undergoing surgery or diagnostic biopsy. They were evaluated with a detailed history and clinical examination, diagnostic nasal endoscopy, and relevant radiological investigations. Histopathological examination of the biopsy of the excised specimen was performed by Haematoxylin and Eosin stain. Special stains and Immunohistochemistry (IHC) were performed whenever indicated. The clinical diagnosis was correlated with histopathological diagnosis. Results Nasal obstruction was the most frequent symptom followed by nasal discharge. Non-neoplastic lesions made up 85% of cases, while16% of cases were proved as neoplastic lesions. Among neoplastic lesions, 7% were benign, and 9% were malignant. The inflammatory polyp was the most common non-neoplastic lesion. Fischer's exact test showed a correlation between clinical diagnosis and histopathological diagnosis. Non-neoplastic lesions were common in the 4th decade of life; benign lesions were common in the 3rd decade of life, while malignant lesions were common in the 5th decade of life. Conclusion Sinonasal masses present with overlapping clinical features, and sometimes the definite diagnosis is possible only by histopathological examination of the specimen. However, in the presence of characteristic clinical features, accurate clinical diagnosis is possible in most cases, and appropriate treatment can be performed without delay, pending histopathological examination.

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