A 006 Elevation in Systolic Blood Pressure and Fasting Blood Glucose Impairs the Improvement of Endothelial Function Induced by Short-term Red Wine Consumption

2009 ◽  
Vol 10 (3) ◽  
pp. 6
Author(s):  
FHY Cesena ◽  
SR Coimbra ◽  
ACM Andrade ◽  
AM Benjo ◽  
PL Luz
Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1982
Author(s):  
In Young Cho ◽  
Kyungdo Han ◽  
Dong Wook Shin ◽  
Mi Hee Cho ◽  
Jung Eun Yoo ◽  
...  

We investigated whether visit-to-visit variability in metabolic parameters is associated with lung cancer risk. We used nationally representative data from the Korean National Health Insurance System, and 8,011,209 lung-cancer-free subjects who underwent over three health examinations from 2005 to 2010 were followed until 2017. Variability of fasting blood glucose, total cholesterol, systolic blood pressure, and body weight were measured by the variability independent of the mean, assessed by quartiles. There were 44,982 lung cancer events. The hazard ratio (HR) and 95% confidence interval (CI) for lung cancer risk was 1.07 (1.04, 1.10) for fasting blood glucose in the highest quartile, 1.08 (1.05, 1.10) for systolic blood pressure, 1.04 (1.01, 1.07) for weight, and 1.11 (1.08, 1.14) for total cholesterol. When comparing ≥3 vs. 0 high-variability metabolic parameters, the HR for lung cancer was 1.18 (95% CI, 1.14, 1.22). However, while ≥3 high-variability parameters showed an increased lung cancer risk in men (HR 1.26, 95% CI 1.21, 1.31), women did not show increased risk (HR 0.99, 95% CI 0.92, 1.06). High variability in each metabolic parameter, and a higher number of high-variability parameters, were associated with increased lung cancer risk.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 467
Author(s):  
Mohammad Saifur Rohman ◽  
Mifetika Lukitasari ◽  
Dwi Adi Nugroho ◽  
Risa Ramadhiani ◽  
Nashi Widodo ◽  
...  

Background: Individually, green tea and green coffee have been extensively studied for mitigation of metabolic syndrome (MS) in both rats and humans; however, their combined effect requires further investigation. Thus, we compared the metabolic effect of combining green tea and decaffeinated light roasted green coffee on MS in rats. Methods: An MS animal model was constructed by feeding Sprague-Dawley rats with a high-fat-high-sucrose (HFHS) diet for eight weeks and a low dose of streptozotocin (STZ) injection at week 2. Rats fed with HFHS diets and injected with STZ successfully developed MS phenotypes, indicated by higher body weight, systolic blood pressure, plasma triglyceride level, plasma fasting blood glucose level, and lower plasma HDL-C level, compared to those fed with a normal chow diet. Subsequently, MS rats were continuously fed with HFHS and divided into four groups: MS rats, MS with 300 mg/bw.t green tea extract (GT), MS with 200 mg/bw.t green coffee extract (GC), and MS with combined green tea and green coffee extract (CM) for nine weeks. Results: Combining green tea and green coffee have synergistic effects on reducing plasma fasting blood glucose and triglyceride level. Inflammatory markers both in plasma and liver tissue robustly decreased in CM group rats. However, the reduction of systolic blood pressure was observed only in GT and CM groups. Moreover, all treatment resulted in an increase in plasma HDL-C level in MS rats. Conclusions: Our data highlighted that, in MS animal models, combined green tea and decaffeinated light roasted green coffee augment their several individual beneficial effects of improved metabolic parameters and modulated inflammatory genes.


2021 ◽  
Vol 28 (1) ◽  
pp. 1-10
Author(s):  
Tinu Sharma ◽  
Kanthanathan Subbiah ◽  
P Antony Leo Aseer

Background/Aims The causes of cervicobrachial pain are highly variable and it is often difficult to predict patient response to multimodal treatments, such as neural mobilisation. Little research has focused on identifying subgroups of patients who may show improvement following neural mobilisation. This study aimed to identify the variables that may influence response to nerve mobilisation in individuals with cervicobrachial pain. Methods A quasi-experimental prospective single-arm study was conducted with 50 participants. Data were collected on various potentially prognostic variables from baseline questionnaires, medical history and physical examination. Participants received 10 days of pain modulation treatment and nerve mobilisation exercises. The Neck Disability Index, Numeric Pain Rating Scale and Upper Limb Tension Test were performed before and after treatment to determine the effect of nerve mobilisation. Data were analysed using descriptive statistics, univariate correlation, multivariate stepwise logistic regression and non-parametric testing at α≤0.05. Results Four variables had a positive influence on treatment outcome: age <41 years, duration of symptoms ≤1 year, fasting blood glucose level ≤5.6 mmol/L (≤100 mg/dL) and systolic blood pressure ≤140 mmHg. On multiple linear regression, the presence of hypertension and diabetes were strongly associated with poor outcomes following nerve mobilisation. Conclusions Younger individuals with normal fasting blood glucose and systolic blood pressure who have had cervicobrachial pain for less than a year are more likely to benefit from pain modulation and neural mobilisation.


2019 ◽  
Vol 7 (2) ◽  
pp. 107-114
Author(s):  
Shafira Tri Handayani ◽  
Yuwono Setiadi ◽  
Yuniarti Yuniarti

Background : Obesity in adolescence associated with the incidence of metabolic syndrome. The metabolic syndrome is a group of metabolic disorders characterized by high blood pressure, high fasting blood glucose, high triglycerides, low HDL and central obesity. An increasing number of metabolic syndrome in line with the increase in the number of obesity. Based on RISKESDAS 2013 increased the proportion of central obesity from 2007 to 2013 by 18.8% to 26.6%. The prevalence of central obesity in Semarang 21.5%.Aim : Knowing the relationship among intake with waist circumference, fasting blood glucose level and blood pressure in obese adolescents in SMAN 9 Semarang.Method : This study was an observational study with cross-sectional design. Sampling was conducted randomized to receive 47 samples. The data collected is macro nutrients intake factors with 24 hours recall method, weight, height, waist circumference, fasting blood glucose level and blood pressure. Data was collected by the method of anthropometry; interviews, blood pressure measurement and fasting blood glucose level measurement. The correlations test using linear regression.Results: There is a correlation between intake with waist circumference (p 0.046 0.05) with a moderate relationship (R = 0.454) and contributed 20.6%, there is a correlation between intake with fasting blood glucose level (0.039 p 0.05) with the level of relationship is (R = 0.448) and contributed 20.1%, there is a correlation between intake with systolic blood pressure (p 0.004 0.05) with a strong correlation (R = 0.556) and contributed 30.6%, and there is no correlation between intake factor with diastolic blood pressure (p 0.113 0.05) and contributed 16.3%.Conclusion: There is a correlation among intake with waist circumference, fasting blood glucose level and systolic blood pressure. There is no correlation between intake with diastolic blood pressure.


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242150
Author(s):  
Deviana A. S. Siregar ◽  
Davrina Rianda ◽  
Rima Irwinda ◽  
Annisa Dwi Utami ◽  
Hanifa Hanifa ◽  
...  

Background The prevalence of gestational hypertension and diabetes in pregnancy is increasing worldwide. Diet is a modifiable factor that may influence these conditions, but few studies have examined the association between diet quality and blood pressure and glucose profiles among pregnant women. Data are especially scarce for women in low- and middle-income countries (LMICs), where 90% of global pregnancies occur, and in urban settings. We, therefore, assessed these associations among 174 pregnant women in the Asian megacity of Jakarta in a cross-sectional study of the Brain Probiotic and LC-PUFA Intervention for Optimum Early Life (BRAVE) project. Methods Trained field-enumerators collected socio-demographic characteristics, measured Mid-Upper Arm Circumference (MUAC), and assessed diet by two 24-hour recalls, which were used to calculate the Alternate Healthy Eating Index for Pregnancy (AHEI-P). Blood pressure was measured by automated sphygmomanometer, and fasting blood glucose by capillary glucometer. General linear models were used to identify associations. Results The median AHEI-P score was 47.4 (IQR 19.1–76.6). The middle tertile of the AHEI-P score (39.59–56.58) was associated with a 0.4 SD (standardized effect size, 95% CI -0.7 to -0.06; p = 0.02) lower diastolic blood pressure compared with the lowest tertile (<39.59), after adjustment for level of education, smoking status, MUAC, gestational age, history of hypertension, and family history of hypertension. However, no associations were found between the AHEI-P score and systolic blood pressure and blood glucose. Conclusion Higher diet quality was associated with lower diastolic blood pressure among pregnant women in an urban LMIC community, but not with systolic blood pressure and blood glucose. A behavioral change intervention trial would be warranted to confirm the influence of diet quality on blood pressure and glucose levels and among pregnant women, and even before pregnancy.


2021 ◽  
Author(s):  
Moloko Matshipi ◽  
Hlengani James Siweya ◽  
Phuti Joanna Makgae

Obesity as directly measured by anthropometric parameters has been demonstrated to be associated with hypertension and type 2 diabetes mellitus, which are common risk factors for CVD. The study aimed at assessing the relationship between blood pressure, blood glucose and anthropometric parameters in Ellisras children. A total of 492 children aged 6 to 11 years, participated in the study. Neck circumference, waist circumference, body mass index, waist-to-height ratio, fasting blood glucose, systolic and diastolic blood pressure were measured using standard procedures. Linear regression showed significant association (P < 0.05) of anthropometric parameters (except waist-to-height ratio) with blood pressure. Fasting blood glucose was significantly associated with neck circumference when adjusted for age and gender. Positive correlation was found for systolic blood pressure with neck and waist circumference and body mass index in both genders and for diastolic blood pressure, the correlation was only found in boys. Fasting blood glucose was negatively correlated with neck circumference. Waist circumference (P = 0.025, β = 1.208, 95% CI = 1.017–1.285) was better than BMI (P = 0.046, β = 1.340, 95% CI = 1.005–1.788) in predicting elevated systolic blood pressure. These findings suggest that it is crucial to manage anthropometric parameters in the Ellisras community in order to decelerate the increase of hypertension and diabetes mellitus.


2020 ◽  
pp. 24-26
Author(s):  
Divya Sinha ◽  
S. R. Padmeodev ◽  
Debarshi Jana

An attempt was made to study the role of lipid profile serum Mg+2, and blood glucose in hypertension individuals. Moreover, all the parameters are analyzed biochemically. In about 80 samples (50cases and 30 controls) and it is observed that dyslipidemia is seen in Hypertensive individuals with no change in HDL concentration. There is no correlation of serum magnesium in hypertensive cases with controls. It has been observed that serum magnesium of hypertensive cases is slightly higher than that of normal individuals. Fasting blood glucose of hypertensive cases (101.62mg/dl ±33.78) is higher than that of Controls (82.46 mg/dl±10.8). This increase is statistically significant (p<0.001). But this increase may be due to the presence 12% diabetic cases present in the cases. Even then, there is a tendency of developing impaired glucose tolerance in hypertensive subjects. The blood pressure is noted separately as systolic blood pressure and diastolic blood pressures. The systolic blood pressure was more significant than the diastolic blood pressure with increasing age groups.


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